All Episodes
Aging-US — 500 episodes · page 1 of 5
Behind the Study: Drug Combo Targets Cancer & Senescent Cells, Extends Lifespan in Old Mice
Longevity & Aging Series (S4, E7): Dr. Irina Conboy and Dr. Zachery Robinson
Editors’ Choice: Social determinants of health and risk of dementia in people with and without type 2 diabetes
New Control Theory Framework Proposes a Safer Approach to Aging Drug Discovery
New Gene–Phenotype Catalogue Maps the Genetic Landscape of Premature Aging
Targeting PLA2G15 Reduces Senescence and Alters Lipid Metabolism in Kidney Cells
Behavioral Complexity Could Offer New Insights Into Aging and Frailty
Mini-GRID Radiotherapy Reduces Senescence While Preserving Growth Inhibition in Glioma Cells
Aging Supports the 11th International Cell Senescence Association Conference
Adverse Social Determinants Linked to Higher Dementia Risk in People With Type 2 Diabetes
ATF5 Helps Preserve Mitochondrial Quality and Muscle Endurance During Aging
Developmental Senescence Emerges as a Candidate Mechanism in CHARGE Syndrome
Longevity & Aging Series (S4, E6): Dr. Adam Bohnert
Exceptional Longevity Across Species Linked to DNA Maintenance, Stemness and Stress Resistance
The “Guardian Paradox” Links Chronic DNA Damage Response to Aging
EDITORS’ CHOICE: Human-relevant Ptpn6 mutation alters immune and hepatic functions during aging
Human-Relevant Ptpn6 Mutation Reveals Complex Links Between Immunity, Metabolism and Liver Aging
Evidence for Cellular Senescence as a Driver of Aging Stronger Than for Somatic Mutations
Misha Blagosklonny’s Ideas Reshaped Thinking About Aging
Reduced Insulin/IGF-1 Signaling Dramatically Extends Male Lifespan in C. elegans
Three Herbal Extracts Protect Mitochondrial Function in a Cellular Model of Parkinson’s Disease
Behind the Study: How Aging Impairs Tuberculosis Clearance
Indy Gene Reduction Linked to Healthier Gut Microbiota and Longer Lifespan in Fruit Flies
Developmental Programs Could Help Drive the Aging Process
Higher TMAO Levels Linked to Cardiometabolic Risk and Brain Atrophy in Older Adults
Metformin Emerges as a Promising Candidate at the Intersection of Aging and Longevity
Targeting POLG Reduces Breast Cancer Stemness Through Mitochondrial Dysfunction
Aging Partners with Aging Research and Drug Discovery Meeting (ARDD) as Media Partner
EDITORS’ CHOICE: Slowing intervertebral disc aging in mice through long-term systemic treatment
Transcriptomic Aging Clock Reveals Age-Related Molecular Patterns in Opioid Dependence
Misha Blagosklonny’s Scientific Legacy Continues to Shape Modern Aging Research
Hyperfunction Theory Offers a New Perspective on Why We Age
Longevity & Aging Series (S4, E5): Dr. Kan Cao
Fatty Liver Disease Linked to Early Cardiovascular and Cognitive Changes
Hypertonic Saline Plus Furosemide Improves Heart Failure Biomarkers in Randomized Trial
New Drug Combination Targets Cancer and Senescent Cells While Extending Lifespan in Old Mice
Italy Proposes a Healthspan-Focused Framework for Healthy Aging
Senolytic PROTAC Slows Age-Related Intervertebral Disc Degeneration in Male Mice
New Surface Marker Could Advance Precision Therapies for Type 2 Diabetes
Brain Flexibility Is Linked to Hand Coordination During Aging
Preserving Peroxisomes Helps Maintain Mitochondrial Health and Extend Lifespan in C. elegans
EDITORS’ CHOICE: The multifaceted inducers of cellular senescence
Senescent Cells Found to Accumulate Lipid Droplets Across Aging and Alzheimer’s Disease
Sex-Specific Hormones Could Hold the Key to Better Sarcopenia Treatments
Longevity & Aging Series (S4, E4): Dr. Maria Blasco
Multiple Biological Triggers Shape Cellular Senescence in Aging and Disease
Plant-Based Dietary Patterns Are Associated With Slower Biological Aging
Comprehensive Individual-Patient Analysis Clarifies Life Expectancy Across Rare Progeria Disorders
Nonhuman Primate Research Reveals How Aging, Stress, Behavior May Interact to Increase Disease Risk
Cellular Senescence and Stem Cells Share a More Complex Relationship Than Previously Recognized
Lifestyle Intervention Linked to Slower Biological Aging Markers in Older Men
Researchers Identify Key Signaling Pathway Driving Muscle Cell Aging
Do Exergames Improve Mood and Mental Well-Being in Older Adults?
Childhood Adversity May Leave Lasting Biological Scars Decades Later
EDITORS’ CHOICE: Epigenetic Aging Biomarkers Respond to Exercise and Dietary Intervention
Common Aging Mechanisms May Link Vision Loss Disorder to Increased Risk of Certain Cancers
Physics Meets Aging: Researchers Lay the Foundations of Gerophysics
Aging Muscle Follows Different Genetic Programs in Mice and Humans
Blood Tests and Gut Bacteria May Help Reveal Your Biological Age
Thirty Years After Discovery of SA-β-gal: Researchers Revisit the Hallmarks of Cellular Senescence
Senescent Muscle Cells Send Molecular Messages That May Contribute to Age-Related Muscle Decline
DNA Methylation Clocks May Help Explain How Social Inequality Influences Mortality
Extending Healthspan Through Public Health and Longevity Medicine
Methylene Blue May Help Protect Hair Follicle Stem Cells from Aging and Metabolic Stress
EDITORS’ CHOICE: Epigenetic age acceleration with MRI biomarkers of aging and Alzheimer’s...
Anti-Aging Strategies Aim to Target Harmful Senescent Cells While Preserving Beneficial Ones
Glutathione Pathway May Hold the Key to Safer Anti-Obesity Interventions
Aging Immune Systems Show Reduced Ability to Clear Tuberculosis During Treatment
Large-Scale Multi-Omics Study Aims to Decode Aging in the Indian Population
Human Telomerase Shows Selective Cross-Species Activity, Revealing Limits of Animal Models
Aging-US Supports the NOVA Conference 2026
Stage-Specific Gene Expression Changes Reveal Early Triggers of Cellular Aging
P38 MAPK–Driven Epigenetic Regulation Identified as a Key Mechanism in Lung Fibrosis
From Hydra to Rotifers: A New Hypothesis Explores Pathways to Delay Aging in Humans
Epigenetic Aging Linked to MRI Signatures of Neurodegeneration but Not General Brain Aging
Global Experts Highlight Path Toward Actionable Interventions in Human Aging
Modeling Premature Aging in Yeast Reveals Key Effects of Progerin on Cellular Lifespan
Gene–Phenotype Catalogue Provides New Insights into Premature Aging Disorders
Longevity & Aging Series (S4, E3): Dr. Ricardo Costeira
Decline in Glycolytic ATP Production Proposed as a Fundamental Mechanism Limiting Lifespan
EDITORS’ CHOICE: Plant-based dietary patterns are associated with slower epigenetic aging
ATF5 Required for Maintaining Mitochondrial Homeostasis and Skeletal Muscle Health During Aging
Hypertonic Saline Plus Furosemide Linked to Lower Inflammatory and Remodeling Markers in ADHF
BOLD Variability Modulation Linked to Age-Specific Bimanual Performance
IL6 and IL6R: Opposing Forces of Inflammation That Shape Human Survival
Plant-Based Dietary Patterns Linked to Slower Epigenetic Aging
Exergames Could Improve Mood in Older Adults
New Blood- and Microbiome-Based Neural Networks Forecast Human Biological Age
Longevity & Aging Series (S4, E2): Dr. David Gems
Healthy Life Extension Positioned as Geroscience’s North Star
Mitochondrial Circular RNAs: New Players in Human Aging
Impact Journals to Participate at AACR Annual Meeting 2026 in San Diego
BSO Recapitulates Anti-Obesity Effects of Sulfur Amino Acid Restriction Without Bone Loss
P38 MAPK Linked to Epigenetic Activation of Fibrotic Genes in Senescent Lung Fibroblasts
Aging-US Editors' Choice (March, 2026)
Tictock: A Single-Cell Clock Measures Immune Aging in Viral Infections
Next-Generation Metabolic Theory Suggests Glycolytic ATP Decline May Limit Lifespan
Study Identifies Opposing Roles for IL6 and IL6R in Long-Term Mortality
Acknowledgment of 2025 Reviewers
Study Identifies Aging-Associated Mitochondrial Circular RNAs