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All Episodes

GHAPPcast — 150 episodes

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Title
1

Medication Review: Stable PK Supporting Continuous Inflammatory Control

2

ASTRO Phase 3 Study: Efficacy and Safety of SC Guselkumab

3

Journal Club: Benefit–Risk Profile of Upadacitinib in Patient’s With Moderate to Severe UC and CD

4

Podcast: How Do You Best Support Patients Getting Started on New MASH Treatments?

5

Podcast: Best Practices For Patient Identification

6

SubQ Solutions: Induction and Maintenance in Moderately to Severely Active CD and UC

7

FAQ: Treat Through VS Randomized Withdrawal Design: What's The Difference?

8

Medication Review: GALAXI & GRAVITI Clinical Trials & LTE Data

9

Podcast: Inflammation Intersection: A Rheum-Gi Dialogue

10

Journal Club: Risankizumab Long-Term Efficacy in Crohn’s Disease: FORTIFY Extension Results

11

Podcast: Upadacitinib FDA Label Update: What Clinicians Need to Know

12

FAQ: Biomarkers: The Non-Invasive Future of HCC Detection

13

FAQ: Approved Systemic Therapy in Upadacitinib’s Expanded UC and CD Indications

14

FAQ: What Does Clinically Inadvisable Mean in Upadacitinib’s Expanded UC and CD Indications?

15

FAQ: How Do You Balance Systemic and Liver Directed Therapies in Patients With MASH?

16

FAQ: What is the Relevance of Assessing Alcohol Consumption in Patients With MASH?

17

Medication Review: Resmetirom: Thyroid Hormone Receptor-β Agonism in MASH Treatment

18

APP Roundtable: Approach To Starting Treatments in Patients With CHB

19

APP Roundtable: Navigating Difficult Conversations in CHB

20

APP Roundtable: Addressing Co-Morbidities in CHB

21

FAQ: What Role Do NITs Play in Risk Stratification & Patient Selection—& Balancing Patient History?

22

Journal Club: Review of Focused Recommendations for the Management of MASLD

23

Medication Review: Resmetirom: Core Efficacy Data and Patient Selection Considerations

24

FAQ: What Are The Functional And Prognostic Differences Between Fibrosis F3 And F4 Patients?

25

The Conversation That Matters: Talking to Patients About Obesity and IMIDs

26

From Insight to Action: Practical Strategies to Improve Outcomes in Patients with Obesity and IMIDs

27

GHAPPcast: Women of Childbearing Age With IBD

28

The Hidden Costs: Obesity’s Role in Suboptimal Outcomes and Healthcare Burden in IMIDs

29

FAQ: How Do You Explain Remission To A Patient?

30

GHAPPcast: Mental and Sexual Health Concerns & How To Address Them For Your IBD Patient

31

Obesity and IMIDs: Unpacking the Epidemic and Its Far-Reaching Impacts

32

APP Insight: How Do You Develop a Treatment Plan for IBS-C? What Are Some Considerations?

33

GHAPPcast: IBS-C Therapies Explained: Helping Patients Understand Their Options

34

GHAPPcast: Smarter Surveillance: The Rise of Algorithms like GALAD and Their Path to Practice

35

FAQ: What Is the Importance of Biomarkers Such as Fecal Calprotectin and CRP?

36

FAQ: What Are the Next Steps When a Patient Still Has Active Disease When Taking Advanced Therapy?

37

APP Roundtable: Community Resources and Support Systems for CHB

38

APP Insight: Conducting Meaningful Conversations to Assess Therapy Impact

39

GHAPPcast: Decoding Diagnostics: Why Biomarker Development Phases Are Your Clinical Ally

40

GHAPPcast: Explaining IBS-C: Diagnosis and Communication That Builds Confidence

41

APP Insight: Evaluating Time to Response and Treatment Effectiveness

42

APP Insight: Why Is It Important to Let Patients Know There Are Different Options for Treatment?

43

Empowering PBC Patients: APPs’ Role in Education and Support

44

GHAPPcast: Payer Tutorial

45

APP Roundtable: Navigating Treatment Guidelines With CHB

46

APP Roundtable: Patient-Centric Care Approaches in PBC

47

APP Roundtable: Addressing Mental Health in Patients With PBC

48

GHAPPcast: Setting the Standard in Biomarker Validation: EDRN Example & Lessons from Liver Cancer

49

GHAPPcast: Navigating Difficult Conversations: Discussing prognosis and lifelong care in PBC

50

GHAPPcast: Collaborating Across Specialties: How APPs Can Work with Hepatologists & Other Providers in PBC Care

51

GHAPPcast: Managing PBC Symptoms in the Real World: Practical Tips for APPs

52

FAQ: What Is the Difference Between CIC and IBS-C?

53

GHAPPcast: Lifestyle and Nutrition Interventions for Constipation

54

APP Insight: Discussing Exercise as a Complement to IBS-C Treatment

55

GHAPPcast: Mental Health Issues and Symptoms Related to IBS-C

56

FAQ: What Is the Significance of Alarm Symptoms Including Pathophysiology?

57

APP Roundtable: Future Directions in CHB Research

58

APP Roundtable: Navigating Treatment Guidelines in CHB

59

APP Insight: Provide Diagnostic Tips for IBS-C

60

APP Insight: Using the Bristol Stool Scale to Measure Response to Treatment

61

APP Roundtable: Challenges in Diagnosing CHB

62

APP Roundtable: Future Directions in PBC Research

63

APP Roundtable: Multidisciplinary Care Models in PBC Management

64

APP Roundtable: PBC Patient Perspectives & Advocacy

65

FAQ: What Are the Main Causes of IBS, and How Does the Disease Progress Over Time?

66

KOL Conversation: Setting Expectations When Initiating New Therapy

67

KOL Conversation: Diagnosing IBS With Confidence

68

KOL Conversation: Diagnosing EPI and Managing With The Appropriate PERT Dosing

69

KOL Conversation: Implementing the IBS Guidelines

70

GHAPPcast: The Clinical Utility of Guselkumab in CD

71

GHAPPcast: Not Responding to UDCA in the First Few Months, Need to Move on to Second-Line Therapy

72

GHAPPcast: Need for Earlier Evaluation of UDCA Response, Need for Earlier Consideration of Second-Line Therapy

73

GHAPPcast: Building a Sense of Urgency for PBC Patient Evaluation/Monitoring

74

GHAPPcast: Importance of Understanding Impact on Disease Outcomes: Progression to Fibrosis and Cirrhosis

75

GHAPPcast: Need for Clinicians to Better Understand The "Area Under the Curve" in Non-Response to UDCA

76

GHAPPcast: Unable to Differentiate/Identify Between Slow & Fast Progressors - Need to Manage More Aggressively

77

GHAPPcast: Better Understanding of PBC Patients Overall Liver Health and Managing Patients Holistically

78

GHAPPcast: Biomarkers Beyond ALP to Monitor for Measuring PBC UDCA Response to Therapy and Disease Progression

79

Journal Club: Week 48 Efficacy of Guselkumab vs. Ustekinumab in Crohn’s Disease: Insights from GALAXI 2 & 3

80

GHAPPcast: Simplifying Access: Evolving Drug Distribution Channels

81

GHAPPcast: Simplifying Access: Prior Authorization Part 2

82

GHAPPcast: Simplifying Access: Prior Authorization Part 1

83

Journal Club: Efficacy & Safety of Subcutaneous Guselkumab: 48-Week Results from the Phase 3 GRAVITI Study

84

GHAPPcast: The Clinical Utility of Guselkumab in UC

85

KOL: What Are the Most Critical Updates in Cirrhosis Research That Clinicians Should Be Aware Of?

86

KOL: How Can Healthcare Professionals Improve Patient Outcomes in Those with Cirrhosis?

87

Journal Club: Efficacy and Safety of Guselkumab in Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results

88

FAQ: How does the guselkumab data align with the STRIDE II guidelines?

89

Medication Review: What are guselkumab's other FDA indications and how might that affect patient care?

90

KOL Interview: Can You Discuss Any Recent Breakthroughs in the Management of Cirrhosis?

91

FAQ: What should patients know about living with cirrhosis?

92

FAQ: What are predictive risk factors for disease severity in CD and UC?

93

FAQ: What lifestyle changes are essential for managing cirrhosis effectively?

94

Journal Club: Guselkumab Efficacy & Safety in Moderate to Severe CD-GALAXI 2 & 3 Results

95

FAQ: How Can You Support a Shared Decision-Making Process With the Patient?

96

Medication Review: What is the efficacy of guselkumab in ulcerative colitis and Crohn's disease?

97

FAQ: How can physicians better care for patients with cirrhosis?

98

Medication Review: What is the safety profile of guselkumab in ulcerative colitis and Crohn's disease?

99

Journal Club: Guselkumab for the Treatment of Crohn's Disease: Induction Results From the Phase 2 GALAXI-1 Study

100

GHAPPcast Part 3: Provider & Patient Support

101

FAQ: Is there a correlation of myeloid cells expressing CD64 and endoscopy disease severity?

102

GHAPPcast Part 2: Diagnosis and Management

103

FAQ: Why is binding CD64+ important when discussing IL23 directed therapy?

104

GHAPPcast Part 1: Understanding Chronic Liver Disease and Cirrhosis

105

Medication Review: How is guselkumab dosed in IBD?

106

GHAPPcast: CD64+ Binding: Description, Relevance, and Potential Clinical Implications

107

FAQ: Provide immunologic rationale for IL23 directed therapy in IBD(+ general overview of Guselkumab MOA)

108

Journal Club: Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis

109

Medication Review: What is non-responder imputation and how is it utilized in clinical trials?

110

FAQ: What is the role of IL23/IL17 axis in IBD

111

FAQ: Describe the IL23/IL17 axis

112

GHAPPcast: The IL23/IL17 Cascade and Implications in the Pathogenesis of IBD

113

Medication Review: Describe the mechanism of action of guselkumab

114

FAQ: Define, compare, and contrast humoral and cell-mediated immunity.

115

GHAPPcast: CSID in Adults: Clinical Pearls & the Patient Journey

116

GHAPP PBC Podcast Series Part 2: New Therapeutics In The PBC Space

117

GHAPP PBC Podcast Series Part 1: Prevalence, Awareness and Identification of PBC

118

GHAPP PBC Podcast Series Part 3: The Key Highlights of PBC at the GHAPP Conference 2024

119

KOL Conversation: A New Treatment Option

120

KOL Conversation: New & Emerging Treatment Considerations for PBC & PBC Pruritus

121

Journal Club: A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis

122

FAQ: What is MASH?

123

Medication Review Video Module: What is Resmetirom and how does it work to treat MASH?

124

FAQ: What are the consequences of NASH going untreated?

125

FAQ: How is MASH severity staged? What would an ideal MASH NIT algorithm look like?

126

Medication Review: What is the clinical profile of Resmetirom, including dosing schedules?

127

GHAPPcast: Recognizing the Severity of MASH

128

FAQ: Best practices to accelerate the time to finding the right therapy for your patients with IBS-C?

129

GHAPPcast: Navigating IBS: Pathophysiology, Neuromodulators, and Patient-Centered Care

130

FAQ: What does it mean for a biosimilar to be interchangeable and why is that important?

131

FAQ: What resources do you use to understand the latest approaches to managing IBS-C patients?

132

FAQ: What are some best practices in determining clinically meaningful “response” to therapy for IBS-C patients?

133

GHAPPcast: Biosimilars and the Patient Perspective

134

GHAPPcast: Mastering IBS-C: Diagnostic Strategies, Differentiation, and Management.

135

FAQ: What is the Difference Between Biosimilars and Generics?

136

FAQ: What Role Does a New Mechanism of Action Play in Your Prescribing Decisions of IBS-C Therapy?

137

GHAPPcast: Biosimilars Unveiled: Empowering APPs for Better Patient Conversations

138

CLDF/GHAPP Roundtable Podcast Series: MASH with Nadege Gunn, MD, Elizabeth Goacher, PA, and Ann Moore, FNP

139

Discussing Biosimilars With Patients

140

The Nocebo Effect

141

The Practical Use of Biosimilars in Gastroenterology APP Practice

142

The Practical Use of Biosimilars in Rheumatology APP Practice

143

The Benefits of Biosimilars

144

Managed Care and Biosimilars

145

Interchangeability & Switching of Biosimilars

146

Biosimilar Extrapolation

147

The Difference Between Biosimilars & Generic Drugs

148

The Regulatory Pathway to Biosimilar Approval

149

Development of Biosimilars

150

Biosimilars Series: What Are Biosimilars?