PODCAST · health
The Energy Blueprint Podcast
by Ari Whitten
The go-to source for the latest cutting-edge science on overcoming fatigue and increasing your energy. The Energy Blueprint podcast brings together the world's leading researchers, doctors, and nutrition and lifestyle experts on the subject of fatigue and energy to help you get your energy back.
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Fixing Midlife Hormonal Symptoms Using Food with Dr. Alan Christianson
In this episode, I speak with Dr. Alan Christianson, a board-certified naturopathic endocrinologist and the founding president of the Endocrine Association of Naturopathic Physicians and the American College of Thyroidology. We'll discuss his new book, the Hormone Healing Cookbook, and specific foods for resolving pesky symptoms driven by hormonal changes in midlife.
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Caroline Alan (The Mineral Geek): How Fulvic and Humic Substances Power Your Cells
In this episode, I'm speaking with Caroline Alan, the self-proclaimed "Mineral Geek." She shares her history of serious health problems, including gut inflammation, periodontal disease with bone loss in her teeth, recurring sinus infections, brain fog so bad she left her corporate career, and lifelong insomnia. But her health completely transformed thanks to a chance suggestion from her business partner to try liquid minerals. Caroline is now passionate about sharing the connections she's found between mineral depletion, replenishment, and cellular function. She's also a soon-to-be published author; her book, The Mineral Reset: The Essential Guide to Replenishing Your Body and Restoring Your Health, will be available at the end of April.
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The New Science of Metabolism: How to Burn Fat Without Deprivation
Most people think body fat is the problem. If you gain weight, the goal is simple: eat less, burn more, and try to get rid of it. But what if that way of thinking is fundamentally flawed? Today, I'm joined by Dr. William Li, a world-renowned physician and scientist who has led the development of more than 30 new medical treatments that impact care for over 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. Dr. Li has spent decades studying the biology of metabolism, fat, and disease. In his view, body fat itself is not the enemy. In fact, it plays a critical role in your health. The real problem begins when fat becomes excessive, dysfunctional, and inflammatory, disrupting the systems that regulate metabolism and energy balance. This shift in perspective changes everything.
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Natural Ways to Beat High Blood Pressure with Dr. Christopher Pickard
In this episode, I'm speaking with Dr. Christopher Pickard, a hypertension expert with decades of expertise studying nutrition and lifestyle on how to get your blood pressure back down into the healthy range. In this podcast, Dr. Pickard and I discuss: The link between high blood pressure and the risk of dying from COVID-19…and how Dr. Pickard is using this knowledge to help his patients What high blood pressure is actually trying to tell you—it's not a disease; it's a warning sign of something more 3 unexpected causes for hypertension and the problem with simply "fixing it" with a pill 7 practical ways you can start addressing high blood pressure NOW Why breathing through your nose (versus your mouth) might be the missing piece to solving some people's hypertension One amazingly simple step you can take to increase nitric oxide (and decrease blood pressure!) Learn the best fruit to eat to support healthy blood pressure levels!
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Plasmapheresis for Longevity and Chronic Disease with Dr. Eric Gordon
Most people think of chronic illness as something caused by a specific trigger…an infection, a toxin, or even an autoimmune reaction. And the solution is to find and eliminate that one thing. But what if that's not how it actually works? Today, I'm excited to have Dr. Eric Gordon back on the podcast. He's built a reputation for doing what most doctors won't, which is looking beyond the diagnosis to find what's actually driving a patient's illness and figuring out the right order to address it. His clinical work spans Lyme disease, ME/CFS, autoimmune conditions, and mitochondrial dysfunction, and many other forms of dysfunction, often all at once in the same patient. In 2016, he co-authored a landmark study with Dr. Robert Naviaux, also a former guest on this podcast and a bit of a personal hero of mine, someone who has done some of the most important work in medicine of the last century, with his work on the cell danger response. In Dr. Gordon's view, chronic illness happens when the body's normal healing cycle gets interrupted and stuck in a persistent inflammatory state. From that perspective, the problem isn't just the original trigger. It's the state your body has shifted into. And if that's true, it changes how you approach treatment. That shift in thinking opens the door to very different kinds of interventions. These approaches focus on changing the broader biological environment rather than chasing a single cause. In this episode, Dr. Gordon and I discuss a therapy that filters and replaces part of your blood plasma and may help remove inflammatory factors circulating in the blood that keep the body stuck. In this podcast, Dr. Eric Gordon and I discuss: Why chronic illness often reflects a body stuck in the wrong healing state; compensations the body makes for stressors are designed to be short-term, not chronic What happens when the body's normal repair cycle gets interrupted Why the body's response, not the original trigger, can keep people sick The surprising role of "old information" in ongoing dysfunction Why trying to fix one problem at a time often falls short in people with overlapping conditions Dr. Gordon explains why treating the body as a machine will never work - biological reductionism is the fundamental error How a fascinating intervention called plasmapheresis works to filter and replace blood plasma and lower inflammatory load Why plasmapheresis is gaining attention in chronic illness and longevity Dr. Gordon's belief that medicine is faulty because it's hooked on specificity, that the more we can do exactly what we want, the better…but this approach is lacking because we don't know exactly how our bodies work
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The Neuroscience of Fixing Anxiety Fast (Do This Every Day) with Neuroscientist Mark Waldman
In this episode of The Energy Blueprint, I'm speaking with neuroscientist and bestselling author Mark Waldman. Mark has been on the podcast multiple times, but I find his information so interesting that I'm excited to have him back today. Mark is now working in a new field called network neuroscience. During our conversation, he explains the framework of this field and shares some very practical but very effective steps to reduce mind-wandering and improve psychotherapy outcomes.
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Metabolic Health, Food Quality, Fasting, and More with Dr. Ritamarie Loscalzo
A 2018 study found that 88% of the population is metabolically unwell. But more recent studies estimate the number is closer to 92%! My guest today is Dr. Ritamarie Loscalzo, founder of the Institute of Nutritional Endocrinology. She has 30+ years of clinical experience and sees imbalanced blood sugar and disordered insulin regulation as the underlying cause of so many people's problems. Her bottom line is that to get fuel into your mitochondria, good insulin and blood sugar control is a non-negotiable. Most people think of insulin resistance as the diagnosis you get from your doctor, but by that point, there's already been retinopathies (damage to retinas), neuropathies (damage to peripheral nerves), damage to kidneys, and damage to blood vessel linings. Dr. Loscalzo focuses on "pre-insulin resistance," catching the breakdown decades before diagnosis, when you can actually prevent it. This episode was initially released in November 2022
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Dr. Amie Hornaman on The Root Causes of Hashimoto's, Testosterone, & Hormone Replacement Therapy and more
Today's podcast guest is Dr. Amie Hornaman, most well-known as The Thyroid Fixer. She was a figure competitor and powerlifter who gained 25 pounds eating chicken, broccoli, and asparagus while hitting the gym twice a day. Biologically, it didn't make sense. It took seven doctors before she got diagnosed with Hashimoto's, and the sixth one made her cry in her car, praying that something was wrong because, as she told me, "if something was wrong, we could fix it." The seventh doctor gave her Synthroid, and after five months, there was zero change. Not one pound lost, no energy gained, hair still falling out. In this episode, she explains that nearly all diagnoses of hypothyroidism are Hashimoto's, the autoimmune form, where your body attacks your thyroid gland. The conventional standard of care is to check only TSH (thyroid-stimulating hormone), even though TSH doesn't identify an autoimmune disease. This episode is especially important if you've been struggling with thyroid symptoms and haven't been checked for thyroid autoimmunity. (This episode was originally released in Dec 2022)
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How Unexpressed Emotions Wreck Your Hormones (And How to Fix It)
Today's podcast guest, Dr. Sonya Jensen, is a first-generation immigrant who grew up navigating two very different cultures and the rules imposed on her about how she should look, who she should be friends with, and how she should perform in school. Around age 13, she developed anorexia as a way of gaining control of her own life. Ultimately, her experiences with anorexia, processing childhood trauma, and working with patients led her to put the pieces together between emotions, trauma, and physical health. In this episode, we discuss the deep work she does with women, where she focuses on the well-researched links between emotions and physical health. In this podcast, Dr. Jensen and I discuss: A 66,000-woman study over 16 years found every single woman with a fibroid had childhood abuse, whether physical, sexual, or emotional (this is when Dr. Jensen started piecing together trauma and physical health) When progesterone is low, GABA is low - so you may feel anxious - when estrogen is low, dopamine and serotonin are low, so you're not accessing joy as quickly Constant production of the stress hormone cortisol creates more pronounced estrogen dominance; one woman manifests tender breasts or cysts, another manifests fibroids, but all have low progesterone Fibroids can become worse by pseudo-estrogen from environmental toxins (pesticides, phthalates, plastics)...if your body can't detoxify them, they recirculate and create estrogen dominance Dr. Jensen was previously against bioidentical hormones, but she then realized women go into midlife very depleted, and physiological dosing helps them feel like themselves again Progesterone dosing is nuanced: One of Dr. Jensen's patients went into psychosis on progesterone because her OB-GYN doubled the dose - not everyone can be on the same dose or same kind of hormone Holocaust studies show infants born to survivors have adrenal insufficiency; their ability to adapt to stress isn't as optimal due to generational trauma If mom was stressed during pregnancy, her preteen will have more anxiety, if mom had really low cortisol, the child's nervous system regulation isn't as efficient Women who use hormones along with lifestyle changes and emotional work thrive on minimal doses, and some can even take breaks; women who only do hormones hit plateaus and cycle back
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Detox Your Body: The Hidden Toxins Destroying Your Energy with Wendie Trubow, MD
My guest today, Dr. Wendie Trubow, went to France in 2019 for the trip of a lifetime. But when she came home, her hair started falling out, she gained weight, and had a rash all over her face. She tested her thyroid (perfect), hormones (perfect), and gut (great). Ultimately, she realized that when Notre Dame burned, it released 500 tons of lead into the air and soil, and she had slogged through that dust for a week. Testing showed that her lead levels were incredibly high. Her biggest insight was that all the modern medical issues she treated as a functional MD—obesity, diabetes, cancer, insomnia, endocrine dysfunction, gut dysfunction—could be tracked back to toxic exposures, creating a state of inflammation. Dr. Trubow believes your particular "soup" (genetics, lifestyle, early childhood, antibiotic use, diet, sleep, stress, relationships, self-talk, movement) determines how inflammation manifests in you. Wendie's story is really incredible, and I think you'll love this podcast. This episode was first released in Jan 2023 In this podcast, Dr. Trubow and I discuss: How toxins are related to stubborn weight: they get stored in fatty tissue when you exceed your body's ability to excrete them Studies show that levels of persistent organic pollutants ("forever chemicals") in the bloodstream during weight loss predict weight regain! Alcohol is an acute toxin that takes priority in the liver—your body stops all other detox behavior (hormone processing, pesticide excretion) to focus exclusively on processing alcohol By the time most women leave the house, they've put over 200 chemicals on their bodies, from shampoo, conditioner, face products, makeup, moisturizers, and perfumes Your bed is a hidden toxin if it contains flame retardants—these are endocrine disruptors, mess up your thyroid and female hormones, and raise your risk of estrogen-dependent cancers Never ask "What-if?" questions…ruminating about uncontrollable situations sends your body into fight-flight-freeze and shuts down detox New cars contain over 300 chemicals, and even new clothes are sprayed with chemicals—wash clothes before you wear them, and shop consciously It's more expensive to react to disease than prevent it…if you could avoid cancer by spending $10 extra a day, it would be the right financial move; cancer costs most people over $100,000 per year to treat
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Dr. Shivani Gupta: The Inflammation Code and Ancient Ayurvedic Wisdom
Dr. Shivani Gupta comes from a family of people with diabetes, generation by generation, where she's seen the after-effects of suffering with chronic metabolic disease. Her new book, The Inflammation Code (launching, distills 20 years of studying Ayurveda into simple pillars you can apply to prevent the level of inflammation and disease we see today. When people tell her, "I have brain fog, I'm tired, my sleep is off, my digestion's off, I have stubborn weight gain…I guess this is just aging," her reply is, "No, it's not aging, it's inflammaging." We had a really excellent, in-depth conversation that covered a lot of ground, from black pepper and the blood-brain-barrier to our detox experiences in India. I hope you enjoy the podcast! In this podcast, Dr. Gupta and I discuss: Her study of Ayurveda, a 5,000-year-old system from India that taught us the circadian clock, modern science discovered what Ayurveda taught 5,000 years ago about living in rhythm with nature The three doshas or constitutions of Vata (air/ether), Pitta (fire/water), and Kapha (earth/water)—understanding your constitution helps customize your self-care practices and diet The circadian clock in Ayurveda teaches that 10:00 to 2:00 PM is Pitta (fire) time, when you're most focused and energetic, and meant to eat your biggest meal 10:00 PM to 2:00 AM is the most important time to be asleep, when Pitta fire cleans and clears inflammation, the lymphatic system, and the glymphatic system (lymphatic system of the brain) Vata people are always in motion and prefer jobs where they don't sit still—they're endurance athletes who can run through the day on coffee, green juice, and crackers (but their homework is three square meals) Pitta people are fiery, passionate leaders who tend to crave hot, oily, spicy fried food…but that's the one thing they shouldn't eat because their digestive fire is already like a bonfire! Kapha people are sturdy, strong, and very grounded, but can struggle with sluggish metabolism, low mood or depression, getting stuck, or not wanting to create change Black pepper increases curcumin absorption by 2,000%—scientists at MD Anderson Cancer Center discovered this, which is why traditional Indian cooking always uses turmeric with black pepper What it feels like to experience a Panchakarma detox in India: "massage that feels like abuse" with paper thongs—Dr. Gupta says, "I can't believe you're allowed to do this to me and I'm paying for it" (both she and I had this experience!) Mental inflammation is the stress we create when forcing ourselves to be healthy; if you force workouts, force protein, force intermittent fasting, the stress alone causes the inflammation you're trying to prevent
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Dr. Gabrielle Lyon: Forever Strong Playbook and Muscle-Centric Medicine
Dr. Gabrielle Lyon argues we've been focusing on the wrong idea for 50 years…the problem isn't that we're over-fat, it's that we're under-muscled. Skeletal muscle makes up 40% or more of your body and is an underrecognized endocrine organ that secretes myokines (signaling molecules) when contracted, impacting the brain, liver, pancreas, and truly every body system. Yet skeletal muscle wasn't even considered an organ system until about 25 years ago! The diseases we think of as obesity-related—type 2 diabetes, Alzheimer's, cardiovascular disease—are actually diseases of skeletal muscle first, decades before symptoms appear. When Dr. Lyon asked a PCOS expert what body fat percentage contributes to infertility, the answer shocked her: "It has nothing to do with body fat percentage—it has everything to do with the fat infiltrated into the muscle, the intermuscular adipose tissue (IMAT)." The new US Dietary Guidelines (which Dr. Lyon witnessed being announced on stage) recommend 1.2 to 1.6 grams of protein per kg for the first time in history, a tremendous change based on randomized controlled trials instead of epidemiology. Her mentor, Dr. Donald Layman, wrote the protein portion of the guidelines, and 90% of those guidelines are reflected in her new book, Forever Strong Playbook, released on January 27th of this year.
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Diaphragm to Pelvic Floor: The Forgotten Connection That Changes Everything with Jana Danielson
Over 30 million women in the US deal with some form of pelvic floor dysfunction…nearly 1 in 4 women. In this episode, I speak with Jana Danielson, founder of Lead Pilates and creator of the Cooch Ball (and no, that's not a typo!), who reveals shocking realities about the urinary incontinence product industry. Even though they'll top $24 billion in profit this year, 9 out of 10 people could fix incontinence if they learned to breathe correctly and stopped being such literal "tight asses" (her words, not mine). Listen to the podcast to hear all of Jana's insights. In this podcast, Jana and I discuss: Why over 30 million US women deal with pelvic floor dysfunction—nearly 1 in 4 women—and the urinary incontinence product industry will top $24 billion this year The pelvic floor can be too tight (hypertonic) or too loose (hypotonic)—too tight causes one set of symptoms, while too loose causes another About 90% of erectile dysfunction is actually a fitness/movement issue, not medical…when pelvic floor muscles get too tight, blood flow to the penis cannot happen There are four grades of prolapse; some grades can be completely reversed, while others require surgery. Jana explains the anatomical and energetic underpinnings of prolapse The diaphragm is the "roof" and the pelvic floor is the "floor" of your core—doing 10-12 diaphragmatic breaths daily will wake up the pelvic floor tissues, like giving it CPR The pudendal nerve's Latin root means "ashamed"—it's the main sensory and motor nerve from your brain to your genitals/pelvic floor in both men and women You can do all the fancy medical spa pelvic floor contractions, but without proper breathing, your results won't last—you have to create the environment for the solution to work When you inhale into your diaphragm, the pelvic floor is in its restful/descension phase—when you exhale, it's in its lift phase, a key distinction for pelvic floor health Posture plays a considerable role in pelvic floor health: mechanically holding weight in an optimal position takes unnecessary stress off your pelvic floor If you chug water rapidly, your body will excrete more of it. Sip tiny amounts throughout the day so cells absorb hydration properly and your bladder functions optimally
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The Secrets To A Happy Brain and Life with Dr. Loretta Breuning
In this episode, I am speaking with Dr. Loretta Breuning, who is the founder of the Inner Mammal Institute. She's the author of many personal development books, including the one that I have read of hers, which I highly recommend, and found fascinating, called Habits of a Happy Brain.
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Why Your Dentist Is Wrong About Toothpaste, Flossing, and Fluoride with Dr. Al Danenberg
Periodontist Dr. Al Danenberg was diagnosed with incurable bone marrow cancer (multiple myeloma) in September 2018 and given 3 to 6 months to live. His oncologist wanted to start chemotherapy the next day, but Dr. Al rejected chemo and instead focused on natural methods to help his body heal. While Dr. Danenberg has since passed on, he survived most of his remaining years with an outstanding quality of life, shocking his oncologist and maintaining such good health that his gut microbiome diversity was in the 97th percentile. In this episode, filmed in March 2023, Dr. Al discusses his diagnosis and why he believed his cancer stemmed from toxic exposures in dental school in the late 1960s and early 1970s. He emphasizes that all cancers are diseases of lifestyle, and that there are very few wild animals with cancer and very few primal societies with gum disease, tooth decay, chronic diseases, or cancer. Dr. Al also explores a few somewhat shocking oral health ideas, including why dental plaque is actually healthy! He backs this surprising claim with three critical roles plaque plays in the mouth: it acts as a gatekeeper, allowing minerals from saliva to remineralize teeth; it contains chemical buffers that keep pH at ~5.5 to prevent decay; and it produces hydrogen peroxide that kills pathogenic bacteria trying to invade. I know you'll enjoy this episode with the late Dr. Al Danenberg.
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Dr. Reef Karim: The Victim Mentality Epidemic and Path to Vulnerability
In this podcast, I am speaking with Dr. Reef Karim, a leading expert in human behavior, who has dedicated his life to educating, entertaining, and helping people understand themselves better. Dr. Karim is a double board certified psychiatrist, addiction medicine physician, relationship expert, writer, speaker (with recurring appearances on Oprah, Dr. Oz, CNN, Larry King Live, Dr. Phil, Anderson Cooper, and many others), comedic host, and media personality. We will discuss the "victim mindset" and how it appears to be rapidly spreading in the younger generations across the Western world, the difference between victimhood and vulnerability, conformism vs. authenticity/courage, healing from trauma, self-sabotaging behavior, and how to grow into the fullest expression of your own capacities and authentic self.
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How To Have Strong Bones and Prevent Osteoporosis with Margie Bissinger
Did you know that, in the United States alone, one in two women and one in four men over the age of 50 will have a fracture due to osteoporosis? And if this happens to be a hip fracture, 24% will die within a year due to complications, while an even higher percentage will never be independent again. The most unfortunate part is that conventional doctors typically just prescribe vitamin D, calcium, and maybe a non-specific form of exercise…then immediately put you on medication without examining root causes. In this episode, Margie Bissinger, a physical therapist with over 25 years of experience treating osteoporosis, reveals the real culprits behind the bone density epidemic, including sugar, gluten sensitivity and gut inflammation, proton-pump inhibitors like Nexium and Prilosec, corticosteroids, antidepressants, stress and cortisol, and sedentary behavior. Listen to the full episode to get all of Margie's actionable information to avoid or even begin reversing osteoporosis. This episode was initially released in March 2023
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Beyond Adrenal Fatigue: What's Really Happening With Your Cortisol with Dr. Izabella Wentz
Dr. Izabella Wentz is a renowned pharmacist focused on thyroid health. In this episode, she reveals a shocking pattern: about 90% of people with Hashimoto's have alterations in how much cortisol they release throughout the day. They struggle with brain fog, chronic fatigue, and sleep issues—tired all day, wired at night—even when they're on thyroid medications. She's discovered something fascinating about "adrenal fatigue" that challenges both the old naturopathic model and the skeptics. Your adrenals aren't damaged or lazy…they're perfectly capable of producing hormones. "Adrenal fatigue" is an intelligent adaptive response where your body down-regulates cortisol production to protect itself from chronic stress, essentially saying, "This is unrealistic, we can't pump out high amounts of cortisol all the time." After being forced to find solutions during years of severe sleep deprivation with her son, Dr. Wentz developed a 4-week protocol that has now helped thousands of people. By week two, people report their anxiety dropping from an 8 to a 2. By week four, their libido returns and they feel transformed, all without hormones, complicated testing, or bags full of supplements.
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From 1% to 20%: The Mental Health Crisis No One Talks About with Dr. Bonnie Kaplan
In this episode, Dr. Bonnie Kaplan shares a statistic that should stop everyone in their tracks: 50% of people will be diagnosed with a mental disorder at some point in their lifetime. When she was a kid in the 1950s, that rate was 1% or less. As a professor emeritus at the University of Calgary and co-author of The Better Brain, Dr. Kaplan has spent decades researching what went wrong. She shares the case of "Andrew," a 10-year-old with childhood psychosis who recovered on micronutrients when six months of psychiatric care failed…yet his doctor refused to try it with other patients because "it's not part of clinical practice guidelines." This episode was initially released in July 2022
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From Hot Flashes to Brain Fog: What's Really Happening in Perimenopause with Dr. Mariza Snyder
This interview took place on a historic day: the FDA removed the black box warning for HRT (hormone replacement therapy) after 20 years. My guest, Dr. Mariza Snyder, author of The Perimenopause Revolution, explains why this matters and why women have been suffering needlessly for decades while doctors dismissed their symptoms as "just aging" or "just stress." Perimenopause is the 4 to 10-year transition where hormones wildly fluctuate before menopause, and Dr. Snyder calls it "the window of vulnerability." She uses a powerful metaphor: imagine estrogen as your brain's master CEO who shows up like clockwork from 9 AM to 6 PM for 30 years. Then, suddenly, without warning, it shows up at 2 PM one day and leaves at 11 PM, then shows up at 6 AM the next day and leaves at 11 AM. Your brain scrambles trying to regulate energy, neurotransmitters, sleep, mood, and cravings. The most compelling insight of our conversation is a Mayo Clinic study that found 84% of menopausal women don't seek care. Why? Because they feel judged in the doctor's office. Dr. Snyder wrote her book as the roadmap she desperately needed when she started her own perimenopause journey, connecting symptoms to future health outcomes and providing practical solutions beyond just "you're getting older."
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Secrets of Melatonin and Methylene Blue with Dr. John Lieurance
In this episode with Dr. John Lieurance, he drops a bombshell in the first few minutes: "I take hundreds of milligrams [of melatonin] every night, and I've gone through months and months of taking it religiously." While most melatonin supplements contain a dose of 0.3 to 3 milligrams, Dr. Lieurance has 30 years of clinical experience and, during our conversation, shares his unorthodox but largely research-backed views on melatonin, methylene blue, and mitochondrial health. As one of the world's leading clinical experts on melatonin and methylene blue, Dr. Lieurance reveals findings that most people have never heard, including why melatonin is an amazing adaptogen and how it even prevents the Warburg effect that powers cancer cells. The second half of our conversation explores methylene blue, the original compound that inspired the term "magic bullet." Dr. Lieurance explains how this brilliant blue salt was discovered while searching for a malaria cure, how it increases mitochondrial function by an average of 30%, and why it acts as both a prooxidant and antioxidant. Most fascinating is the synergy with red light therapy…methylene blue absorbs 660-nanometer photons, supports cytochrome C oxidase, and creates powerful antimicrobial effects. He shares clinical dosing protocols, debunks FDA warnings, and explains why higher doses are more effective than the micro-doses commonly recommended. In this podcast, Dr. Lieurance and I discuss: His personal health journey and why he takes hundreds of milligrams of melatonin every night, while maintaining high testosterone levels, directly contradicting Andrew Huberman's warnings based on flawed rodent studies Melatonin studies that used up to 150,000 milligrams with zero toxicity found, yet recent claims suggest melatonin is toxic to kids, with little research to support it The fact that your gut produces 400 times more melatonin than the pineal gland! Every single cell produces its own melatonin within the mitochondria, a discovery that only emerged in the last couple years, completely reframing melatonin's importance The biological reason why you can take large amounts of melatonin for extended periods and stop the next day without suppression of natural production The connection between melatonin, hormesis, and your mitochondria How high-dose melatonin protects you from sun damage The interesting story of methylene blue, the original "magic bullet" discovered while curing malaria How methylene blue increases mitochondrial function by 30% on average
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The Mitochondrial Super Foods Actually Worth Eating with Dr. Chris Masterjohn
In this episode, Dr. Chris Masterjohn cuts through the noise with his refreshingly practical approach to nutrition for your mitochondria. He exposes supplement industry myths and explains why your mitochondria need more than just CoQ10 and alpha-lipoic acid. Plus, his insights into how your brain regulates energy metabolism will completely shift how you think about fatigue. Whether you're dealing with chronic exhaustion or just want to optimize your energy, this conversation delivers actionable wisdom—Dr. Masterjohn even shares his favorite "superfood cocktail." Get ready to question everything you thought you knew about mitochondrial nutrition! This episode was initially released in Sept 2023
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Why Mental Stress Is Your Heaviest Straw with Dr. Greg Kelly
What if curing cancer and heart disease wouldn't actually extend human lifespan by much? It sounds crazy, but this concept opens the door to my conversation with Dr. Greg Kelly, Director of Product Development at Neurohacker Collective and author of Shape Shift. The reason is simpler than you think: most people would still die in their mid-80s from accumulated cellular damage and "dying of old age," i.e., multi-organ failure from decades of cellular aging. Dr. Kelly brings a unique perspective, having served as a Navy officer before becoming a naturopathic physician and spending two decades in the trenches of longevity research. He shares a fascinating personal story about repaying his massive sleep debt from his military years—sleeping 12 hours a night for weeks until his chronically cold hands suddenly became warm. His insights on why catching up on sleep often makes us feel more tired will completely reframe how you think about recovery. This conversation goes deep into cellular senescence ("zombie cells" that accumulate as we age), the gut microbiome's role in longevity, why melatonin supplements are often misused, and which nootropics actually work. Dr. Kelly explains the "last straw" model of stress that will change how you view your health, and why chasing individual diseases instead of focusing on cellular aging is like rearranging deck chairs on the Titanic. This episode was initially released in July 2023
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Alzheimer's Is Optional | Preventing And Reversing Cognitive Decline with Dale Bredesen, MD
In this episode, I am speaking with Dr. Dale Bredesen about the root causes of cognitive decline and how to prevent and reverse them.
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How Do Mitochondria Respond To Health And Disease? | Eric D. Gordon, MD
What if your mitochondria aren't broken, but rather stuck in defense mode? What if chronic illness isn't about damaged cells, but about cells that can't sense safety anymore? Dr. Eric Gordon has spent over 40 years in the trenches of complex chronic illness, working with thousands of patients who didn't fit into conventional medicine's boxes. He's one of the deepest thinkers in functional medicine and an original voice who has witnessed and worked through every health fad out there. In this conversation, he explains why mitochondrial support sometimes backfires, why your body gets stuck in chronic illness patterns like a "neurotic loop," and most importantly, how to give your cells the safety signals they need to heal.
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Why Hormones Aren't the Boss: The Mitochondrial Truth About Thyroid Health with Dr. Eric Balcavage
In this episode, I am speaking with Dr. Eric Balcavage, who is a renowned thyroid health expert and author of the Thyroid Debacle. He also lectures around the country on various health topics including stem cell therapy and regenerative medicine, thyroid dysfunction, methylation dysfunction, and more.
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Healing The Nervous System Through Breath And Body with Rome Za
In this episode, I'm speaking with Rome Za, a movement specialist, Jiu-Jitsu athlete, father, and founder of the Rome Za method, a breathwork-based way to transform your nervous system. In this podcast, Rome and I discuss: His fascinating and sometimes very intense childhood, including an early brush with death The one factor we should focus on for nervous system healing before supplements or even diet Rome's vast experience coaching people and the recurrent issue he's seen in over 4,000 coaching clients 2 nervous system assaults you should be keenly aware of and how to address both for a calm, centered life The importance of non-traditional strength movements that lead to vitality, resilience, and longevity 3 core insights you can apply to your own life to support and steady your nervous system
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Muscle Is the Organ of Longevity: The Link Between Muscle Health and Mitochondria with Dr. Gabrielle Lyon
The key to longevity, energy, and metabolic health isn't found in your heart, liver, or brain…but in your muscles. Amazingly, your muscles make up the largest organ system in your body and, importantly, the primary home of your mitochondria. Dr. Gabrielle Lyon is a fellowship-trained physician in nutritional science and geriatrics who is revolutionizing our understanding of muscle as the organ of longevity. Her work reveals why skeletal muscle is the only organ system we have direct control over. In this conversation, she explains the shocking 400% difference in mitochondrial capacity between athletes and people with metabolic syndrome, why the "healthy sedentary" person doesn't exist, and her proven protocol for eating and training to optimize both muscle and mitochondrial health.
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From Cell Danger Response to Cellular Safety: A Revolutionary Approach to Trauma with Dr. Aimie Apigian
What if the popular narrative about trauma is incomplete? What if trauma isn't just a psychological phenomenon, but a fundamentally biological process that gets encoded in your cells, mitochondria, and nervous system? Dr. Aimie Apigian is a double board-certified physician in preventive and addiction medicine who's revolutionizing how we understand and treat trauma. Her groundbreaking new book, "The Biology of Trauma," reveals the hidden physiological mechanisms behind trauma responses. In this conversation, she explains where traditional talk therapy falls short, how trauma creates a feedback loop of oxidative stress and cellular shutdown, and her innovative approach to healing trauma from the inside out, starting with cellular safety before diving into the emotional work.
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Nutrition & Lifestyle vs. Medicine: The Best Approach to Your Health Part 1 with Dr. James Chestnut
In this episode, I am speaking with Dr. James Chestnut who is a doctor of chiropractic. He holds a bachelor of Physical Education and a Master of Science in Exercise Physiology specializing in neuromuscular adaptation. He holds a postgraduate certification in evidence-based chiropractic and lifestyle protocols. He has authored five books including his latest book Live Right for Your Species Type. In this part, we talk about the common misconceptions about the impact of nutrition and lifestyle on health and why it is much better than common drug treatment for long-term health.
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Reversing Alzheimer's Disease: Drugs vs. Lifestyle | Dr. Heather Sandison
In this episode, I'm speaking with Dr. Heather Sandison, a naturopathic doctor, published researcher, and the author of a new book you'll definitely want to read, Reversing Alzheimer's: The New Toolkit to Improve Cognition and Protect Brain Health. Dr. Sandison's work is extraordinary in many ways, but, in my opinion, one of her most impressive achievements is creating Marama Memory Care, the first residential memory care facility to have the goal of returning cognitively declined residents to independent living! I loved speaking with Dr. Sandison, and I know you'll learn a lot from this podcast. Enjoy!
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69
Borge Fagerli: The Myo-Reps Method and Why Most People Train Wrong
In this episode, I'm speaking with Børge Fagerli, creator of an innovative and highly efficient resistance training method called Myo-Reps, which is a way to create 80% of the results in a fraction of the time. Børge has spent over 25 years as a fitness coach and is known for his evidence-based approaches to nutrition, training, mindset, and lifestyle optimization. We became friends about 10 years ago (through a funny story you'll hear in the podcast) and we went on to have many years of fruitful discussions and debates on a variety of health topics, and worked together to produce content on the interface of nutrition and circadian rhythm. He's a great expert on fitness and body composition, and I think you'll gain a lot of insights from his thoughts on training. In this podcast, Børge and I discuss: His background as an engineer and bodybuilder and his research-backed reasons for focusing on fundamentals instead of getting caught up in wellness hype The 3 most essential factors you need to know to be successful in your exercise training…this is appropriate for ALL fitness levels! The number of exercise reps you should perform to see (and feel!) your body change and why this rep range is essential for women Why too many repetitions of one exercise might be the WRONG approach for most people The definitive answer to one of the most discussed questions in all of training: Will I get too big and bulky from lifting weights?? Why training that feels too hard or intense might actually be keeping you from achieving your goals If "muscle confusion," i.e., training your muscles with different exercises every time you work out, is a legitimate concept or pseudoscience Myo-Reps, Børge's strategy for achieving 40 minutes of exercise in just 20 minutes! The #1 mindset tip you can implement today to keep you strong and fit as you age
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68
Why Keto Works for Weight Loss But Fails for Performance with Dr. Mike T. Nelson
In this episode, Dr. Mike T. Nelson pulls back the curtain on some common keto myths, including how it's connected to fat loss, athletic performance, and even ancestral eating patterns. You might be surprised to learn that smart athletes will do anything to win—except go keto. In this myth-busting conversation, you'll discover why the high-fat-eating Inuit peoples probably weren't in ketosis, how keto can slash your power output by up to 8%, and why metabolic flexibility—not extreme diets—is the real key to optimal health. After 20-plus years in the field, Dr. Nelson shares his unfiltered take on everything from exogenous ketones to the carbohydrate hypothesis of obesity, delivering the nuanced truth that diet influencers won't tell you.
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67
Dr. Michael Murray: Flavonoids, Mitochondria, and Why Most Energy Supplements Miss the Mark
Did you know your mitochondria produce your body weight in ATP every single day? Dr. Michael Murray reveals why most people's "dimmer switch" is turned down and how flavonoids can actually repair damaged mitochondria, something once thought impossible. In this paradigm-shifting conversation, you'll discover why 80% of female endurance athletes are iron deficient, how nature designed a brilliant system for delivering flavonoids exactly where inflammation occurs, and why taking NAD+ supplements might be addressing the wrong problem entirely. After 45 years of studying flavonoids and treating thousands of patients, Dr. Murray shares his most powerful insights on what really drives energy production. This episode was originally released in November 2023
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66
The Hidden Link Between Your Microbiome and Mitochondria with Dr. Jason Hawrelak
Could your gut bacteria be producing toxins that poison your mitochondria? Dr. Jason Hawrelak, one of the world's leading microbiome researchers, reveals how specific bacterial imbalances directly sabotage your energy production. In this in-depth conversation, you'll discover why probiotics don't colonize your gut, why strain specificity matters more than you think, and why prebiotics are actually more powerful than probiotics for transforming your microbiome. Dr. Hawrelak's research has been cited over 1,200 times—he's the microbiome expert who teaches other experts—and his insights will completely change how you approach gut health.
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65
Dr. Scott Sherr: Methylene Blue, GABA, and the Hidden Link Between Mitochondria and Stress
Your mitochondria and responses to stress are more connected than you think. In this episode, Dr. Scott Sherr is back to tell us about why 94% of US adults have mitochondrial dysfunction and how chronic stress and inflammation deplete GABA, your brain's primary calming neurotransmitter. We also discuss why methylene blue has exploded from an obscure mitochondrial enhancer to a controversial biohacking trend, how GABA deficiency masquerades as anxiety and depression, and why healing requires shifting from sympathetic dominance to parasympathetic activation. Dr. Sherr shares his 20 years of clinical experience, demonstrating that within 30 seconds to 2 minutes, he can determine if someone can heal; it all comes down to the state of their nervous system.
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64
Healing Trauma at the Cellular Level with Dr. Keesha Ewers
We've created a culture that fears adversity, but what if that's the wrong approach? In this episode, Dr. Keesha Ewers explains why post-traumatic growth, not comfort, creates robust mitochondrial health and resilient humans. Her personal journey from autoimmune disease to vibrant health will inspire your own transformation and help you understand the mind-mitochondria connection. This episode was initially released in Jan 2024
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63
Alex Tarnava: Why Molecular Hydrogen Is Your Missing Energy Link
In this fascinating episode, I'm speaking with inventor and researcher Alex Tarnava, who developed the first effective-dose molecular hydrogen supplement to address a crippling mystery illness that suddenly destroyed his once highly active life. Our conversation reveals how initially skeptical we both were about the effectiveness of molecular hydrogen! While I'm extremely excited to offer Molecular Hydrogen, now available on the new Human Optimization site, it took me over 10 years, hundreds of research studies, and eventually experiencing the benefits myself to become a believer and trust the effects enough to offer this unique compound to you.
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62
Dr. Gabrielle Lyon - LONGEVITY Do This To BUILD MUSCLE & LIVE Longer!
In this episode, I'm speaking with Dr. Gabrielle Lyon, founder of the Institute for Muscle-Centric Medicine®, about her new book, Forever Strong. I believe Dr. Lyon's message is so crucial that I bought her book for myself and my parents—this episode is a must-listen! In this podcast, Dr. Lyon and I discuss: The completely overlooked driver of cardiovascular disease, cancer, Alzheimer's, and the epidemic of chronic illnesses…and it's a factor you can change TODAY Why worrying about fat gain is the wrong place to put your attention, and what to focus on instead "Calories in-calories out" and the real truth behind this hotly debated topic—plus, a deep dive into the macronutrient that can make or break body composition An evidence-based option for the over 40 million people on statin drugs…could cholesterol and triglycerides be managed without the risk of statin side effects? Why the "obesity epidemic" is completely inaccurate, and a new way to view obesity that will actually make a difference in people's lives Plus, why most seniors lose up to 75% of their mitochondrial capacity…and how you can avoid being part of that statistic
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61
From Heel Strike to Health: Minimalist Footwear Will Change Your Life with Steven Sashen
In this episode, I'm speaking with Steven Sashen, who founded minimalist shoe company Xero Shoes with his wife Lena Phoenix in 2009. His philosophy? Modern footwear is actively hurting you. In this discussion (which was so fun and informative thanks to Steven's lighthearted approach to his work), we explore what the shoe industry has been hiding about arch support, cushioning, and elevated heels, all while knowing these features actually increase injury rates. Steven's company exists because he wants to change people's lives, and after 16 years of challenging the footwear industry's biggest myths, he's revealing how traditional shoes weaken your feet, destabilize your balance, and even contribute to falls that kill older adults. Get ready to rethink everything you thought you knew about what to put on your feet. This conversation could literally save you from decades of unnecessary pain, injury, and disability.
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60
Heart rate variability, polyvagal theory, the flaw in trying to HACK the body, and more with Dr. Mel Hopper Koppelman
In this episode, I'm excited to welcome Dr. Mel Hopper Koppelman back for the third time! Today, we continue our conversation on the overlooked importance of brain development but go on to explore heart rate variability (and how it can easily be misinterpreted), Polyvagal Theory, and her fascinating, physics-based thoughts on how our heart rate variability connects us to the universe! In this podcast, Dr. Mel and I discuss: An easy way to visualize brain development: the brainstem is the root that grows up into the trunk of our brain and branches off into the right and left hemispheres The underlying driver of illness for many people with chronic symptoms and why gut or immune health might continue to suffer if this isn't addressed A clear, easy-to-understand explanation of heart rate variability and why this often-misinterpreted marker is crucial for vital health The 10-second at-home test Dr. Mel recommends to better understand your heart rate variability findings AND the functioning of your vagus nerve! Her physics-backed belief that our heart rate variability connects us to the "breath" or wave of the universe…and how this connection (or lack of connection!) relates to the vagus nerve, inflammation, nervous system development, and long-term health 2 major predictors of mortality, i.e., how long you will live and the interesting pattern often found in people with autism The extreme importance of working with the body and tracking test results versus cleverly attempting to biohack or manipulate the body with supplements or drugs
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59
Your 2 Brains And The Link To ADHD, Autism, Anxiety, And Autoimmunity with Dr. Mel Hopper Koppelman
In this episode, I'm back with Dr. Mel Hopper Koppelman, discussing what she believes is one of the most important and overlooked areas in health—how brain development in childhood might be at the root of the health problems you're experiencing as an adult. You'll likely have some 'aha!' moments (maybe big ones) while listening to the podcast. In this podcast, Dr. Mel and I discuss: The fascinating fact that we actually have 2 brains…and how brain imbalances impact your immune system and overall health How evolution led to our specialized, complex brain design and the main purposes it serves Myths debunked: The misunderstood idea that the left brain controls math and logic and the right brain controls creativity, and whether it's true that we only use 10% of our brain The overlooked brain imbalance called "functional disconnection" and why this might be at the root of health problems such as autism, ADHD, gut dysfunction, autoimmunity, dyslexia, depression, anxiety, or even chronic infections The surprisingly easy-to-test primitive reflexes (that start in the womb!) and how they're connected to chronic disease Could you have an immature brain stem? Dr. Mel tells us the symptoms that let you know AND how to address this issue Why some popular health solutions might actually make you worse based on the specific brain imbalance you're experiencing How brain imbalance can lead to changes in blood tests, such as low white blood cell count Practical ways you can assess if you have an imbalanced brain, accounting for your particular skills, health history, and childhood experiences The important distinction between pathologizing neurodiversity vs. helping those who wish to improve their brain's functionality in certain areas The liberating knowledge that our brains are malleable and trainable, and we can heal even longstanding brain-related issues!
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58
Performance Lifestyle: Live a High-Performance Life Without Burning Out with John A. Mollenhauer
After 25 years of being "Superman on the outside but a train wreck on the inside," John A. Mollenhauer has discovered the missing piece between high achievement and sustainable health. John is an entrepreneur who started his first gym at 19 and worked with Tony Robbins in his 20s—he learned the hard way that our culture rewards the very behaviors that lead to burnout. In this episode, John reveals how he developed the Performance Lifestyle framework after checking himself into a hospital from complete exhaustion. His method isn't about work-life balance—it's about knowing what to do, why, how, and when at the right intensity for sustainable results in both health and achievement. This conversation offers a practical pathway to break free from the hidden lifestyle challenges keeping you stuck in the energy-debt cycle.
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57
A Detailed Practical Guide to Dosing Red and Near-Infrared Light Therapy with Dr. Mark Cronshaw
I'm back again for my fourth conversation with Dr. Mark Cronshaw, an expert in the world of photobiomodulation (PBM), aka red light therapy. You know that when I have multiple conversations with a guest, I highly value their knowledge and want to go deeper with what they have to share. If you want to get VERY technical and go deep with the topic of PBM, this episode is for you, and I recommend you listen to the prior 3 episodes we've recorded together. In this conversation, Dr. Cronshaw presents what he calls his "philosophy of care" for using photobiomodulation to enhance healing, manage pain, and prevent injury. His approach focuses on a few fundamental questions: Are you treating surface or deep tissues? Are you seeking to stimulate healing/tissue repair or provide pain relief? His multi-dimensional approach explains why different devices produce different results, enabling more strategic use of both professional and at-home light therapy tools.
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56
Beyond Red Light: Dr. Cronshaw's Revolutionary Approach to PBM Therapy
In this episode, I'm back for a third installment of my conversation with Dr. Mark Cronshaw, one of the world's foremost photobiomodulation (PBM) experts...what most people commonly refer to as red light therapy. He's particularly one of the top experts when it comes to dosimetry (the details of how to properly "dose" light therapy). Have you invested in red light therapy but feel confused by contradicting information? You're certainly not alone. In this conversation, Dr. Cronshaw challenges conventional wisdom about photobiomodulation with some insights that surprised even me! I deeply appreciate his highly informed and logical, yet relaxed, approach to this complex topic. WARNING: My conversations with Dr. Cronshaw are NOT a simple or practical how-to guide of "go buy this device and use it this way." This podcast series intends to go deep into the scientific, technical, and theoretical nuances of PBM science. So it's NOT for everyone. These podcasts are for people who want to nerd out on PBM science. So please don't say I didn't warn you! :)
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55
The Connection Code: Transforming Women's Lives in Just Minutes a Day with Dr. Melissa Sonners
In this episode of The Energy Blueprint podcast, I'm speaking with Dr. Melissa Sonners, host of the Be Inspired Mama podcast and creator of a movement that's transforming how women approach self-care. After battling Lyme disease and mold toxicity while juggling motherhood, a chiropractic practice, and the pressure to "do it all," Dr. Sonners discovered that traditional self-care wasn't the answer—it was self-CONNECTION. Her practical approach helps busy women transform their relationship with themselves without adding more to their overflowing plates. This conversation is essential for any woman feeling overwhelmed by life's demands.
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54
Sunlight Secrets: Debunking Skincare Myths with Nadine Artemis
In this episode, I'm speaking with Nadine Artemis, author of Renegade Beauty and Holistic Dental Care. But most personally impactful to me is that she's the woman behind Living Libations, an obsessively natural skincare line that has been creating and promoting pure products for over 30 years. My family and I really love and frequently use her products.
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53
How diet can help kids with autism, ADHD, anxiety and more… With researcher Julie Matthews
In this episode, I'm speaking with Julie Matthews, a Certified Nutrition Consultant and published researcher specializing in personalized nutrition for complex neurological conditions, particularly autism spectrum disorder and ADHD.
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52
How the Brooklyn Bridge led to Hyperbaric Oxygen Therapy with Scott Sherr, MD
In this episode, I'm speaking with Dr. Scott Sherr, a board-certified internal medicine physician certified to practice Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy (HBOT).
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51
Why the nervous system is the key to unlocking performance and recovery with Dr. Sean Drake
In this episode, I'm speaking with Dr. Sean Drake, a highly accomplished chiropractor with a fascinating career and life. His work now focuses on helping athletes, but don't stop reading just because you're not a high-level athlete. The beauty of Dr. Drake's strategies is that they apply to everyone. I actually love what he says in the interview…"Everybody's an athlete. If you have a body, you're an athlete." At the core of his approach is that modulating the nervous system holds the key to unlocking extraordinary performance and healing.
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ABOUT THIS SHOW
The go-to source for the latest cutting-edge science on overcoming fatigue and increasing your energy. The Energy Blueprint podcast brings together the world's leading researchers, doctors, and nutrition and lifestyle experts on the subject of fatigue and energy to help you get your energy back.
HOSTED BY
Ari Whitten
CATEGORIES
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