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All Episodes

VJHemOnc Podcast — 200 episodes

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Title
1

Advances in stem cell transplantation from EBMT 2026: managing GvHD, donor selection & evolving clinical strategies

2

Myeloid Monthly: breaking news & updates from the classification advancement meeting

3

How AI is transforming hematologic oncology

4

MRD in ALL and AML: from prognostic marker to clinical endpoint

5

Nursing in CAR-T & cellular therapy: updates and insights from the EBMT-EHA CAR T-cell Meeting 2026

6

Recent BTK inhibitor trial updates across non-Hodgkin lymphoma subtypes

7

ASH 2025 highlights in AL amyloidosis: risk stratification, bispecific antibodies, CAR-T, & MRD

8

Top ASH 2025 updates in AML: redefining frontline therapy, menin inhibition, venetoclax-based triplets, & emerging immunotherapies

9

Managing and preventing differentiation syndrome in APL

10

Top ASH 2025 NHL updates: novel CAR T-cell therapies, fixed-duration strategies, evolving frontline approaches, & more

11

Top updates in myeloma from ASH 2025: the RedirecTT-1 and MajesTEC-3 trials, dual-targeting CAR-T, trispecific antibodies, and more!

12

Top CLL updates from ASH 2025: novel BTKi monotherapy and combination approaches, BTK degraders, & more

13

Top updates in MDS from ASH 2025: key trial updates and debated topics

14

Sickle cell disease management: navigating the transition from pediatric to adult care, managing VOCs, & more

15

Accelerated- and blast-phase MPNs: diagnosis, management, and current challenges

16

The value and utility of MRD in the management of adults with newly-diagnosed AML

17

Updates from iwHRMM: targeted and immune-related therapies and mechanisms of resistance

18

Advances in immunotherapy for NHL: updates from iwNHL 2025

19

Reviewing recent guideline updates on the risk stratification and treatment of AML

20

The management of CLL in resource-limited settings: guideline development and ongoing projects

21

The multi-disciplinary team in CAR-T therapy: insights from a nurse, a neurologist, and a palliative care specialist

22

Understanding financial and time toxicity in cancer care: advice for community oncologists

23

Listener Q&A special: expert insights on CLL, myeloma, and lymphoma

24

Novel strategies and advances in the management and classification of MDS: insights from iwMDS 2025

25

Advances in Waldenström’s macroglobulinemia: significance of genetic alterations, current treatment strategies, & ongoing trials

26

FLT3-ITD+ AML: recent trial updates, novel approaches, and MRD

27

Extramedullary disease in multiple myeloma: biology, management strategies, & the RedirecTT-1 trial

28

iwMPN 2025 highlights: novel approaches to the upfront management of myelofibrosis, cardiovascular health in MPNs, & more

29

Managing CNS lymphoma: expert insights and updates from ICML 2025

30

iwMDS wrap-up: translating research into practice to optimize patient care

31

Targeting mutant CALR in MPNs with antibodies & cellular therapy: the potential for disease modification

32

Treating elderly or unfit patients with AML: current approach and future directions

33

Key HemOnc updates from ASCO 2025: myeloma, lymphoma, MPNs, & more!

34

CHIP & CCUS: advances in understanding and should we treat these precursor conditions?

35

Diagnosing amyloidosis: identifying early signs, appropriate diagnostic tests, and challenges that remain

36

IPIG 2025 Highlights: challenging situations in PNH, updates from the COMMODORE trials, and more

37

Recent advances in Hodgkin lymphoma treatment: novel regimens, ongoing trials & treating R/R disease

38

Gene therapy in sickle cell disease: patient selection, potential complications, & more

39

Highlights from iwCAR-T 2025: improving the efficacy and safety of CAR T-cells & access in the community

40

Updates to the ESMO CLL clinical practice guidelines and implications for relapsed therapy

41

Highlights from iwMyeloma 2025: trial updates and practical considerations

42

Updates to the ESMO CLL clinical practice guidelines: implications for frontline treatment

43

Highlights from EBMT 2025: preventing and managing GvHD, harnessing AI in transplant, & more

44

Sequencing therapies in R/R NHL: immunotherapy in DLBCL, BTKis in MCL, & more!

45

Novel CAR strategies being explored in lymphoma: allogeneic products, trispecific CARs & new manufacturing platforms

46

Approaches to optimizing induction therapy in AML: FLT3 inhibitors, menin inhibitors, CPX-351, & more!

47

Treating R/R mantle cell lymphoma: the role of BTK inhibitors, combination approaches being explored & overcoming resistance

48

Addressing unmet needs in myeloma: early detection, frail/elderly patients, triple-class exposed disease, & more!

49

CAR T-cell therapy in ALL: trial updates, novel approaches, & real-world outcomes

50

Post-ASH amyloidosis highlights: the ANDROMEDA trial, risk stratification, value of MRD, & more!

51

Post-ASH non-malignant highlights: updates in sickle cell disease, thalassemia, and hemophilia

52

Post-ASH myeloma highlights: key takeaways for community physicians & trials to look out for in 2025

53

Post-ASH AML highlights: novel approaches to frontline therapy, advances with menin inhibitors, & managing FLT3-ITD+ AML

54

Post-ASH MPN highlights: key trial updates in MF, novel approaches being explored in R/R disease, & more!

55

Post-ASH NHL highlights: novel combinations in the frontline setting and advancements with immunotherapy in the R/R setting

56

Post-ASH MDS highlights: managing anemia in LR-MDS and novel approaches to treating HR-MDS

57

Post-ASH CLL highlights: BTK inhibitors & degraders, bispecific antibodies, & more!

58

Advancing treatment for BPDCN: current therapies, a deep dive into tagraxofusp, & emerging novel agents

59

Improving care for patients with SCD: pain management, ongoing projects & unmet needs

60

Understanding BPDCN: dermatology and hematology perspectives on presentation, diagnosis, treatment, & multidisciplinary care

61

Managing complications associated with WM: Bing-Neel syndrome, acquired von Willebrand disease, & more!

62

CAR-T therapies and bispecific antibodies in the treatment of high-risk multiple myeloma: updates from iwHRMM 2024

63

The treatment landscape and challenges in rare diseases: BPDCN, CMML, MPN-AP/BP, and VEXAS

64

Exploring the role of BTK inhibitors in mantle cell lymphoma: sequencing & managing adverse events

65

An update on menin inhibition in AML from iwAL 2024: current data, mechanisms of resistance, & more!

66

CAR T-cells and bispecific antibodies in the treatment of NHL: updates from iwNHL 2024

67

Prolonging remission in AML: current approaches & future outlooks

68

A focus on the use of artificial intelligence to personalize blood cancer care

69

A focus on pediatric leukemias: trials, treatments, & challenges

70

A focus on the psychosocial impacts of living with blood cancer

71

Global perspectives on blood cancers: addressing disparities in awareness, diagnosis, and treatment

72

Insights into PV and ET: treating the AYA population, defining goals when treating patients, & more

73

Hemophilia updates from ISTH 2024: ongoing clinical trials, emerging gene therapies & remaining challenges

74

Inflammation and immune interventions in MDS: targeting STAT, IRAK4, & more

75

Updates in the treatment of SCD and thalassemia from EHA 2024: key trial updates, challenges with gene therapies & unmet needs

76

Unmet treatment needs in MF: managing prefibrotic disease & thrombocytopenia, novel agents & endpoints for clinical trials

77

The role of BTK inhibitors in MCL, ongoing trials & future outlooks: updates from EHA 2024

78

Novel developments in lower-risk MDS & important practical considerations when treating patients

79

Updates on the use of BCMA-targeting bispecific antibodies in R/R multiple myeloma: insights from EHA & ASCO 2024

80

Updates in the treatment of CLL from EHA 2024: BTK and BCL2 inhibitor combinations, BTK degraders, and more

81

Highlights from ISA 2024: the importance of early diagnosis in AL amyloidosis, trials in progress & patient selection for SCT

82

Treating LR-MDS beyond ESA failure: currently approved agents, novel approaches & future outlooks

83

BPDCN treatment and management: CD123-targeting agents, CNS involvement & approaching pediatric/AYA patients

84

The future of CAR-T therapy in lymphoma, addressing the risk of secondary malignancy & the optimal sequencing of these agents with bispecific antibodies

85

iwMyeloma 2024 Session I: approaching bone disease, clinical trial updates & the value of MRD as an endpoint in trials

86

Managing anemia in MF, key emerging trials in the UK, and approaching young patients with MPNs

87

Highlights from EBMT 2024: treating & managing GvHD & understanding the role of the gut microbiome

88

The importance of cardio-oncology: awareness around the ESC 2022 guidelines & the value of building MDTs

89

Exploring the possibility of early interception in smoldering myeloma: novel agents, challenges & advances in risk stratification

90

CHIP & CCUS: knowledge gaps, ongoing trials & recommendations for approaching patients with myeloid precursors

91

Monoclonal B-cell lymphocytosis: classification, biology and exploring the possibility of early interception

92

The impact of CAR-T therapy on the myeloma treatment landscape, patient selection for CAR-T & the evolving role of autoSCT

93

Diagnosing amyloidosis, currently available therapies & the importance of cardio-oncology

94

Addressing the importance of lymphodepletion, factors contributing to ICAHT & the cost effectiveness of CAR-T therapy

95

Updates with the use of CAR-T therapy in ALL: ongoing challenges, strategies to overcome resistance & future outlooks

96

Targeted therapy in AML: the growing role of menin inhibitors & clinical trials exploring these agents

97

Updates in lower- and higher-risk MDS: challenges, novel agents & key clinical trials at ASH 2023

98

Key updates in thalassemia at ASH 2023: gene therapies, ongoing trials & the value of precision medicine

99

Updates, challenges and novel agents being explored in BPDCN

100

Unanswered questions regarding the sequencing of BCMA therapies, the prognostic value of CTCs & the growing role of quadruplets

101

Key updates in sickle cell disease at ASH 2023: disease biology, ongoing trials & the growing role of gene therapy

102

ASH 2023 highlights: updates in the diagnosis and treatment of amyloidosis

103

MPN highlights at ASH 2023: novel agents & ongoing clinical trials in ET, PV and MF

104

iwNHL 2023 Session V: Expanding the CAR platform in NHL

105

iwCLL 2023: The role of continuous BTKis, approaching Richter’s transformation & addressing the underrepresentation of elderly patients in trials

106

iwNHL 2023 Session IV: Novel therapies in NHL: BTK inhibitors, BTK degraders, and bispecific antibodies

107

Unmet needs in AL amyloidosis, novel treatment strategies being explored, and the role of CHIP

108

iwNHL 2023 Session III: Recent updates with the use of antibody-drug conjugates in NHL

109

MPN diagnosis & treatment: novel agents in PV, clinical guidance for the use of JAK inhibitors & the growing role of combination approaches

110

iwNHL 2023 Session II: The evolving treatment landscape in mantle cell lymphoma

111

iwNHL 2023 Session I: Updates on the biology and treatment of T-cell lymphoma

112

iwAL 2023 Session IV: transplantation and immunotherapies in AML: improving patient outcomes

113

Classifying frailty and approaching elderly patients with lymphoma

114

Updates on the diagnosis, risk stratification and treatment of lower-risk MDS

115

iwAL 2023 Session III: The relevance of TP53 mutation in AML

116

iwAL 2023 Session II: Novel treatments in AML: FLT3 inhibitors, combinations, and more

117

iwAL 2023 Session I: Clonal hematopoiesis in AML, early detection and potential therapeutics

118

Applications of MRD in multiple myeloma: using MRD to guide treatment decisions

119

Exploring and comparing the curative potential of CAR-T therapy & bispecific antibodies in R/R DLBCL

120

Pre-MDS states: improving prognosis, novel therapeutic approaches, and challenges with distinguishing these conditions

121

Accelerated-phase MPNs: mutational landscape, challenges, and novel treatment strategies being explored

122

Determining the optimal sequencing of bispecifics and CAR-T cells in multiple myeloma

123

Overcoming barriers to CAR-T therapy: improving access and cost

124

The importance of addressing quality of life and improving symptom management in MPNs

125

Updates in the treatment and management of amyloidosis and the importance of the multidisciplinary team

126

Hemophilia: the current standard of care and the value of novel gene therapies

127

CLL highlights at EHA 2023: latest advances with the use of BTK inhibitors

128

Myeloma highlights at EHA 2023: CARTITUDE-4 & CARTITUDE-1 updates & the use of MRD in clinical practice

129

Lymphoma highlights at EHA 2023: sequencing bispecifics & CAR-T cells, bridging therapy & toxicity management

130

iwCAR-T Session IV: CAR-T therapy in CLL: challenges, combination approaches and ongoing trials

131

MDS 2023 highlights: managing anemia in lower-risk MDS & overcoming treatment failure in higher-risk disease

132

iwCAR-T Session III: CAR-T therapy in AML: ongoing challenges and strategies to improve patient outcomes

133

iwCAR-T Session II: CAR-T therapy in ALL: ongoing challenges and future outlooks

134

iwCAR-T Session I: CAR-T therapy in lymphoma and the role of bispecific antibodies

135

iwMyeloma Session III: reaching a cure for multiple myeloma and concepts that need to be addressed

136

The current role of stem cell transplantation in MPNs & how this may change with novel agents

137

iwMyeloma Session II: the tumor microenvironment and mechanisms of resistance to targeted therapies

138

iwMyeloma Session I: genomics of high-risk and smoldering multiple myeloma

139

The important role of transplantation in AML: improving outcomes for patients & the value of pre-transplant MRD

140

Insights into the changing role of chemotherapy in lymphoma

141

Comparing the ICC and WHO classifications for MDS and their impact on clinical practice

142

Managing and treating toxicities associated with CAR-T therapy: CRS, ICANS & infections

143

The growing role of immunotherapy in the treatment of ALL & moving away from stem cell transplantation

144

The current status of CAR-T therapy in CLL and challenges in this space

145

Managing and treating GvHD and other post-transplant complications

146

The role of MRD in multiple myeloma

147

Novel immune therapies in MDS and challenges in this space

148

NHL highlights at ASH 2022: Updates in MCL, the role of transplantation, and novel bispecific antibodies

149

MPN highlights at ASH 2022: Novel agents, combinations & the role of immunotherapy

150

T-cell lymphoma highlights at ASH 2022: Unmet needs, clinical trial updates & future outlooks

151

The importance of CD47 in MDS and other targets of interest

152

CLL highlights at ASH 2022: Clinical trial updates, novel BTK inhibitors & combination therapy

153

Myeloma highlights at ASH 2022: Improving access to CAR-T therapy & future outlooks

154

Highlights in MDS at ASH 2022: Treating lower-risk & higher-risk disease, trial updates, & more

155

iwNHL Session V: Novel therapies in NHL - the role of ADCs

156

iwAL 2022 Session V: Mechanisms of resistance to targeted therapies in AML

157

The importance of genomic testing in CLL and its role in clinical decision-making

158

iwNHL Session IV: T-cell therapies for NHL: CAR-T therapies & third-party EBV T-cells

159

Key updates in CLL: novel treatment strategies, the changing role of chemotherapy, and more

160

iwAL 2022 Session IV: The evolving treatment landscape in ALL and the growing role of immunotherapies

161

iwNHL Session III: Exploring the optimal management of R/R follicular lymphoma in an expanding treatment landscape

162

iwAL 2022 Session III: Novel targets, combinations and treatment strategies in AML

163

Recent updates in CML: treatment strategies, clinical trials, and novel agents

164

iwNHL Session II: Understanding and harnessing the immune microenvironment against lymphoma

165

iwAL 2022 Session II: Novel treatment strategies in ALL

166

The role of the innate immune system in MDS

167

iwAL 2022 Session I: The standard of care in AML in 2022

168

iwNHL 2022 Session I: Advances in the treatment of T-cell lymphoma

169

ISA 2022: meeting highlights and recent updates in amyloidosis

170

Highlights from IMS 2022: managing high-risk & frail patients with myeloma and the prognostic value of MRD

171

Highlights from the 2022 Texas MPN Workshop: early intervention, disease progression & future targets

172

iwMDS 2022: Key highlights

173

Identifying high-risk myeloma and improving treatment strategies in these patients

174

Improving the efficiency of drug approvals in MDS

175

Highlights from the 2022 Texas MPN Workshop: advances in MPN treatment

176

The need for more effective first-line therapies in MDS

177

Myeloma 2022: day two highlights

178

The promise of CAR-T therapy in CLL and challenges in the field

179

Clonal hematopoiesis and pre-MDS states

180

T-cell engagers in multiple myeloma: current challenges and future outlooks

181

High-risk MDS: unmet needs and future treatment approaches

182

The importance of patient-reported outcomes in CAR-T recipients

183

CAR-T therapy in myeloma and lymphoma

184

CAR-T therapy in AML: challenges and future outlooks

185

The current state of CAR-T therapy in lymphoma

186

Myeloma treatment updates from EHA 2022

187

Updates in classification and risk stratification in MDS

188

Myeloma 2022: day one highlights

189

Immune dysregulation and targeting in MDS

190

The future of CAR-T therapy in ALL

191

An insight into novel targets in myeloma and mechanisms of resistance to PIs and IMiDs

192

Key updates in the treatment and management of MPNs

193

Addressing unmet needs and future treatment approaches in AL amyloidosis

194

Myeloma treatment in the UK: updates from Muk Nine b: OPTIMUM & the importance of genomics

195

Updates in lymphoma and CLL treatment in the UK

196

The importance of early intervention and interception in myeloma

197

Impact of the COVID-19 pandemic on the EBMT & projects in the pipeline

198

CAR-T and lymphoma treatment in the UK

199

Harnessing the power of immunotherapy in myeloma and amyloidosis

200

The impact of AI and machine learning algorithms in MDS