All Episodes

PubReading [145] - CAR T cell therapy and the tumor microenvironment: Current challenges and opportunities - L. Fonkoua, S. Kenderian et al

PubReading [144] - What machine learning can do for developmental biology - P. Villoutreix

PubReading [143] - Homology directed correction, a new pathway model for point mutation repair catalyzed by CRISPR‐Cas - B. Sansbury, E. Kmiec et al

PubReading [142] - Artificial nucleic acid backbones and their applications in therapeutics, synthetic biology and biotechnology - S. Epple, A. El-Sagheer and T. Brown

PubReading [141] - Single-molecule fluorescence detection of a tricyclic nucleoside analogue - G. Samaan, B. Purse et al

PubReading [140] - Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis - R. D’Agata, M. Giuffrida and G. Spoto

PubReading [139] - Harnessing DNA as a Designable Scaffold for Asymmetric Catalysis: Recent Advances and Future Perspectives - JJ. Yum, H. Sugiyama and S. Park

PubReading [138] - Improving CRISPR–Cas specificity with chemical modifications in single-guide RNAs - D. Ryan, D. Dellinger et al

PubReading [137] - Double-headed nucleic acids condense the molecular information of DNA to half the number of nucleotides -K. Beck, P. Nielsen et al

PubReading [136] - A prebiotically plausible scenario of an RNA–peptide world - F. Müller, C. Chan, T. Carell

PubReading [135] - Structural basis for broad anti-phage immunity by DISARM - J. Bravo, D. Taylor et al

PubReading [134] - Tethering Carbohydrates to the Vinyliminium Ligand of Antiproliferative Organometallic Diiron Complexes - S. Schoch, M. Dalla Pozza, G. Gasser, F. Marchetti et al

PubReading [133] - Life in the light: nucleic acid photoproperties as a legacy of chemical evolution - A. Beckstead, B. Kohler

PubReading [132] - Unnatural bases for recognition of noncoding nucleic acid interfaces - S. Miao, D. Bong et al

PubReading [131] - Microneedling for Hair Loss - A. Gupta, M. Bamimore et al.

PubReading [130] - Computational analysis of next generation sequencing data and its applications in clinical oncology - R. Wadapurkar and Renu Vyas

PubReading [129] - Beginner’s guide to mass spectrometry–based proteomics - A. Sinha and M. Mann

PubReading [128] - Best practices for variant calling in clinical sequencing - D. Koboldt

PubReading [127] - Insufficient Evidence for ‘‘Autism-Specific’’ Genes - S. Myers, D. Ledbetter

PubReading [126] - Split light up aptamers as a probing tool for nucleic acids - Y. Gerasimovaa, D Nedorezovab and D. Kolpashchikov

PubReading [125] - How cryo-electron microscopy and X-ray crystallography complement each other - H. Wang, and J. Wang

PubReading [124] - A biomedical open knowledge network harnesses the power of AI to understand deep human biology - S. Baranzini, S. Huang et al

PubReading [123] - Next-Generation Sequencing Technologies - R. McCombie, J. McPherson, and E. Mardis

PubReading [122] - Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing - Z. Yuen, E. Eyras et al

PubReading [121] - Cone-shaped HIV-1 capsids are transported through intact nuclear pores - V. Zila, M. Beck et al

PubReading [120] - Modern epigenetics methods in biological research - Yuanyuan Li

PubReading [119] - CAR T‐cell therapy: Full speed ahead - D. Sermer and R. Brentjens

PubReading [118] - Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP) - E. Van Nostrand, G. Yeo et al

PubReading [117] - Real-time Voltammetric Anion Sensing Under Flow - S. Patrick, J. Davis

PubReading [116] - Improved protein structure prediction using potentials from deep learning - A. Senior, D. Hassabis et al.

PubReading [115] - The Current Revolution in Cryo-EM - E. Egelman

PubReading [114] - Oncogene-induced DNA damage: cyclic AMP steps into the ring - J. Fagin and J. Petrini

PubReading [113] - Highly accurate protein structure prediction with AlphaFold - J. Jumper, P. Kohli, D. Hassabis et al

PubReading [112] - Automated Tools to Advance High-Resolution Imaging in Liquid - G. Jonaid, D. Kelly

PubReading [111] - Chemical reprogramming of human somatic cells to pluripotent stem cells - J. Guang, H. Dang et al

PubReading [110] - Hallmarks of Cancer: New Dimensions - Douglas Hanahan

PubReading [109] - Novel therapeutic targets for cancer metastasis - K. Stoletov, P. Beatty and J. Lewis

PubReading [108] - Untapped Neuroimaging Tools for Neuro-Oncology: Connectomics and Spatial Transcriptomics - J. Germann, A. Boutet et al

PubReading [107] - Genome editing for Duchenne muscular dystrophy: a glimpse of the future? - C. Kupatt, M. Walter et al

PubReading [106] - The Ultimate (Mis)match: When DNA Meets RNA - B. Palancade and R. Rothstein

PubReading [104] - Structural principles of CRISPR-Cas enzymes used in nucleic acid detection - A. Dasa, H. Li et al

PubReading [103] - IceBreaker: Software for high-resolution single-particle cryo-EM with non-uniform ice - M. Olek, P. Zhang et al

PubReading [102] - Brain charts for the human lifespan - R. Bethlehem, J. Seidlitz, A. Alexander-Bloch et al

PubReading [101] - Glycemic control in the critically ill: Less is more - G. Alhatemi, B. Seyoum et al

PubReading [100] - The complete sequence of a human genome - S. Nurk, S. Koren, A. Rhie, A. Phillips et al

PubReading [99] - MicroED: conception, practice and future opportunities - M. Clabbers, A. Shiriaevaa and T. Gonen

PubReading [89] - Immunotherapy and prevention of pancreatic cancer - A. Morrison, K. Byrne and R. Vonderheide

PubReading [97] - Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool’s Gold? - J. Wilson, K. Petersson et al.

PubReading [96] - Highly accurate protein structure prediction for the human proteome - K. Tunyasuvunakool, D. Hassabis et al.

PubReading [95] - A safe lithium mimetic for bipolar disorder - N. Singh, G. Churchill et al.

PubReading [94] - Tissue architecture in tumor initiation and progression - J. Almagro, A. Behrens

PubReading [93] - Neuroprotective Actions of Dietary Choline - J. Blusztajn, B. Slack and T. Mellott

PubReading [92] - Progress toward understanding chromosome silencing by Xist RNA - N. Brockdorff, J. Bowness, and G. Wei

PubReading [91] - Circular Dichroism Spectroscopy of DNA: From Duplexes to Quadruplexes - M. Vorlickova, J. Kypr et al

PubReading [90] - Functional enzyme–polymer complexes - C. Waltman, M. Olvera de la Cruz

PubReading [89] - Novel Therapeutic Target(s) for Psoriatic Disease - V. Thakur and R. Mahajan

PubReading [88] - Factors influencing self-harm thoughts and behaviours over the first year of the COVID-19 pandemic in the UK: longitudinal analysis of 49 324 adults - E. Paul and D. Fancourt

PubReading [87] - Adipocytes, Innate Immunity and Obesity: A Mini-Review - A.Blaszczak, A. Jalilvand and W. Hsueh

PubReading [86] - What is the structural chemistry of the living organism at its temperature and pressure? - J. Helliwell

PubReading [85] - Low-dose metformin targets the lysosomal AMPK pathway through PEN2 - T. Ma, S. Lin

PubReading [84] - Neurotrauma and Repair Research: Traumatic Brain Injury (TBI) and its Treatments - H. Algattas and J. Huang

PubReading [83] - CAR T cells produced in vivo to treat cardiac injury - J. Rurik, J. Epstein et al.

PubReading [82] - How to Write a Systematic Review - R. Wright, K. Spindler et al.

PubReading [80] - Exercise plasma boosts memory and dampens brain inflammation via clusterin - Z. De Miguel, T. Wyss-Coray et al.

PubReading [81] - The N-terminal cysteine is a dual sensor of oxygen and oxidative stress - A. Jung Heo, Y. Tae Kwon et al.

PubReading [79] - Nanopore sequencing technology, bioinformatics and applications - Y. Wang, K. Fai Au et al.

PubReading [78] - Megahertz serial crystallography - Max Wiedorn et al.

PubReading [77] - Engineering transplantable jejunal mucosal grafts using patient- derived organoids from children with intestinal failure - M. Laween, V. Li et al.

PubReading [76] - The Catalytic Asymmetric Intermolecular Prins Reaction - D. Díaz-Oviedo, R. Maji, and B. List

PubReading [74] - Sodium/glucose cotransporter 2 (SGLT2) inhibitors improve cardiac function by reducing JunD expression in human diabetic hearts - R. Marfella, G. Paolisso et al.

PubReading [73] - Electronic health records and polygenic risk scores for predicting disease risk - R. Li, J. Moore et al.

PubReading [72] - Delivery strategies for macromolecular drugs in cancer therapy - Q. Guo, C. Jiang et al.

PubReading [71] - Optical Microscopy and Electron Microscopy for the Morphological Evaluation of Tendons: A Mini Review - M. Xu, B. Liu et al.

PubReading [70] - Flavonoids as Anticancer Agents - D. Kopustinskiene, J. Bernatoniene et al

PubReading [69]- Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection - A. Di Pietro, K. Good-Jacobson et al

PubReading [68] - Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ - E. Draper and H. Roche

PubReading [67] - DNA methylation in human sperm: a systematic review - F. Asenius, A. Danson and S. Marzi

PubReading [66] - The 2021 Nucleic Acids Research database issue and the online molecular biology database collection - D. Rigden and X. Fernandez

PubReading [65] - Cell Cycle Regulation of Stem Cells by MicroRNAs - M. Mens and M. Ghanbari

PubReading [64] - Lysosome-targeting chimaeras for degradation of extracellular proteins - S. Banik, C. Bertozzi et al

PubReading [63] - Integrated analysis of multimodal single-cell data -Y. Hao, R. Satija

PubReading [62] - Molecular Printing with DNA Nanotechnology - F. Rizzuto, T. Trinh and H. Sleiman

PubReading [61] - Discovery of a novel pseudo β-hairpin structure of N-truncated amyloid-β for use as a vaccine against Alzheimer’s disease - P. Bakrania, T. Bayer et al

PubReading [60] - DNA helicases in homologous recombination repair - D. Branzei and B. Szakal

PubReading [59] - Complexities of Viral Mutation Rates - K. Peck & A. Lauringa

PubReading [58] - Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing - X. Xu, L. S. Qi et al.

PubReading [57] - Obesity and hypertension - G. Seravallea and G. Grassi

PubReading [56] - Hypertension and cardiovascular risk: General aspects - S. E. Kjeldsen

PubReading [55] - Protein phase separation and determinants of in cell crystallization - C. N. Mudogo, C. Betzel

PubReading [54] - The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives - S. Tsalamandris, D. Tousoulis et al

PubReading [53] - Molecular targeted therapy of glioblastoma - E. Le Rhun, M. Weller et al.

PubReading [52] - Choosing the Method of Crystallization to Obtain Optimal Results - L. Govada and N. E. Chayen

PubReading [51] - p53, cancer and the immune response - J. Blagih, M. D. Buck and K. H. Vousden

PubReading [50] - Ki-67 gene expression - S. Uxa, K. Engeland

PubReading [49] - Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy - J. Karges, G. Gasser et al.

PubReading [48] - Induction of ubiquitin C (UBC) gene transcription is mediated by HSF1: role of proteotoxic and oxidative stress - M. Bianchi, M. Magnani et al.

PubReading [47] - Renal artery aneurysms - D. M. Coleman and J. C. Stanley

PubReading [46] - DNA-mediated engineering of multicomponent enzyme crystals - J. D. Brodina, C. A. Mirkin et al.

PubReading [45] - Built-In Active Microneedle Patch with Enhanced Autonomous Drug Delivery - M.A. Lopez-Ramirez, J. Wang et al.

PubReading [44] - I-motif DNA structures are formed in the nuclei of human cells - M. Zeraati, D. Christ et al.