All Episodes

PubReading [244] - The long and short of it - L. Passmore & T. Tang

PubReading [243] - Liquid biopsies for residual disease and recurrence - J. Chee Ming Wan, N. Rosenfeld et al.

PubReading [242] - Single-particle cryo-EM at atomic resolution - T. Nakane, S. Scheres et al.

PubReading [241] - The neurons that restore walking after paralysis - C. Kathe, G. Courtine et al

PubReading [240] - Is my paper relevant for an international audience? - F. Fernandez-llimos

PubReading [239] - Triplex-forming properties and enzymatic incorporation of a base-modified nucleotide capable of duplex DNA recognition at neutral pH - D. Rusling

PubReading [238] - Heart regeneration using pluripotent stem cells - S. Kadota, Y. Tanaka, Y. Shiba

PubReading [237] - Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer - J. Niño, S. Bullman et al.

PubReading [236] - BioSimulators- a central registry of simulation engines and services for recommending specific tools - B. Shaikh, J. Karr et al.

PubReading [235] - How to...write a good research question - K. Mattick, J. Johnston and A. de la Croix

PubReading [234] - The importance of synthetic chemistry in the pharmaceutical industry - K. Campos, E. Parmee et al.

PubReading [233] - The importance of synthetic chemistry in the pharmaceutical industry - K. Campos, E. Parmee et al.

PubReading [232] - The multiple flavors of GoU pairs in RNA - E. Westhof, M. Yusupov, G. Yusupova

PubReading [231] - Light-activated communication in synthetic tissues - M. Booth, H. Bayley et al.

PubReading [230] - Does a Graphical Abstract Bring More Visibility to Your Paper? - E. Pferschy-Wenzig, A. Atanasov et al.

PubReading [229] - RNA-Puzzles toolkit- a computational resource of RNA 3D structure benchmark datasets, structure manipulation, and evaluation tools - M. Magnus, Z. Miao et al.

PubReading [228] - Data, data, burning deep, in the forests of the net - E. Westhof

PubReading [227] - Artificial intelligence in chemistry and drug design - N. Brown, N. Schneider et al

PubReading [226] - The threat of programmed DNA damage to neuronal genome integrity and plasticity - K. Caldecott, M. Ward and A. Nussenzweig

PubReading [225] - A brief guide to the science and art of writing manuscripts in biomedicine - Di. Forero, S. Lopez-Leon, G. Perry

PubReading [224] - Drug Design- Where We Are and Future Prospects - G. Zagotto and M. Bortoli

PubReading [223] - The Discovery of the DNA Double Helix - A. Klung

PubReading [222] - Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing - E. Schönegger, T. Frischmuth

PubReading [221] - Hairpin-like siRNA-Based Spherical Nucleic Acids - M. Vasher, G. Yamankurt, C. Mirkin

PubReading [220] - Interbase FRET in RNA: from A to Z - A. Fuechtbauer, M. Wilhelmsson et al.

PubReading [219] - An integrated workflow for crosslinking mass spectrometry - M. Mendes, J. Rappsilber et al

PubReading [218] - Covalent labeling of immune cells - L. Rösner, C. Konken, D. Depke, A. Rentmeister, M. Schäfers

PubReading [217] - Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies - C. Bettegowda, L. Diaz Jr et al

PubReading [216] - Bottom-Up Assembly of Synthetic Cells with a DNA Cytoskeleton - K. Jahnke, K. Göpfrich et al

PubReading [115] - Therapeutic application of sequence-specific binding molecules for novel genome editing tools - J. Nakao, T. Yamamoto and A. Yamayoshi

PubReading [214] - Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance - A. Bowden, S. Jackson et al.

PubReading [213] - Stabilisation of self-assembled DNA crystals by triplex-directed photo-cross-linking - H. Abdallah, N. Seeman et al.

PubReading [212] - Glyoxal oxidases: their nature and properties - M. Daou and C.Faulds

PubReading [211] - 3D DNA Crystals and Nanotechnology - P. Paukstelis and N. Seeman

PubReading [210] - Interbase‐FRET binding assay for pre‐microRNAs - M. Bood, M. Wilhelmsson, M. Grøtli et al.

PubReading [209] - Flipping the Switch: Innovations in Inducible Probes for Protein Profiling - S. McKenna, E. Fay and J. McGouran

PubReading [208] - Cystatin C as a biomarker of chronic kidney disease: latest developments - S. Benoit, E. Ciccia, P. Devarajan

PubReading [207] - Holliday junction-resolving enzymes—structures and mechanisms - David Lilley

PubReading [206] - The path for metal complexes to a DNA target - A. Komora and J. Barton

PubReading [205] - Targeting tumor cell senescence and polyploidy as potential therapeutic strategies - T. Saleh, D. Gewirtz et al.

PubReading [204] - Antibody targeting of E3 ubiquitin ligases for receptor degradation - H. Marei, F. de Sousa e Melo et al.

PubReading [203] - The mechanism of replication stalling and recovery within repetitive DNA - C. Cases-Delucchi, M. Daza-Martin, S. Williams & G. Coster

PubReading [202] - Potentialities of Gene Therapy in Pediatric Endocrinology - G. Frontino. M. Stancampiano, A. Aiuti

PubReading [201] - The cryo-EM method microcrystal electron diffraction (MicroED) - B. Nannenga and T. Gone

PubReading [200] - Stealth Fluorescence Labeling for Live Microscopy Imaging of mRNA Delivery - T. Baladi, M. Wilhelmsson et al

PubReading [199] - Live-seq enables temporal transcriptomic recording of single cells - W. Chen, B. Deplanke et al

PubReading [198] - Neutron crystallography: opportunities, challenges, and limitations - M. Blakeley, A. Podjarny et al

PubReading [197] - Nanopore microscope identifies RNA isoforms with structural colours - F. Bošković and U. Keyser

PubReading [196] - Radiation damage to biological samples: still a pertinent issue - E. Garman and M. Weik

PubReading [195] - Inflammatory and immune effects on tumor progression - K. Mehla and M. Hollingsworth

PubReading [194] - Biological functions of therapy-induced senescence in cancer - E. Fitsiou, A. Soto-Gamez and M. Demaria

PubReading [193] - A crystallization apparatus for temperature-controlled flow-cell dialysis with real-time visualization - N. Junius, M. Budayova-Spano et al.

PubReading [192] - Optimizing data collection for structure determination - A. GonzaÂlez

PubReading [191] - Review on mechanistic strategy of gene therapy in the treatment of disease - S. Alnasser

PubReading [190] - Contextualizing the Impostor “Syndrome” - S. Feenstra, J. Jordan et al.

PubReading [189] - Clinical Experience With Gene Therapy in Older Patients With Spinal Muscular Atrophy - S. Metesanz, E. Kichula et al.

PubReading [188] - m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation - S. Ho Boo, H. Ha, Y. Ki Kim

PubReading [188] - m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation - S. Ho Boo, H. Ha, Y. Kim

PubReading [187] - T-cell invigoration to tumour burden ratio associated with anti-PD-1 response - A. Huang, J. Wherry et al

PubReading [186] - Copper(II) and silver(I)‐1,10‐phenanthroline‐5,6‐dione complexes interact with double‐stranded DNA: further evidence of their apparent multi‐modal activity towards Pseudomonas aeruginosa - A. Galdino, A. los Santos et al.

PubReading [185] - A methodology and an instrument for the temperature-controlled optimization of crystal growth - M. Budayova-Spano, S. Cusak et al

PubReading [184] - Biophysical Techniques in Structural Biology - C. Dobson

PubReading [183] - From structure to function: Route to understanding lncRNA mechanism - J. Graf and M. Kretz

PubReading [182] - Three's a crowd – stabilisation, structure, and applications of DNA triplexes - M. Dalla Pozza, A. Abdullrahman, C. Cardin, G. Gasser and J. Hall

PubReading [181] - Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer - P. Torres-Ayuso and J. Brognard

PubReading [180] - Glioblastoma hijacks neuronal mechanisms for brain invasion - V. Venkataramani, F. Winkler et al.

PubReading [179] - Metallodrugs: Mechanisms of Action, Molecular Targets and Biological Activity - G. Ferrano and A. Merlino

PubReading [178] - Mass spectrometry techniques for imaging and detection of metallodrugs - S. Theiner, G. Koellensperger et al.

PubReading [177] - Systematic Review of miRNA as Biomarkers in Alzheimer’s Disease - S. Swarbrick, N. Wragg, S. Ghosh and A. Stolzing

PubReading [176] - miRNA Targeting: Growing beyond the Seed - L. Chipman and A. Pasquinelli

PubReading [175] - Solution Oligonucleotide APIs: Regulatory Considerations - C. Wetter. J. Tom et al.

PubReading [174] - All-atom simulations to studying metallodrugs/target interactions - P. Janos, A. Spinello and A. Magistrato

PubReading [173] - CAR T cell immunotherapy for human cancer - C. June, M. Milone et al.

PubReading [172] - Delivery of oligonucleotide-based therapeutics: challenges and opportunities - S. Hammond, V. Arechavala-Gomeza et.

PubReading [171] - Dual action of ketamine confines addiction liability - L. Simmler, C. Lüscher et al.

PubReading [170] - Accelerating reaction generality and mechanistic insight through additive mapping - C. Kullmer, D. MacMillan et al

PubReading [169] - The Epigenetic Basis of Hematopoietic Stem Cell Aging - A. Kramer and G. Challen

PubReading [168] - Advances of epigenetic editing - R. Gjaltema and M. Rots

PubReading [167] - Molecular Biology and Evolution of Cancer: From Discovery to Action - J. Somarelli, J. Townsend et al

PubReading [166] - Understanding the fate of DNA nanostructures inside the cell - C. Green, D. Mathur and I. Medinitz

PubReading [165] - Macrocyclic Metal Complex−DNA Conjugates for Electrochemical Sensing of Single Nucleobase Changes in DNA - J. Duprey, J. Tucker et al

PubReading [164] - DNA Nanostructures for Targeted Antimicrobial Delivery - I. Mela, C. Kaminiski et al

PubReading [163] - Synthetic protein-conductive membrane nanopores built with DNA - T. Diederichs, R. Tampé, S. Howorka et al.

PubReading [162] - The second decade of synthetic biology: 2010–2020 - F. Meng and T. Ellis

PubReading [161] - Even Cancer Cells Watch Their Cholesterol! - R. Riscal, N. Skuli and C. Simon

PubReading [160] - Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components - G. Padroni, G. Burley et al.

PubReading [159] - Designing Hydrogels for On-Demand Therapy - N. Oliva, N. Artzi et al.

PubReading [158] - Junctions in DNA: underexplored targets for therapeutic intervention - E. Ivens, M. Cominetti and M. Searcey

PubReading [157] - Cell-SELEX Technology - S. Ohuchi

PubReading [156] - Direct Nanopore Sequencing of Individual Full Length tRNA Strands - N. Thomas, R. Abu-Shumays et al

PubReading [155] - The central role of DNA damage in the ageing process - B. Schumacher, J. Pothof, Vijg and Hoeijmakers

PubReading [154] - Mitochondria‐ER Tethering in Neurodegenerative Diseases - R. Raeisossadati, M. Ferrari

PubReading [153] - The DNA methyltransferase family: a versatile toolkit for epigenetic regulation - Frank Lyko

PubReading [152] - Teaching photosensitizers a new trick: red light-triggered G-quadruplex alkylation by ligand co-localization - E. Cadoni, A. Madder et al

PubReading [151] - Chirality transmission in macromolecular domains - S. Pandey, C. Lou, H.Mao et al

PubReading [150] - 1‐Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis - R. Bereiter, R. Micura et al

PubReading [149] - Therapeutic design of peptide modulators of protein-protein interactions in membranes - T. Stone and C. Deber

PubReading [148] - The current landscape of nucleic acid therapeutics - J. Kulkarni, R. van der Meel et al.

PubReading [147] - Furan-containing polymeric Materials: Harnessing the Diels-Alder chemistry for biomedical applications - T. Gevrek and A. Sanyal

PubReading [146] - Pyrene-modified PNAs: Stacking interactions and selective excimer emission in PNA2DNA triplexes - A. Manicardi, L. Guidi, A. Ghidini and R. Corradini