All Episodes
The Optispan Podcast with Matt Kaeberlein — 168 episodes
Neuroscientist Reveals What's Actually Working for Brain Longevity (with Dr. Tommy Wood)
Longevity Doctors Rank the Most Hyped Supplements (AMA with Dr. Kaeberlein and Dr. Byrne)
New Discovery: This Test Finds Cancer Before It Even Exists (Reaction to Galleri Trial)
The Best Women’s Health Tips on the Planet with Dr. Jennifer Pearlman
THIS Helps Detect Heart Disease Before It Happens
RFK Jr and Joe Rogan's Peptide Claims: Longevity Expert Reacts
Optispan Success Story: What 18 Months of Real Biomarker Data Actually Looks Like (With Carlos Pinto)
Why Some Doctors Are Breaking Rules To Prescribe Peptides
How Fighting Gives You A Bulletproof Mind with Noah Neiman
Dr. Matt Ranks Longevity Supplements: The Winners and Total Scams
Optispan Success Story: How I Got Strong Without Living at the Gym
The New Food Pyramid (A Step In The Right Direction)
What Peter Attia Got Right About Ultimate Health (Rapidfire)
Everything I do for Healthspan (and why I skip THESE Supplements)
This Viral "Whorebath" Test Is Not What You Think It Is
Preventive Failure: How Modern Healthcare Misses Disease Early
6 Months on TRT Changed My Body (THIS Is My Takeaway)
The Dangerous Truth About The Peptide Craze (I Tried It)
New Discovery: This Molecule Could Beat Rapamycin in Longevity
Matt's Thanksgiving Message
Longevity Problem: 70% Of All Deaths Are Caused By Aging - Dr. Andrew Steele
Scientist Reacts: Why Megadosing Creatine Is A Waste Of Time
We'll Pay $101 Million If You Prove You Can Reverse Aging
Dr. Stanfield Mortgaged His House For $150k To Prove Longevity Drug Works
Don't Fall For This Scam: Matt's Deepfake PSA
You Might Have The Heart Attack Gene. Here Are The Signs
The $40 Cure They Don't Want You to Know About
Longevity Lie: Doctor Reveals Why Anti-Aging Supplements Don’t Work
Blood Cleaning: Cuts Age Biomarkers 2.6 Years in 90 Days!
Doctor Reveals: The Dark Side of the Longevity Industry
Why 400+ Alzheimer's Drugs Failed (Here's What Works)
Female Biohacker: Why Women Need Different Longevity Protocols (Simple Steps)
AI Medicine: ChatGPT Reads Blood Tests Faster Than Your Doctor
Is Creatine Harming Your Kidneys? The Blood Test Myth Explained.
Elite Performance: How Pro Athletes Use HRV to Train Smarter (Not Harder)
Magic Mushrooms: The Next Anti-Aging Drug?
A Scientific-Backed Discussion On Fighting Cognitive Decline
Debunking 10 Longevity Myths You Still Believe | 126
Inside the Offshore Clinics Developing Gene Therapy to Fight Aging | 125
Testosterone, Rapamycin & Diet Myths: A Scientist's AMA | 124
A Geroscience Roundtable: de Grey, Kennedy & Kaeberlein on the Path to Longevity Escape Velocity | 123
Longevity Conference Attendees Hospitalized After Using Peptides? | 122
I'm Taking TESTOSTERONE: My Story, Mistakes & Insights From a Longevity Perspective | 120
A Physicist's Radical Theory of Why We Age
Doctors Reveal Their Blueprint for Lifelong Health (4 Pillars & Key Blood Tests) | 118
Rapamycin Improves Autophagy? | Analyzing Longevity News | 117
Ask a Longevity Scientist: Testosterone, "Miracle" Supplements & Falling for the Hype | 116
Scientist Fact-Checks Controversial Medical Takes: Dr. Mike React
Gut Microbiome Expert: The HIDDEN Side Of Health You're MISSING | Dr. Sean Gibbons | 114
LiveLong Conference: Takeaways on Longevity Science & Hype | 113
This Simple Test Can Reveal Your Risk Of Heart Disease | 112
The Hidden Health Toll Of Grief (and the 4 Tasks that Actually Work). | Emma Payne | 111
Rapamycin: The Worst Longevity Idea Ever Conceived? | 110
Siim Land: Biohacking Longevity, Health Span Truths & Cutting Through the Hype | 109
The Science of Aging Well: "A Practical Approach to HealthSpan Medicine" | 108
Longevity Experts Discuss Their Health Advice & Approach | Dr. Marcus Ranney & Dr. Brian Kennedy | 107
Brain Aging & Alzheimer’s Prevention: The Future of Cognitive Health Testing | Dr. Christin Glorioso | 106
Gut Health: Science-Backed Tips For Leaky Gut, IBS, & Your Microbiome | Dr. Mary Pardee | 105
The Truth About Biological Age Tests | 104
Dr. Kevin White: Concierge Medicine & Its Impacts On Living Longer & Healthier Lives | 103
Thomas Delauer: NEW Nutrition, Exercise, and Mindset Shifts In 2025 | 102
My Biggest Health & Longevity Breakthroughs at 54 | 101
Dr. Greg Fahy: Thymus Regeneration & Boosting The Immune System For Longevity | 100
The Benefits Of Testosterone Replacement Therapy (TRT) For Men - Dr. Kevin White | 99
The Effects of Rapamycin on APOE4 Carriers & Brain Function | 98
Crypto-Powered Science: How Blockchain & DAOs Are Reimagining Longevity Research | 97
Peter Attia: Training, Eating & Optimizing To Live Longer & Healthier In 2025 | 96
These Supplements Help Dogs Live Longer? | 95
Aging "Hotspot" Found in Brain? Hypochondriacs Don't Live as Long? | 94
Correcting the Record on Past Videos: Biological Age Tests, Full Body MRI's & More | 93
LIVE AMA: Longevity Scientists Answer Your Health & Longevity Questions LIVE | 92
My Review of Peter Attia’s AMA: What I Agree & Disagree With | 91
Longevity Scientists Answer 30 MORE of Your Health & Longevity Questions | 90 PART 2
MEGA Q&A: We Answer 30 of Your Health & Longevity Questions | 90 PART 1
I Got a Full Body MRI: IS IT WORTH IT? I Share My Results | 89
Understanding Women's Hormonal Health, Hormonal Changes & How Hormone Replacement Therapy Can Help | 88
Longevity Scientist On Ethan Klein's "Revolutionary New Drug For Dogs" Discussion (H3 Podcast) | 87
Epigenetic & Glycan Age Tests Results: Are Biological Age Tests Accurate? | 86
Cold Plunge & Brown Fat, Different Types of Stress, and The Power of The Mind | 85
Bryan Johnson Stopped Taking THIS & It DOESN'T Make Sense... | 84
Doctor of Naturopathy: Microbiome & SIBO, Platelet-Rich Plasma Therapy, BPC-157, Dieting Advice | 83
I Took 4 Different Biological Age Tests & Compared the Results... | 82
Dr Seager: Rethinking Health for Longevity | 81
Death, Grief, & Purpose from a Longevity Science Perspective | 80
Nutrition Myths, Gut Fixes, Natural Health Tips from a Doctor of Naturopathy | 79
We are Keeping People Sick Longer - We Need Medicine 4.0 | 78
The Probability of Us Living to Be Much Older? | 77
Longevity Scientist Answers Burning Questions About Health Trends | 76
Brain Repair: The Ketamine Combo Treatment for Depression and Chronic Pain | 75
GLP-1 Agonists Could Delay Aging? Scientist Weighs-In | 74
Anti-Aging Enthusiasts are Taking this Pill to Extend Their Lives? | 73
Brain Disorder Expert: Preventing Alzheimer's & Brain Disorders with LITHIUM | 72
Don't Drink Your Coffee First Thing in the Morning? | 71
Metformin Decelerates Aging Clocks & Slows Brain Aging? We Take a Look. | 70
Does Plant Protein Slow Your Aging? | 69 - Longevity This Week #12
The Dog Aging Project that aims at Helping Dogs Live Longer | 68 - DAP #2
You Should Focus on THESE 4 Things for Your Health & Longevity | 67 - HSM #9
NEW PEARL Trial Results: Your Questions Answered on Aging with Rapamycin for Longevity | 66 - AMA #5
Mike Mutzel on Choosing YOUR Supplements, Cholesterol & Social Health | 65 - High Intensity Health
This Study Says IL-11 Inhibitor Drug May Extend Lifespan | 64 - LTW #11
Trametinib & Rapamycin = Greater Effect on Lifespan? We Take a Look. | 63 - LTW #10
Matt Kaeberlein reflects on "David Sinclair’s Longevity Lie" | 62 - Longevity Reacts #5
Does NMN Actually Increase VO2 MAX? | 61 - Longevity This Week #9
The Horribly Under-Researched Science of Menopause, Ovarian Aging & HRT | 60 - Jennifer Garrison
Trying Cold Plunge & Sauna w/ Mike Mutzel (Risks & Benefits Discussion)| 59 - Field Trip #1
Responding to Comments that Disagree with Us on Longevity | 58 - Correcting the Record #1
Scientist Reacts to Greg Doucette's Controversial Take on DEXA Scans | 57 - Longevity Reacts #4
Most Longevity Experts Don't Tell You This About Aging | 56 - Longevity Science #8
Scientists Debate How to Live Longer & Longevity Drugs | 55 - Charles Brenner
This Company's New Longevity Senolytic Drug & The Drug Development Process | 54 - David Scieszka
A Longevity Breakthrough w/ Yamanaka Factor "Rejuvenation Cocktail?" | 53 - Longevity Reacts #3
The Benefits of Protein Restriction, How Protein Affects Hormones & FGF21 | 52 - Cristal Hill
Longevity Scientist Critiques Mike Israetel's "Exercise Scientist Critiques" | 51 - Longevity Reacts
Longevity Scientist Reacts to Bryan Johnson's "I Edited My DNA To Live Forever" |50-Longevity Reacts
Stem Cells, Aging Hallmarks & Rapamycin | 49 - Kevin White
DNA Damage, Senescence & Apoptosis | 48 - Aditi Gurkar
Answering Questions on Gold Standard Longevity Intervention RAPAMYCIN | 47 - AMA #4
Debating a Doctor's Statement on NR & Rapamycin | 46 - X-Wars
Scientists Discuss Longevity Interventions & Optimisms | 45 - K-Lab Reunion
Why Drinking a Banana Smoothie IS the Same as Eating a Banana | 44 - Longevity this Week #8
How Pregnancy Affects Aging, New Model Organisms for Aging Research, HRT | 43 - Berenice Benayoun
Solving the "Lack" of Anti-aging Discovery & Ranking Current Interventions | 42 - Mark McCormick
The UNEXPECTED Ozempic Weight Loss Body Scan Results (DEXA) | 41 - HSM #8
The Two New Highest Ranked Compounds For Lifespan Extension According to the ITP | 40 - LTW #7
Supplement Industry Secrets: What They Aren't Telling You About NAD+ & NMN | 39 - George Sutphin
Your Dog Needs Your Help. | 38 - The Dog Aging Project
Answering Your Questions on Longevity | 37 - Ask Matt Anything #4
Is This The Best Time to Work Out? | 36 - Longevity This Week #6
The Surprising Way Body Size Relates to Lifespan | 35 - Longevity Science #7
DON'T Take Resveratrol Until You Watch This Video | 34 - Healthspan Medicine #8
How He TRANSFORMED His Health by Taking Accountability. | 33 - Healthspan Journey #1
The Best Strategies for Living Longer RANKED: Longevity Tier List | 32 - HSM #7
Comparing Bryan Johnson's RAPAMYCIN DATA: INTERESTING RESULTS | 31 - R-Files #5
Reversing Biological Age: Have we finally found the answer?? | 30 - LTW #5
AI vs Aging: Why Wormbot-AI is the secret weapon against disease | 29 - Mitchell Lee
Aging Expert Explains How Healthcare got it ALL WRONG. | 28 - HSM #6
Inside this Non-profit's AMAZING Strategy to Fight Aging | 27 - Dylan Livingston
Guess his body fat percentage | #26 - Healthspan Medicine #5
How "light-sensitive" proteins are being used to fuel scientific discovery | 25 - Brandon Berry
Doctors overlook how significantly this impacts your health. | 24 - HSM #4
These 14 Medications are linked to lower death rates in humans | 23 - Longevity this Week #4
“Zombie” Senescent cells may play HUGE role in LIVING LONGER, Here's How: | 22 - Natalia Mitin
The Importance of Body Composition & Ways YOU can measure it | 21 - HSM #3
Answering Your Questions on Rapamycin: Optimal doses, tests, & stacks | 20 - AMA #3
Does this Dog Supplement Really Work to REVERSE AGE? (PART 2) | 19 - Longevity This Week #3 (2/2)
Does this Dog Supplement Really Work to REVERSE AGE? | 19 - Longevity This Week #3
Rapamycin's SURPRISING Effects on Aged IMMUNE SYSTEMS | 18 - RF #4
People are GETTING THIS WRONG about Supplements & My Supplement List | 17 - Healthspan Medicine #2
CAR T Cells: The Ultimate Anti-Aging Solution? | 16 - Longevity This Week #2
Current Healthcare ISN'T CUTTING IT: How Optispan is REVOLUTIONIZING it |15 - Healthcare Medicine #1
Longevity Science 2024: New Insights on "The Hallmarks of Aging" & What They Mean | 14 - LS #5
Matt Kaeberlein's ALLERGIC REACTION to Medication While on Longevity Drug Rapamycin | 13
Uncovering New Longevity Research DISCOVERIES: The Power of 3HAA Revealed | 12 - George Sutphin
Transforming Our Understanding of Healthcare Through Geroscience | 11 - LS#4
What a 93-Year-Old Rowing Champion Can Teach Us About Aging Well | 10 - Longevity this Week #1
Biological Age & what it REALLY means | 9 - Longevity Science #3
Rapamycin's possible SIDE EFFECTS & BENEFITS | 8 - RF#3
Off-Label Rapamycin Experiences & Doses | 7 - RF#2
Dentist Reveals Exciting Research Findings Involving Rapamycin on Oral Health | 5 - Jon An, DDS, PhD
Rapamycin's Impact on Oral Health & its Relationship to Aging (Part 2)
An introduction to the study of RAPAMYCIN | 6 - R-Files w/ Matt Kaeberlein
Rapamycin's Impact on Oral Health & its Relationship to Aging | 5 - Jonathan An, DDS, PhD
Longevity Expert Matt Kaeberlein Exposes Common Myths Circulating the Media | 4 - Nick Arapis
Longevity Expert Sheds Light on common MISCONCEPTIONS for People's' Health | 3 - Nick Arapis
Flaws in the Healthcare System, Preventative Medicine, and Next-Gen Healthcare (Part 3)
Flaws in the Healthcare System, Preventative Medicine, and Next-Gen Healthcare (Part 2)
Flaws in the Healthcare System, Preventative Medicine, and Next-Gen Healthcare | 2 - Kevin White, MD
Q&A with Scientist Matt Kaeberlein about Longevity and Living Longer | The Optispan Podcast EP 1