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All Episodes

VJHemOnc Podcast — 202 episodes

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Title
1

Advances in gene-based therapies for SCD and thalassemia: access, outcomes & innovation

2

The evolving role of BTK inhibitors in CLL

3

Advances in stem cell transplantation from EBMT 2026: managing GvHD, donor selection & evolving clinical strategies

4

Myeloid Monthly: breaking news & updates from the classification advancement meeting

5

How AI is transforming hematologic oncology

6

MRD in ALL and AML: from prognostic marker to clinical endpoint

7

Nursing in CAR-T & cellular therapy: updates and insights from the EBMT-EHA CAR T-cell Meeting 2026

8

Recent BTK inhibitor trial updates across non-Hodgkin lymphoma subtypes

9

ASH 2025 highlights in AL amyloidosis: risk stratification, bispecific antibodies, CAR-T, & MRD

10

Top ASH 2025 updates in AML: redefining frontline therapy, menin inhibition, venetoclax-based triplets, & emerging immunotherapies

11

Managing and preventing differentiation syndrome in APL

12

Top ASH 2025 NHL updates: novel CAR T-cell therapies, fixed-duration strategies, evolving frontline approaches, & more

13

Top updates in myeloma from ASH 2025: the RedirecTT-1 and MajesTEC-3 trials, dual-targeting CAR-T, trispecific antibodies, and more!

14

Top CLL updates from ASH 2025: novel BTKi monotherapy and combination approaches, BTK degraders, & more

15

Top updates in MDS from ASH 2025: key trial updates and debated topics

16

Sickle cell disease management: navigating the transition from pediatric to adult care, managing VOCs, & more

17

Accelerated- and blast-phase MPNs: diagnosis, management, and current challenges

18

The value and utility of MRD in the management of adults with newly-diagnosed AML

19

Updates from iwHRMM: targeted and immune-related therapies and mechanisms of resistance

20

Advances in immunotherapy for NHL: updates from iwNHL 2025

21

Reviewing recent guideline updates on the risk stratification and treatment of AML

22

The management of CLL in resource-limited settings: guideline development and ongoing projects

23

The multi-disciplinary team in CAR-T therapy: insights from a nurse, a neurologist, and a palliative care specialist

24

Understanding financial and time toxicity in cancer care: advice for community oncologists

25

Listener Q&A special: expert insights on CLL, myeloma, and lymphoma

26

Novel strategies and advances in the management and classification of MDS: insights from iwMDS 2025

27

Advances in Waldenström’s macroglobulinemia: significance of genetic alterations, current treatment strategies, & ongoing trials

28

FLT3-ITD+ AML: recent trial updates, novel approaches, and MRD

29

Extramedullary disease in multiple myeloma: biology, management strategies, & the RedirecTT-1 trial

30

iwMPN 2025 highlights: novel approaches to the upfront management of myelofibrosis, cardiovascular health in MPNs, & more

31

Managing CNS lymphoma: expert insights and updates from ICML 2025

32

iwMDS wrap-up: translating research into practice to optimize patient care

33

Targeting mutant CALR in MPNs with antibodies & cellular therapy: the potential for disease modification

34

Treating elderly or unfit patients with AML: current approach and future directions

35

Key HemOnc updates from ASCO 2025: myeloma, lymphoma, MPNs, & more!

36

CHIP & CCUS: advances in understanding and should we treat these precursor conditions?

37

Diagnosing amyloidosis: identifying early signs, appropriate diagnostic tests, and challenges that remain

38

IPIG 2025 Highlights: challenging situations in PNH, updates from the COMMODORE trials, and more

39

Recent advances in Hodgkin lymphoma treatment: novel regimens, ongoing trials & treating R/R disease

40

Gene therapy in sickle cell disease: patient selection, potential complications, & more

41

Highlights from iwCAR-T 2025: improving the efficacy and safety of CAR T-cells & access in the community

42

Updates to the ESMO CLL clinical practice guidelines and implications for relapsed therapy

43

Highlights from iwMyeloma 2025: trial updates and practical considerations

44

Updates to the ESMO CLL clinical practice guidelines: implications for frontline treatment

45

Highlights from EBMT 2025: preventing and managing GvHD, harnessing AI in transplant, & more

46

Sequencing therapies in R/R NHL: immunotherapy in DLBCL, BTKis in MCL, & more!

47

Novel CAR strategies being explored in lymphoma: allogeneic products, trispecific CARs & new manufacturing platforms

48

Approaches to optimizing induction therapy in AML: FLT3 inhibitors, menin inhibitors, CPX-351, & more!

49

Treating R/R mantle cell lymphoma: the role of BTK inhibitors, combination approaches being explored & overcoming resistance

50

Addressing unmet needs in myeloma: early detection, frail/elderly patients, triple-class exposed disease, & more!

51

CAR T-cell therapy in ALL: trial updates, novel approaches, & real-world outcomes

52

Post-ASH amyloidosis highlights: the ANDROMEDA trial, risk stratification, value of MRD, & more!

53

Post-ASH non-malignant highlights: updates in sickle cell disease, thalassemia, and hemophilia

54

Post-ASH myeloma highlights: key takeaways for community physicians & trials to look out for in 2025

55

Post-ASH AML highlights: novel approaches to frontline therapy, advances with menin inhibitors, & managing FLT3-ITD+ AML

56

Post-ASH MPN highlights: key trial updates in MF, novel approaches being explored in R/R disease, & more!

57

Post-ASH NHL highlights: novel combinations in the frontline setting and advancements with immunotherapy in the R/R setting

58

Post-ASH MDS highlights: managing anemia in LR-MDS and novel approaches to treating HR-MDS

59

Post-ASH CLL highlights: BTK inhibitors & degraders, bispecific antibodies, & more!

60

Advancing treatment for BPDCN: current therapies, a deep dive into tagraxofusp, & emerging novel agents

61

Improving care for patients with SCD: pain management, ongoing projects & unmet needs

62

Understanding BPDCN: dermatology and hematology perspectives on presentation, diagnosis, treatment, & multidisciplinary care

63

Managing complications associated with WM: Bing-Neel syndrome, acquired von Willebrand disease, & more!

64

CAR-T therapies and bispecific antibodies in the treatment of high-risk multiple myeloma: updates from iwHRMM 2024

65

The treatment landscape and challenges in rare diseases: BPDCN, CMML, MPN-AP/BP, and VEXAS

66

Exploring the role of BTK inhibitors in mantle cell lymphoma: sequencing & managing adverse events

67

An update on menin inhibition in AML from iwAL 2024: current data, mechanisms of resistance, & more!

68

CAR T-cells and bispecific antibodies in the treatment of NHL: updates from iwNHL 2024

69

Prolonging remission in AML: current approaches & future outlooks

70

A focus on the use of artificial intelligence to personalize blood cancer care

71

A focus on pediatric leukemias: trials, treatments, & challenges

72

A focus on the psychosocial impacts of living with blood cancer

73

Global perspectives on blood cancers: addressing disparities in awareness, diagnosis, and treatment

74

Insights into PV and ET: treating the AYA population, defining goals when treating patients, & more

75

Hemophilia updates from ISTH 2024: ongoing clinical trials, emerging gene therapies & remaining challenges

76

Inflammation and immune interventions in MDS: targeting STAT, IRAK4, & more

77

Updates in the treatment of SCD and thalassemia from EHA 2024: key trial updates, challenges with gene therapies & unmet needs

78

Unmet treatment needs in MF: managing prefibrotic disease & thrombocytopenia, novel agents & endpoints for clinical trials

79

The role of BTK inhibitors in MCL, ongoing trials & future outlooks: updates from EHA 2024

80

Novel developments in lower-risk MDS & important practical considerations when treating patients

81

Updates on the use of BCMA-targeting bispecific antibodies in R/R multiple myeloma: insights from EHA & ASCO 2024

82

Updates in the treatment of CLL from EHA 2024: BTK and BCL2 inhibitor combinations, BTK degraders, and more

83

Highlights from ISA 2024: the importance of early diagnosis in AL amyloidosis, trials in progress & patient selection for SCT

84

Treating LR-MDS beyond ESA failure: currently approved agents, novel approaches & future outlooks

85

BPDCN treatment and management: CD123-targeting agents, CNS involvement & approaching pediatric/AYA patients

86

The future of CAR-T therapy in lymphoma, addressing the risk of secondary malignancy & the optimal sequencing of these agents with bispecific antibodies

87

iwMyeloma 2024 Session I: approaching bone disease, clinical trial updates & the value of MRD as an endpoint in trials

88

Managing anemia in MF, key emerging trials in the UK, and approaching young patients with MPNs

89

Highlights from EBMT 2024: treating & managing GvHD & understanding the role of the gut microbiome

90

The importance of cardio-oncology: awareness around the ESC 2022 guidelines & the value of building MDTs

91

Exploring the possibility of early interception in smoldering myeloma: novel agents, challenges & advances in risk stratification

92

CHIP & CCUS: knowledge gaps, ongoing trials & recommendations for approaching patients with myeloid precursors

93

Monoclonal B-cell lymphocytosis: classification, biology and exploring the possibility of early interception

94

The impact of CAR-T therapy on the myeloma treatment landscape, patient selection for CAR-T & the evolving role of autoSCT

95

Diagnosing amyloidosis, currently available therapies & the importance of cardio-oncology

96

Addressing the importance of lymphodepletion, factors contributing to ICAHT & the cost effectiveness of CAR-T therapy

97

Updates with the use of CAR-T therapy in ALL: ongoing challenges, strategies to overcome resistance & future outlooks

98

Targeted therapy in AML: the growing role of menin inhibitors & clinical trials exploring these agents

99

Updates in lower- and higher-risk MDS: challenges, novel agents & key clinical trials at ASH 2023

100

Key updates in thalassemia at ASH 2023: gene therapies, ongoing trials & the value of precision medicine

101

Updates, challenges and novel agents being explored in BPDCN

102

Unanswered questions regarding the sequencing of BCMA therapies, the prognostic value of CTCs & the growing role of quadruplets

103

Key updates in sickle cell disease at ASH 2023: disease biology, ongoing trials & the growing role of gene therapy

104

ASH 2023 highlights: updates in the diagnosis and treatment of amyloidosis

105

MPN highlights at ASH 2023: novel agents & ongoing clinical trials in ET, PV and MF

106

iwNHL 2023 Session V: Expanding the CAR platform in NHL

107

iwCLL 2023: The role of continuous BTKis, approaching Richter’s transformation & addressing the underrepresentation of elderly patients in trials

108

iwNHL 2023 Session IV: Novel therapies in NHL: BTK inhibitors, BTK degraders, and bispecific antibodies

109

Unmet needs in AL amyloidosis, novel treatment strategies being explored, and the role of CHIP

110

iwNHL 2023 Session III: Recent updates with the use of antibody-drug conjugates in NHL

111

MPN diagnosis & treatment: novel agents in PV, clinical guidance for the use of JAK inhibitors & the growing role of combination approaches

112

iwNHL 2023 Session II: The evolving treatment landscape in mantle cell lymphoma

113

iwNHL 2023 Session I: Updates on the biology and treatment of T-cell lymphoma

114

iwAL 2023 Session IV: transplantation and immunotherapies in AML: improving patient outcomes

115

Classifying frailty and approaching elderly patients with lymphoma

116

Updates on the diagnosis, risk stratification and treatment of lower-risk MDS

117

iwAL 2023 Session III: The relevance of TP53 mutation in AML

118

iwAL 2023 Session II: Novel treatments in AML: FLT3 inhibitors, combinations, and more

119

iwAL 2023 Session I: Clonal hematopoiesis in AML, early detection and potential therapeutics

120

Applications of MRD in multiple myeloma: using MRD to guide treatment decisions

121

Exploring and comparing the curative potential of CAR-T therapy & bispecific antibodies in R/R DLBCL

122

Pre-MDS states: improving prognosis, novel therapeutic approaches, and challenges with distinguishing these conditions

123

Accelerated-phase MPNs: mutational landscape, challenges, and novel treatment strategies being explored

124

Determining the optimal sequencing of bispecifics and CAR-T cells in multiple myeloma

125

Overcoming barriers to CAR-T therapy: improving access and cost

126

The importance of addressing quality of life and improving symptom management in MPNs

127

Updates in the treatment and management of amyloidosis and the importance of the multidisciplinary team

128

Hemophilia: the current standard of care and the value of novel gene therapies

129

CLL highlights at EHA 2023: latest advances with the use of BTK inhibitors

130

Myeloma highlights at EHA 2023: CARTITUDE-4 & CARTITUDE-1 updates & the use of MRD in clinical practice

131

Lymphoma highlights at EHA 2023: sequencing bispecifics & CAR-T cells, bridging therapy & toxicity management

132

iwCAR-T Session IV: CAR-T therapy in CLL: challenges, combination approaches and ongoing trials

133

MDS 2023 highlights: managing anemia in lower-risk MDS & overcoming treatment failure in higher-risk disease

134

iwCAR-T Session III: CAR-T therapy in AML: ongoing challenges and strategies to improve patient outcomes

135

iwCAR-T Session II: CAR-T therapy in ALL: ongoing challenges and future outlooks

136

iwCAR-T Session I: CAR-T therapy in lymphoma and the role of bispecific antibodies

137

iwMyeloma Session III: reaching a cure for multiple myeloma and concepts that need to be addressed

138

The current role of stem cell transplantation in MPNs & how this may change with novel agents

139

iwMyeloma Session II: the tumor microenvironment and mechanisms of resistance to targeted therapies

140

iwMyeloma Session I: genomics of high-risk and smoldering multiple myeloma

141

The important role of transplantation in AML: improving outcomes for patients & the value of pre-transplant MRD

142

Insights into the changing role of chemotherapy in lymphoma

143

Comparing the ICC and WHO classifications for MDS and their impact on clinical practice

144

Managing and treating toxicities associated with CAR-T therapy: CRS, ICANS & infections

145

The growing role of immunotherapy in the treatment of ALL & moving away from stem cell transplantation

146

The current status of CAR-T therapy in CLL and challenges in this space

147

Managing and treating GvHD and other post-transplant complications

148

The role of MRD in multiple myeloma

149

Novel immune therapies in MDS and challenges in this space

150

NHL highlights at ASH 2022: Updates in MCL, the role of transplantation, and novel bispecific antibodies

151

MPN highlights at ASH 2022: Novel agents, combinations & the role of immunotherapy

152

T-cell lymphoma highlights at ASH 2022: Unmet needs, clinical trial updates & future outlooks

153

The importance of CD47 in MDS and other targets of interest

154

CLL highlights at ASH 2022: Clinical trial updates, novel BTK inhibitors & combination therapy

155

Myeloma highlights at ASH 2022: Improving access to CAR-T therapy & future outlooks

156

Highlights in MDS at ASH 2022: Treating lower-risk & higher-risk disease, trial updates, & more

157

iwNHL Session V: Novel therapies in NHL - the role of ADCs

158

iwAL 2022 Session V: Mechanisms of resistance to targeted therapies in AML

159

The importance of genomic testing in CLL and its role in clinical decision-making

160

iwNHL Session IV: T-cell therapies for NHL: CAR-T therapies & third-party EBV T-cells

161

Key updates in CLL: novel treatment strategies, the changing role of chemotherapy, and more

162

iwAL 2022 Session IV: The evolving treatment landscape in ALL and the growing role of immunotherapies

163

iwNHL Session III: Exploring the optimal management of R/R follicular lymphoma in an expanding treatment landscape

164

iwAL 2022 Session III: Novel targets, combinations and treatment strategies in AML

165

Recent updates in CML: treatment strategies, clinical trials, and novel agents

166

iwNHL Session II: Understanding and harnessing the immune microenvironment against lymphoma

167

iwAL 2022 Session II: Novel treatment strategies in ALL

168

The role of the innate immune system in MDS

169

iwAL 2022 Session I: The standard of care in AML in 2022

170

iwNHL 2022 Session I: Advances in the treatment of T-cell lymphoma

171

ISA 2022: meeting highlights and recent updates in amyloidosis

172

Highlights from IMS 2022: managing high-risk & frail patients with myeloma and the prognostic value of MRD

173

Highlights from the 2022 Texas MPN Workshop: early intervention, disease progression & future targets

174

iwMDS 2022: Key highlights

175

Identifying high-risk myeloma and improving treatment strategies in these patients

176

Improving the efficiency of drug approvals in MDS

177

Highlights from the 2022 Texas MPN Workshop: advances in MPN treatment

178

The need for more effective first-line therapies in MDS

179

Myeloma 2022: day two highlights

180

The promise of CAR-T therapy in CLL and challenges in the field

181

Clonal hematopoiesis and pre-MDS states

182

T-cell engagers in multiple myeloma: current challenges and future outlooks

183

High-risk MDS: unmet needs and future treatment approaches

184

The importance of patient-reported outcomes in CAR-T recipients

185

CAR-T therapy in myeloma and lymphoma

186

CAR-T therapy in AML: challenges and future outlooks

187

The current state of CAR-T therapy in lymphoma

188

Myeloma treatment updates from EHA 2022

189

Updates in classification and risk stratification in MDS

190

Myeloma 2022: day one highlights

191

Immune dysregulation and targeting in MDS

192

The future of CAR-T therapy in ALL

193

An insight into novel targets in myeloma and mechanisms of resistance to PIs and IMiDs

194

Key updates in the treatment and management of MPNs

195

Addressing unmet needs and future treatment approaches in AL amyloidosis

196

Myeloma treatment in the UK: updates from Muk Nine b: OPTIMUM & the importance of genomics

197

Updates in lymphoma and CLL treatment in the UK

198

The importance of early intervention and interception in myeloma

199

Impact of the COVID-19 pandemic on the EBMT & projects in the pipeline

200

CAR-T and lymphoma treatment in the UK

201

Harnessing the power of immunotherapy in myeloma and amyloidosis

202

The impact of AI and machine learning algorithms in MDS