PODCAST · health
Itchy and Bitchy
by Karen Nickell
Nurse practitioner Karen Nickell discusses the realities of menopause and the female midlife in a way that is both informative and fun.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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215
Estrogen Has Been Let Out of Jail!
Karen is joined by future Itchy and Bitchy hosts Stephen Miller, an acute care nurse practitioner specializing in cardiovascular disease, and Dr. Keith Hnilica, a veterinary dermatologist, for a wide-ranging conversation about estradiol and hormone replacement therapy. They discuss the recent removal of the FDA black box warning from most menopausal hormone therapy products and the long shadow of the Women’s Health Initiative study.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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214
Dining with Your Dog: No Kibble Needed
Family nurse practitioner Karen Nickell introduces future Itchy and Bitchy host Dr. Keith Hnilica, a veterinary dermatologist, for a lively conversation about pet food and what animals can teach us about wellness. They dig into GLP-1 drugs for pet obesity, the links between processed kibble, gut inflammation, and skin issues, why fresh or Mediterranean-style diets may be better for dogs.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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213
Can Heartbreak Physically Break Your Heart?
Karen kicks off a new chapter for Itchy and Bitchy by introducing future host Stephen Miller, a cardiology nurse practitioner, for a conversation on Takotsubo cardiomyopathy, or “broken heart syndrome.” Together they explain what this stress-triggered heart condition is, why it so often affects postmenopausal women, and what recovery can look like.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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212
Vaginal Biofilm: Stranger Than Fiction!
Karen answers a listener's question about vaginal biofilms. What are they and why do they make recurrent BV and yeast infections so hard to treat? She explains how these bacterial or fungal communities form protective layers that resist standard treatment, reviews options that may help break the cycle and looks at at-home microbiome testing.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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211
How to Reset Distress to Peace and Joy (RERUN)
Karen shares a collection of grounding techniques to help listeners manage stress, anxiety, and negative emotions. From holding ice, savoring food, and taking mindful walks to laughter, music, anchoring exercises, the 5-4-3-2-1 method, and even the calming power of pets, Karen offers tools to help listeners return to the present moment, ease stress, and reconnect with a sense of safety and calm.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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210
AI in Medicine: Friend or Foe?
Karen explains how AI is already being used in healthcare, from helping find polyps during colonoscopies to speeding documentation. She also covers the biggest concerns, including the possibility of errors, bias, privacy risks, and over-reliance.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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209
Digital Health: The New Wild, Wild West
Karen unpacks the fast-growing world of digital health, from Apple Watch and smartphone apps to telehealth and new hospital tech that can improve care and streamline recovery at home. She also addresses the downsides, raising concerns around the security of these technologies.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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208
Healing After Pet Loss: A Personal Tale
Karen shares a deeply personal episode on the human-animal bond after the loss of her family’s lovebird, Saki, exploring why pet grief can feel so profound and practical ways to heal. She offers suggestions, from letting yourself feel what you feel to creating memorial rituals, revisiting joyful memories, and caring for your body while you mourn, plus when to seek professional support.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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207
Grandmothers Rule: Menopausal Mammals Revisited
Karen Nickell revisits menopausal mammal, this time with brand new context: new research from Uganda’s Ngogo chimpanzees shows some chimps experience menopause too. She explains what makes humans evolutionary outliers, unpacks the grandmother hypothesis, and explores why certain toothed whales (like orcas) stop reproducing yet continue to live for decades.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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206
GLP-1: Not Just a Weight Loss Med
Karen takes a look at GLP-1 receptor agonists, best known for weight loss and diabetes. She explores the rapidly expanding list of conditions these medications may help treat. From emerging and sometimes conflicting research on Parkinson’s and Alzheimer’s disease to FDA-approved benefits for cardiovascular health, kidney disease, and fatty liver disease, Karen breaks down what the science currently shows and where caution is still needed.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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205
Countdown of Karen's Top Ten Episodes of 2025
Karen counts down her top 10 Itchy & Bitchy moments of 2025, from smarter New Year’s resolutions and promising UTI vaccines on the horizon to updated insights on HRT.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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204
Oh, Snap! Osteoporosis!
Karen shares her personal journey with osteoporosis. What distinguishes it from osteopenia? How are DEXA T-scores interpreted? Why does early screening matter? She covers lifestyle and nutrition, hormone considerations, and medication options.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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203
Red Light Under My Christmas Tree?
Karen breaks down red light therapy (photobiomodulation) and where it actually helps: smoothing signs of aging, supporting hair regrowth, calming acne (especially paired with blue light), easing chronic pain and inflammation, and even emerging research for cognition in dementia.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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202
Holiday Heart Doesn't Mean a Happy Heart (RERUN)
Family nurse practitioner Karen re-airs a timely episode on “holiday heart syndrome,” the spike in alcohol-triggered arrhythmias (often AFib) that can strike otherwise healthy people during festive gatherings. She explains what binge drinking looks like, key symptoms to watch for (from palpitations and chest pressure to shortness of breath), why it raises stroke risk, and simple prevention steps.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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201
Surprising Update on Healthcare Self Advocacy!
After listening to an episode of Itchy and Bitchy, a woman pushed for further testing and caught grade 1A ovarian cancer early—requiring only surgery. Karen revisits why self-advocacy saves lives, translating expert definitions into everyday guidance and offering practical steps: build a true partnership with your provider, keep detailed symptom and medication notes, ask clear questions about tests, risks, and costs, use reliable resources (not “Dr. Google”), consult your pharmacist, and keep your advance care planning up to date.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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200
Estradiol and Skin: The Perfect Match!
Karen tackles a common menopause question: oral vs. topical estradiol. She explains first-pass metabolism and why transdermal options can lower clot, gallstone, and side-effect risks for many, then compares real-world choices.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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199
Redefining Lithium with Low Dosing
Karen tackles a listener question about low-dose lithium. She reviews micro- vs. low-dose ranges, discusses forms like lithium orotate/aspartate and third-party-tested supplement options, and flags safety essentials such as toxicity symptoms, thyroid/kidney considerations, and when to loop in your clinician.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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198
Blood Tests for Multiple Cancers + Whole Body Scan Info
In this update to the August 2024 episode, Karen explains the surge of direct-to-consumer “whole-body” MRI/CT screenings and how to decide with your provider whether they’re a good fit. In the re-aired episode, Karen explores the Galleri test, a multi-cancer early detection (MCED) blood test that can identify over 50 types of cancer. She explains how the test works, its potential benefits, and the risks associated with its use. She also shares personal stories from individuals who benefited from the test, while discussing ongoing research to determine its effectiveness in improving cancer outcomes.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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197
BPC-157: What Are You Really Buying?
Karen takes a look at BPC-157, the buzzy peptide touted for faster healing and joint relief, explaining what animal studies actually show, the lack of human clinical trials, and its regulatory reality.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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196
Getting to the Point: Microneedling Reviewed
Karen demystifies the popular skincare treatment known as microneedling. She explores how this minimally invasive procedure stimulates collagen and elastin production to improve skin texture, reduce wrinkles, and help with scars and stretch marks. She compares professional treatments with at-home devices, explains the pros and cons of each, and provides detailed guidance on safe at-home use.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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195
Unpacking Your Eye Bags
Karen tackles the puffy eye predicament that's turning well-rested people into walking advertisements for concealer. From the cruel reality of aging to your body's dramatic reaction to that late-night pizza binge, Karen breaks down the reasons your under-eyes are staging their own little rebellion.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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194
GLP-1 Meds & Hair Loss: Skinny and Bald Not the Look You're Going For?
Karen tackles the surprising link between GLP-1 medication (like Ozempic and Wegovy) and hair loss. As more people turn to these drugs for diabetes and weight management, some are left wondering: is the price of shedding pounds also shedding your hair? Karen explores possible causes behind this side effect, including rapid weight loss, nutritional deficiencies, and hormonal changes, and shares science-backed strategies to help prevent or reduce hair thinning while on these medications.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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193
How to Keep Your Cool as the World Heats Up (RERUN)
Karen shares potentially life-saving advice for staying safe in extreme heat as record-breaking temperatures sweep across the country. She explains how heat exhaustion and heat stroke develop, how to recognize early warning signs, and what to do if you or someone else is affected.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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192
Methylene Blue: What Is It Really?
Karen unpacks the hype surrounding methylene blue, a vivid cobalt dye that's gained popularity as a trendy wellness supplement. From its historical use as a textile dye and medical treatment to modern claims about boosting brain power, energy, and longevity, Karen breaks down what the science actually says—and what it doesn’t. With potential risks ranging from drug interactions to serotonin toxicity, she urges listeners to think twice before adding this unregulated supplement to their daily routine.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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191
Face Taping: Karen's Mom is Loving This!
Karen breaks down the growing trend of face taping as a non-invasive approach to reducing wrinkles and lifting sagging skin. She explains the difference between aesthetic taping for red carpet-ready lift and overnight wrinkle patches like Frownies that aim to retrain facial muscles. Karen walks listeners through product options, techniques, and safety tips—while sharing her own experiences (and her mom’s timeless advice) about fighting the dreaded “11s.”Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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190
Presto Chango: Hormone Precursors
Karen breaks down the benefits of precursor hormones—specifically pregnenolone and DHEA—for those who struggle with traditional hormone replacement therapy. She explains how these naturally occurring compounds support the production of estrogen, progesterone, and testosterone, and how they may offer relief from symptoms like brain fog, fatigue, sleep disturbances, and low libido.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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189
Cancer in Young Adults: What in the World is Happening?
Karen addresses the troubling rise in early-onset cancers among adults under 50, particularly women. Drawing on the latest research, she discusses contributing factors—from delayed screenings and family history to gut health, environmental exposures, and systemic inflammation. Karen also highlights how current healthcare gaps, lifestyle factors, and even prenatal influences may be playing a role in this growing health crisis.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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188
The Hormone Makeover with Donna White
Karen welcomes Donna White, a leading expert in bioidentical hormone replacement therapy (BHRT) with over 30 years of experience. They discuss the myths and truths about hormone therapy, the critical role of proper testing and individualized treatment plans, and how BHRT can drastically improve quality of life for women in menopause and beyond. Donna shares her personal journey with hormonal imbalance, her mission to train providers across the country, and practical advice for finding a knowledgeable, well-trained BHRT provider.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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187
Hormones and High Notes
Karen unpacks the surprising connection between hormones and the human voice—especially for singers. Drawing from her dual background in opera and medicine, she explains how hormonal shifts throughout the menstrual cycle can impact vocal quality, flexibility, and range.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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186
Scalp Cooling to Spare Your Hair During Chemotherapy
Karen shares how a friend's breast cancer diagnosis became a powerful example of self-advocacy in action. From discovering she didn’t need chemotherapy after requesting additional testing, to researching scalp cooling treatments and skin protection during radiation, this story highlights how knowledge and persistence can lead to better care. Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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185
The Best Health Advocate is YOU!
Karen shares a powerful listener story about self-advocacy in healthcare and how trusting your instincts can be lifesaving. After experiencing persistent symptoms that were initially dismissed by a doctor, this listener took charge of her health, sought a second opinion, and ultimately discovered a serious diagnosis.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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184
Menopause and HPV (Part 2 of 2)
Karen continues her discussion on HPV, focusing on the types of cancers it can cause and the best prevention methods. She breaks down the staggering statistics on HPV-related cancers, explains why the virus can remain dormant for decades, and highlights the importance of screening and early detection.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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183
Menopause and HPV (Part 1 of 2)
Karen unpacks the risks of HPV for women in their perimenopausal and menopausal years. She explains how the virus spreads, why it can re-emerge decades after initial exposure, and how hormonal and immune system changes impact its persistence.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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182
Iodine: This Element is Elemental!
Karen explores the importance of iodine and how its deficiency can impact overall health. She discusses the essential role iodine plays in thyroid function, metabolism, and cognitive development, particularly in pregnant women. Karen explains why iodine deficiency is on the rise, how to test for it, and the best ways to ensure adequate intake through diet and supplements.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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181
Not Another UTI! Help on the Horizon
Karen explores the potential of UTI vaccines as an alternative to antibiotics for treating recurrent urinary tract infections. She explains how UTIs develop, why traditional antibiotic treatments often fail, and how vaccines work to boost the body's immune response.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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180
Love Your Liver? Think Twice Before Starting Kava for Anxiety
Karen examines the use of kava supplements, exploring their potential benefits for anxiety and their serious risks, including liver toxicity. She highlights key studies on kava's effectiveness, explains its traditional use, and warns of its interactions with medications. She also shares a list of alternative supplements that have been shown to help with anxiety and depression without the significant risks associated with kava. Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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179
2025 Resolutions: Karen Has One, Do You?
Karen kicks off 2025 by examining the science behind New Year's resolutions. She explores why we make them, who is most likely to set goals for the new year, and the reasons resolutions often fail. She also shares practical tips for improving success rates, such as setting small, meaningful goals, using habit trackers, and practicing self-compassion after setbacks.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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178
The Great Undies Debate
Karen settles the great debate: should you sleep with or without underwear? She explores the health benefits and potential drawbacks of both choices. From reducing the risk of infections to promoting vaginal health, she provides research-backed insights to help you make the best decision for your body.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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177
Baby, It's Cold Outside: What to Know About Cold Related Illness
Karen discusses the dangers of cold-related illnesses and how to stay safe during the winter months. She explains the causes, symptoms, and prevention strategies for conditions such as hypothermia, frostbite, chillblains, and trench foot. Learn practical tips for dressing warmly, avoiding prolonged exposure to cold, and recognizing early warning signs of these conditions to prevent severe complications.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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176
A Vagina Day! Beating Bacterial Vaginosis
Karen addresses bacterial vaginosis (BV), a common vaginal infection that affects many women. She explains its symptoms, causes, and risk factors, while offering practical solutions for both treatment and prevention. From prescription antibiotics to boric acid suppositories and probiotics, Karen shares a comprehensive approach to managing recurrent BV.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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175
How to Reset Distress to Peace and Joy
Karen shares a collection of grounding techniques to help listeners manage stress, anxiety, and negative emotions.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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174
Sore Tongue or Cracked Lips? Might Be Iron Deficiency Anemia
Karen sheds light on iron deficiency anemia, covering its causes, symptoms, and treatment options. She explains the stages of anemia development, common risk factors, and how to recognize signs like fatigue, pale skin, and brittle nails.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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173
HRT Pellets: A Pain in the Butt or a Perfect Fit?
Karen discusses hormone pellet therapy, one form of bioidentical hormone replacement that is designed to produce consistent, long-term hormone levels. She outlines how these tiny pellets are inserted under the skin and can be used to minimize the symptoms of menopause and hormone imbalance—exploring the benefits, possible side effects, and risks associated with them. She also gives tips on what to expect with the treatment and suggestions for finding a trusted provider.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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172
Inositol – It Helps Mood & Metabolic Problems
Karen takes on the topic of inositol supplements, particularly their benefits for managing metabolic and mood disorders. She explores the science behind inositol, a substance naturally found in the body, and how it can support insulin regulation and neurotransmitter balance.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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171
Magnesium Mix-up: So Many Choices! (RERUN)
Karen answers the question: "What type of magnesium should I take if I decide to take a supplement?" She explains magnesium's essential role in health, touching on its benefits for brain, heart, and muscle function, and highlights the widespread issue of magnesium deficiency, often due to processed food diets.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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170
Karen Tells All About How to Improve That Saggy, Wrinkled Face
Karen covers the topic of estrogen loss during perimenopause and its effects on skin health, particularly facial skin. She explores how declining estrogen levels lead to reduced skin elasticity, collagen loss, and increased dryness, and discusses the benefits of using topical estrogen creams to counteract these effects. She also reviews the history of estrogen in skincare, recent studies on its effectiveness, and shares her own experience with adding estrogen cream to her facial care regimen.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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169
Blood Test for Multiple Cancers: Yup, It Exists!
Karen explores the Galleri test, a multi-cancer early detection (MCED) blood test that can identify over 50 types of cancer. She explains how the test works, its potential benefits, and the risks associated with its use. She also shares personal stories from individuals who benefited from the test, while discussing ongoing research to determine its effectiveness in improving cancer outcomes.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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168
There's No Hocus-Pocus to Get Focus
You have a limited offer you can use now, that gets you up to 48% off your first subscription or 20% off one time purchases with code ITCHY20 at checkout. You can claim it at: https://magicmind.com/itchyKaren explores the topic of improving focus and concentration, sharing research-backed methods to help listeners sharpen their mental clarity. From brain training games like Sudoku and crossword puzzles to the benefits of regular exercise and proper sleep, Karen provides practical tips for enhancing cognitive function.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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167
Debunking TikTok Trends: Garlic Cloves Up the Nose?
Karen addresses the rise of medical misinformation on TikTok. She highlights the dangers of following non-factual advice from non-medical influencers, explaining the importance of consulting reliable sources and medical professionals for health advice. She also provides tips on how to identify and avoid false health claims on social media. Learn how to navigate the murky waters of TikTok health trends and protect your well-being.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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166
The Bite IS Worse Than the Buzz: Mosquito Borne Diseases (Part 2)
In part two of our series on those pesky mosquitos, Karen dives into practical measures to prevent mosquito bites and protect against mosquito-borne diseases. She explores effective repellents, proper application methods, and household tips to minimize mosquito presence. Tune in to find out how Victoria's Secret could play a role in preventing bug bites this summer.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
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ABOUT THIS SHOW
Nurse practitioner Karen Nickell discusses the realities of menopause and the female midlife in a way that is both informative and fun.Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.
HOSTED BY
Karen Nickell
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