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All Episodes

VJHemOnc Podcast — 217 episodes

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Title
1

Using BTK inhibitors in lymphoma: practical considerations for community physicians

2

AAV gene therapy in hemophilia: progress, challenges and what comes next

3

Clinical considerations in MCL management: frailty assessment, the multidisciplinary team & managing the use of BTKis

4

Sequencing therapies in multiple myeloma: navigating an expanding treatment landscape

5

The evolving treatment landscape in ALL: the growing role of immunotherapy and reduced reliance on chemotherapy

6

Precision medicine in MDS: tailoring treatment through molecular profiling

7

The current and future role of BTK inhibitors across non-Hodgkin lymphoma subtypes

8

The diagnosis and management of hematologic malignancies during pregnancy

9

Hodgkin lymphoma in 2026: frontline strategies, ctDNA, and treatment after relapse

10

Sequencing BTK inhibitor therapy in CLL: treatment considerations and emerging strategies

11

Precision medicine in AML: from targeted therapy to transplantation

12

MPNs in focus: disease progression, risk assessment, and emerging treatments

13

The evolving role of cellular therapies and T-cell engagers in lymphoma

14

Multiple myeloma in 2026: MRD, BCMA therapies, CAR-T, and the path to cure

15

Dual-targeting CAR T-cell therapies in LBCL: efficacy, safety, and bridging therapy

16

Advances in gene-based therapies for SCD and thalassemia: access, outcomes & innovation

17

The evolving role of BTK inhibitors in CLL

18

Advances in stem cell transplantation from EBMT 2026: managing GvHD, donor selection & evolving clinical strategies

19

Myeloid Monthly: breaking news & updates from the classification advancement meeting

20

How AI is transforming hematologic oncology

21

MRD in ALL and AML: from prognostic marker to clinical endpoint

22

Nursing in CAR-T & cellular therapy: updates and insights from the EBMT-EHA CAR T-cell Meeting 2026

23

Recent BTK inhibitor trial updates across non-Hodgkin lymphoma subtypes

24

ASH 2025 highlights in AL amyloidosis: risk stratification, bispecific antibodies, CAR-T, & MRD

25

Top ASH 2025 updates in AML: redefining frontline therapy, menin inhibition, venetoclax-based triplets, & emerging immunotherapies

26

Managing and preventing differentiation syndrome in APL

27

Top ASH 2025 NHL updates: novel CAR T-cell therapies, fixed-duration strategies, evolving frontline approaches, & more

28

Top updates in myeloma from ASH 2025: the RedirecTT-1 and MajesTEC-3 trials, dual-targeting CAR-T, trispecific antibodies, and more!

29

Top CLL updates from ASH 2025: novel BTKi monotherapy and combination approaches, BTK degraders, & more

30

Top updates in MDS from ASH 2025: key trial updates and debated topics

31

Sickle cell disease management: navigating the transition from pediatric to adult care, managing VOCs, & more

32

Accelerated- and blast-phase MPNs: diagnosis, management, and current challenges

33

The value and utility of MRD in the management of adults with newly-diagnosed AML

34

Updates from iwHRMM: targeted and immune-related therapies and mechanisms of resistance

35

Advances in immunotherapy for NHL: updates from iwNHL 2025

36

Reviewing recent guideline updates on the risk stratification and treatment of AML

37

The management of CLL in resource-limited settings: guideline development and ongoing projects

38

The multi-disciplinary team in CAR-T therapy: insights from a nurse, a neurologist, and a palliative care specialist

39

Understanding financial and time toxicity in cancer care: advice for community oncologists

40

Listener Q&A special: expert insights on CLL, myeloma, and lymphoma

41

Novel strategies and advances in the management and classification of MDS: insights from iwMDS 2025

42

Advances in Waldenström’s macroglobulinemia: significance of genetic alterations, current treatment strategies, & ongoing trials

43

FLT3-ITD+ AML: recent trial updates, novel approaches, and MRD

44

Extramedullary disease in multiple myeloma: biology, management strategies, & the RedirecTT-1 trial

45

iwMPN 2025 highlights: novel approaches to the upfront management of myelofibrosis, cardiovascular health in MPNs, & more

46

Managing CNS lymphoma: expert insights and updates from ICML 2025

47

iwMDS wrap-up: translating research into practice to optimize patient care

48

Targeting mutant CALR in MPNs with antibodies & cellular therapy: the potential for disease modification

49

Treating elderly or unfit patients with AML: current approach and future directions

50

Key HemOnc updates from ASCO 2025: myeloma, lymphoma, MPNs, & more!

51

CHIP & CCUS: advances in understanding and should we treat these precursor conditions?

52

Diagnosing amyloidosis: identifying early signs, appropriate diagnostic tests, and challenges that remain

53

IPIG 2025 Highlights: challenging situations in PNH, updates from the COMMODORE trials, and more

54

Recent advances in Hodgkin lymphoma treatment: novel regimens, ongoing trials & treating R/R disease

55

Gene therapy in sickle cell disease: patient selection, potential complications, & more

56

Highlights from iwCAR-T 2025: improving the efficacy and safety of CAR T-cells & access in the community

57

Updates to the ESMO CLL clinical practice guidelines and implications for relapsed therapy

58

Highlights from iwMyeloma 2025: trial updates and practical considerations

59

Updates to the ESMO CLL clinical practice guidelines: implications for frontline treatment

60

Highlights from EBMT 2025: preventing and managing GvHD, harnessing AI in transplant, & more

61

Sequencing therapies in R/R NHL: immunotherapy in DLBCL, BTKis in MCL, & more!

62

Novel CAR strategies being explored in lymphoma: allogeneic products, trispecific CARs & new manufacturing platforms

63

Approaches to optimizing induction therapy in AML: FLT3 inhibitors, menin inhibitors, CPX-351, & more!

64

Treating R/R mantle cell lymphoma: the role of BTK inhibitors, combination approaches being explored & overcoming resistance

65

Addressing unmet needs in myeloma: early detection, frail/elderly patients, triple-class exposed disease, & more!

66

CAR T-cell therapy in ALL: trial updates, novel approaches, & real-world outcomes

67

Post-ASH amyloidosis highlights: the ANDROMEDA trial, risk stratification, value of MRD, & more!

68

Post-ASH non-malignant highlights: updates in sickle cell disease, thalassemia, and hemophilia

69

Post-ASH myeloma highlights: key takeaways for community physicians & trials to look out for in 2025

70

Post-ASH AML highlights: novel approaches to frontline therapy, advances with menin inhibitors, & managing FLT3-ITD+ AML

71

Post-ASH MPN highlights: key trial updates in MF, novel approaches being explored in R/R disease, & more!

72

Post-ASH NHL highlights: novel combinations in the frontline setting and advancements with immunotherapy in the R/R setting

73

Post-ASH MDS highlights: managing anemia in LR-MDS and novel approaches to treating HR-MDS

74

Post-ASH CLL highlights: BTK inhibitors & degraders, bispecific antibodies, & more!

75

Advancing treatment for BPDCN: current therapies, a deep dive into tagraxofusp, & emerging novel agents

76

Improving care for patients with SCD: pain management, ongoing projects & unmet needs

77

Understanding BPDCN: dermatology and hematology perspectives on presentation, diagnosis, treatment, & multidisciplinary care

78

Managing complications associated with WM: Bing-Neel syndrome, acquired von Willebrand disease, & more!

79

CAR-T therapies and bispecific antibodies in the treatment of high-risk multiple myeloma: updates from iwHRMM 2024

80

The treatment landscape and challenges in rare diseases: BPDCN, CMML, MPN-AP/BP, and VEXAS

81

Exploring the role of BTK inhibitors in mantle cell lymphoma: sequencing & managing adverse events

82

An update on menin inhibition in AML from iwAL 2024: current data, mechanisms of resistance, & more!

83

CAR T-cells and bispecific antibodies in the treatment of NHL: updates from iwNHL 2024

84

Prolonging remission in AML: current approaches & future outlooks

85

A focus on the use of artificial intelligence to personalize blood cancer care

86

A focus on pediatric leukemias: trials, treatments, & challenges

87

A focus on the psychosocial impacts of living with blood cancer

88

Global perspectives on blood cancers: addressing disparities in awareness, diagnosis, and treatment

89

Insights into PV and ET: treating the AYA population, defining goals when treating patients, & more

90

Hemophilia updates from ISTH 2024: ongoing clinical trials, emerging gene therapies & remaining challenges

91

Inflammation and immune interventions in MDS: targeting STAT, IRAK4, & more

92

Updates in the treatment of SCD and thalassemia from EHA 2024: key trial updates, challenges with gene therapies & unmet needs

93

Unmet treatment needs in MF: managing prefibrotic disease & thrombocytopenia, novel agents & endpoints for clinical trials

94

The role of BTK inhibitors in MCL, ongoing trials & future outlooks: updates from EHA 2024

95

Novel developments in lower-risk MDS & important practical considerations when treating patients

96

Updates on the use of BCMA-targeting bispecific antibodies in R/R multiple myeloma: insights from EHA & ASCO 2024

97

Updates in the treatment of CLL from EHA 2024: BTK and BCL2 inhibitor combinations, BTK degraders, and more

98

Highlights from ISA 2024: the importance of early diagnosis in AL amyloidosis, trials in progress & patient selection for SCT

99

Treating LR-MDS beyond ESA failure: currently approved agents, novel approaches & future outlooks

100

BPDCN treatment and management: CD123-targeting agents, CNS involvement & approaching pediatric/AYA patients

101

The future of CAR-T therapy in lymphoma, addressing the risk of secondary malignancy & the optimal sequencing of these agents with bispecific antibodies

102

iwMyeloma 2024 Session I: approaching bone disease, clinical trial updates & the value of MRD as an endpoint in trials

103

Managing anemia in MF, key emerging trials in the UK, and approaching young patients with MPNs

104

Highlights from EBMT 2024: treating & managing GvHD & understanding the role of the gut microbiome

105

The importance of cardio-oncology: awareness around the ESC 2022 guidelines & the value of building MDTs

106

Exploring the possibility of early interception in smoldering myeloma: novel agents, challenges & advances in risk stratification

107

CHIP & CCUS: knowledge gaps, ongoing trials & recommendations for approaching patients with myeloid precursors

108

Monoclonal B-cell lymphocytosis: classification, biology and exploring the possibility of early interception

109

The impact of CAR-T therapy on the myeloma treatment landscape, patient selection for CAR-T & the evolving role of autoSCT

110

Diagnosing amyloidosis, currently available therapies & the importance of cardio-oncology

111

Addressing the importance of lymphodepletion, factors contributing to ICAHT & the cost effectiveness of CAR-T therapy

112

Updates with the use of CAR-T therapy in ALL: ongoing challenges, strategies to overcome resistance & future outlooks

113

Targeted therapy in AML: the growing role of menin inhibitors & clinical trials exploring these agents

114

Updates in lower- and higher-risk MDS: challenges, novel agents & key clinical trials at ASH 2023

115

Key updates in thalassemia at ASH 2023: gene therapies, ongoing trials & the value of precision medicine

116

Updates, challenges and novel agents being explored in BPDCN

117

Unanswered questions regarding the sequencing of BCMA therapies, the prognostic value of CTCs & the growing role of quadruplets

118

Key updates in sickle cell disease at ASH 2023: disease biology, ongoing trials & the growing role of gene therapy

119

ASH 2023 highlights: updates in the diagnosis and treatment of amyloidosis

120

MPN highlights at ASH 2023: novel agents & ongoing clinical trials in ET, PV and MF

121

iwNHL 2023 Session V: Expanding the CAR platform in NHL

122

iwCLL 2023: The role of continuous BTKis, approaching Richter’s transformation & addressing the underrepresentation of elderly patients in trials

123

iwNHL 2023 Session IV: Novel therapies in NHL: BTK inhibitors, BTK degraders, and bispecific antibodies

124

Unmet needs in AL amyloidosis, novel treatment strategies being explored, and the role of CHIP

125

iwNHL 2023 Session III: Recent updates with the use of antibody-drug conjugates in NHL

126

MPN diagnosis & treatment: novel agents in PV, clinical guidance for the use of JAK inhibitors & the growing role of combination approaches

127

iwNHL 2023 Session II: The evolving treatment landscape in mantle cell lymphoma

128

iwNHL 2023 Session I: Updates on the biology and treatment of T-cell lymphoma

129

iwAL 2023 Session IV: transplantation and immunotherapies in AML: improving patient outcomes

130

Classifying frailty and approaching elderly patients with lymphoma

131

Updates on the diagnosis, risk stratification and treatment of lower-risk MDS

132

iwAL 2023 Session III: The relevance of TP53 mutation in AML

133

iwAL 2023 Session II: Novel treatments in AML: FLT3 inhibitors, combinations, and more

134

iwAL 2023 Session I: Clonal hematopoiesis in AML, early detection and potential therapeutics

135

Applications of MRD in multiple myeloma: using MRD to guide treatment decisions

136

Exploring and comparing the curative potential of CAR-T therapy & bispecific antibodies in R/R DLBCL

137

Pre-MDS states: improving prognosis, novel therapeutic approaches, and challenges with distinguishing these conditions

138

Accelerated-phase MPNs: mutational landscape, challenges, and novel treatment strategies being explored

139

Determining the optimal sequencing of bispecifics and CAR-T cells in multiple myeloma

140

Overcoming barriers to CAR-T therapy: improving access and cost

141

The importance of addressing quality of life and improving symptom management in MPNs

142

Updates in the treatment and management of amyloidosis and the importance of the multidisciplinary team

143

Hemophilia: the current standard of care and the value of novel gene therapies

144

CLL highlights at EHA 2023: latest advances with the use of BTK inhibitors

145

Myeloma highlights at EHA 2023: CARTITUDE-4 & CARTITUDE-1 updates & the use of MRD in clinical practice

146

Lymphoma highlights at EHA 2023: sequencing bispecifics & CAR-T cells, bridging therapy & toxicity management

147

iwCAR-T Session IV: CAR-T therapy in CLL: challenges, combination approaches and ongoing trials

148

MDS 2023 highlights: managing anemia in lower-risk MDS & overcoming treatment failure in higher-risk disease

149

iwCAR-T Session III: CAR-T therapy in AML: ongoing challenges and strategies to improve patient outcomes

150

iwCAR-T Session II: CAR-T therapy in ALL: ongoing challenges and future outlooks

151

iwCAR-T Session I: CAR-T therapy in lymphoma and the role of bispecific antibodies

152

iwMyeloma Session III: reaching a cure for multiple myeloma and concepts that need to be addressed

153

The current role of stem cell transplantation in MPNs & how this may change with novel agents

154

iwMyeloma Session II: the tumor microenvironment and mechanisms of resistance to targeted therapies

155

iwMyeloma Session I: genomics of high-risk and smoldering multiple myeloma

156

The important role of transplantation in AML: improving outcomes for patients & the value of pre-transplant MRD

157

Insights into the changing role of chemotherapy in lymphoma

158

Comparing the ICC and WHO classifications for MDS and their impact on clinical practice

159

Managing and treating toxicities associated with CAR-T therapy: CRS, ICANS & infections

160

The growing role of immunotherapy in the treatment of ALL & moving away from stem cell transplantation

161

The current status of CAR-T therapy in CLL and challenges in this space

162

Managing and treating GvHD and other post-transplant complications

163

The role of MRD in multiple myeloma

164

Novel immune therapies in MDS and challenges in this space

165

NHL highlights at ASH 2022: Updates in MCL, the role of transplantation, and novel bispecific antibodies

166

MPN highlights at ASH 2022: Novel agents, combinations & the role of immunotherapy

167

T-cell lymphoma highlights at ASH 2022: Unmet needs, clinical trial updates & future outlooks

168

The importance of CD47 in MDS and other targets of interest

169

CLL highlights at ASH 2022: Clinical trial updates, novel BTK inhibitors & combination therapy

170

Myeloma highlights at ASH 2022: Improving access to CAR-T therapy & future outlooks

171

Highlights in MDS at ASH 2022: Treating lower-risk & higher-risk disease, trial updates, & more

172

iwNHL Session V: Novel therapies in NHL - the role of ADCs

173

iwAL 2022 Session V: Mechanisms of resistance to targeted therapies in AML

174

The importance of genomic testing in CLL and its role in clinical decision-making

175

iwNHL Session IV: T-cell therapies for NHL: CAR-T therapies & third-party EBV T-cells

176

Key updates in CLL: novel treatment strategies, the changing role of chemotherapy, and more

177

iwAL 2022 Session IV: The evolving treatment landscape in ALL and the growing role of immunotherapies

178

iwNHL Session III: Exploring the optimal management of R/R follicular lymphoma in an expanding treatment landscape

179

iwAL 2022 Session III: Novel targets, combinations and treatment strategies in AML

180

Recent updates in CML: treatment strategies, clinical trials, and novel agents

181

iwNHL Session II: Understanding and harnessing the immune microenvironment against lymphoma

182

iwAL 2022 Session II: Novel treatment strategies in ALL

183

The role of the innate immune system in MDS

184

iwAL 2022 Session I: The standard of care in AML in 2022

185

iwNHL 2022 Session I: Advances in the treatment of T-cell lymphoma

186

ISA 2022: meeting highlights and recent updates in amyloidosis

187

Highlights from IMS 2022: managing high-risk & frail patients with myeloma and the prognostic value of MRD

188

Highlights from the 2022 Texas MPN Workshop: early intervention, disease progression & future targets

189

iwMDS 2022: Key highlights

190

Identifying high-risk myeloma and improving treatment strategies in these patients

191

Improving the efficiency of drug approvals in MDS

192

Highlights from the 2022 Texas MPN Workshop: advances in MPN treatment

193

The need for more effective first-line therapies in MDS

194

Myeloma 2022: day two highlights

195

The promise of CAR-T therapy in CLL and challenges in the field

196

Clonal hematopoiesis and pre-MDS states

197

T-cell engagers in multiple myeloma: current challenges and future outlooks

198

High-risk MDS: unmet needs and future treatment approaches

199

The importance of patient-reported outcomes in CAR-T recipients

200

CAR-T therapy in myeloma and lymphoma

201

CAR-T therapy in AML: challenges and future outlooks

202

The current state of CAR-T therapy in lymphoma

203

Myeloma treatment updates from EHA 2022

204

Updates in classification and risk stratification in MDS

205

Myeloma 2022: day one highlights

206

Immune dysregulation and targeting in MDS

207

The future of CAR-T therapy in ALL

208

An insight into novel targets in myeloma and mechanisms of resistance to PIs and IMiDs

209

Key updates in the treatment and management of MPNs

210

Addressing unmet needs and future treatment approaches in AL amyloidosis

211

Myeloma treatment in the UK: updates from Muk Nine b: OPTIMUM & the importance of genomics

212

Updates in lymphoma and CLL treatment in the UK

213

The importance of early intervention and interception in myeloma

214

Impact of the COVID-19 pandemic on the EBMT & projects in the pipeline

215

CAR-T and lymphoma treatment in the UK

216

Harnessing the power of immunotherapy in myeloma and amyloidosis

217

The impact of AI and machine learning algorithms in MDS