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All Episodes

GHAPPcast — 162 episodes

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Title
1

Podcast: How to Screen and Diagnose Cholestatic Liver Diseases

2

GHAPPcast: Recognizing and Managing Overt Hepatic Encephalopathy

3

FAQ: Counseling Patients on Overt Hepatic Encephalopathy

4

FAQ: Identifying & Diagnosing Overt Hepatic Encephalopathy

5

Subgroup Analysis: Differences in Maintenance Dosing For UC and CD

6

Medication Review: Efficacy & Safety of Risankizumab in Patients with Moderate to Severely Active UC

7

Med Review: SEQUENCE Trial: Risankizumab vs Ustekinumab in Anti-TNF-Refractory Crohn’s Disease

8

FAQ: QUASAR Long Term Extension Interim Analysis

9

Medication Review: Guselkumab IV vs SC Formulation

10

FAQ: Recognizing OHE Risk in Patients with Chronic Liver Disease

11

FAQ: Phase 3 GALAXI 2 & 3: Extraintestinal Manifestations In Moderate to Severe Crohn’s Disease

12

Medication Review: Monotherapy vs. Combination Therapy: Relevance in IBD Treatment Strategy

13

Medication Review: Stable PK Supporting Continuous Inflammatory Control

14

Journal Club: ASTRO Phase 3 Study: Efficacy and Safety of SC Guselkumab

15

Journal Club: Benefit–Risk Profile of Upadacitinib in Patient’s With Moderate to Severe UC and CD

16

Podcast: How Do You Best Support Patients Getting Started on New MASH Treatments?

17

Podcast: Best Practices For Patient Identification

18

Podcast: SubQ Solutions: Induction and Maintenance in Moderately to Severely Active CD and UC

19

FAQ: Treat Through VS Randomized Withdrawal Design: What's The Difference?

20

Medication Review: GALAXI & GRAVITI Clinical Trials & LTE Data

21

Podcast: Inflammation Intersection: A Rheum-Gi Dialogue

22

Journal Club: Risankizumab Long-Term Efficacy in Crohn’s Disease: FORTIFY Extension Results

23

Podcast: Upadacitinib FDA Label Update: What Clinicians Need to Know

24

FAQ: Biomarkers: The Non-Invasive Future of HCC Detection

25

FAQ: Approved Systemic Therapy in Upadacitinib’s Expanded UC and CD Indications

26

FAQ: What Does Clinically Inadvisable Mean in Upadacitinib’s Expanded UC and CD Indications?

27

FAQ: How Do You Balance Systemic and Liver Directed Therapies in Patients With MASH?

28

FAQ: What is the Relevance of Assessing Alcohol Consumption in Patients With MASH?

29

Medication Review: Resmetirom: Thyroid Hormone Receptor-β Agonism in MASH Treatment

30

APP Roundtable: Approach To Starting Treatments in Patients With CHB

31

APP Roundtable: Navigating Difficult Conversations in CHB

32

APP Roundtable: Addressing Co-Morbidities in CHB

33

FAQ: What Role Do NITs Play in Risk Stratification & Patient Selection—& Balancing Patient History?

34

Journal Club: Review of Focused Recommendations for the Management of MASLD

35

Medication Review: Resmetirom: Core Efficacy Data and Patient Selection Considerations

36

FAQ: What Are The Functional And Prognostic Differences Between Fibrosis F3 And F4 Patients?

37

The Conversation That Matters: Talking to Patients About Obesity and IMIDs

38

From Insight to Action: Practical Strategies to Improve Outcomes in Patients with Obesity and IMIDs

39

GHAPPcast: Women of Childbearing Age With IBD

40

The Hidden Costs: Obesity’s Role in Suboptimal Outcomes and Healthcare Burden in IMIDs

41

FAQ: How Do You Explain Remission To A Patient?

42

GHAPPcast: Mental and Sexual Health Concerns & How To Address Them For Your IBD Patient

43

Obesity and IMIDs: Unpacking the Epidemic and Its Far-Reaching Impacts

44

APP Insight: How Do You Develop a Treatment Plan for IBS-C? What Are Some Considerations?

45

GHAPPcast: IBS-C Therapies Explained: Helping Patients Understand Their Options

46

GHAPPcast: Smarter Surveillance: The Rise of Algorithms like GALAD and Their Path to Practice

47

FAQ: What Is the Importance of Biomarkers Such as Fecal Calprotectin and CRP?

48

FAQ: What Are the Next Steps When a Patient Still Has Active Disease When Taking Advanced Therapy?

49

APP Roundtable: Community Resources and Support Systems for CHB

50

APP Insight: Conducting Meaningful Conversations to Assess Therapy Impact

51

GHAPPcast: Decoding Diagnostics: Why Biomarker Development Phases Are Your Clinical Ally

52

GHAPPcast: Explaining IBS-C: Diagnosis and Communication That Builds Confidence

53

APP Insight: Evaluating Time to Response and Treatment Effectiveness

54

APP Insight: Why Is It Important to Let Patients Know There Are Different Options for Treatment?

55

Empowering PBC Patients: APPs’ Role in Education and Support

56

GHAPPcast: Payer Tutorial

57

APP Roundtable: Navigating Treatment Guidelines With CHB

58

APP Roundtable: Patient-Centric Care Approaches in PBC

59

APP Roundtable: Addressing Mental Health in Patients With PBC

60

GHAPPcast: Setting the Standard in Biomarker Validation: EDRN Example & Lessons from Liver Cancer

61

GHAPPcast: Navigating Difficult Conversations: Discussing prognosis and lifelong care in PBC

62

GHAPPcast: Collaborating Across Specialties: How APPs Can Work with Hepatologists & Other Providers in PBC Care

63

GHAPPcast: Managing PBC Symptoms in the Real World: Practical Tips for APPs

64

FAQ: What Is the Difference Between CIC and IBS-C?

65

GHAPPcast: Lifestyle and Nutrition Interventions for Constipation

66

APP Insight: Discussing Exercise as a Complement to IBS-C Treatment

67

GHAPPcast: Mental Health Issues and Symptoms Related to IBS-C

68

FAQ: What Is the Significance of Alarm Symptoms Including Pathophysiology?

69

APP Roundtable: Future Directions in CHB Research

70

APP Roundtable: Navigating Treatment Guidelines in CHB

71

APP Insight: Provide Diagnostic Tips for IBS-C

72

APP Insight: Using the Bristol Stool Scale to Measure Response to Treatment

73

APP Roundtable: Challenges in Diagnosing CHB

74

APP Roundtable: Future Directions in PBC Research

75

APP Roundtable: Multidisciplinary Care Models in PBC Management

76

APP Roundtable: PBC Patient Perspectives & Advocacy

77

FAQ: What Are the Main Causes of IBS, and How Does the Disease Progress Over Time?

78

KOL Conversation: Setting Expectations When Initiating New Therapy

79

KOL Conversation: Diagnosing IBS With Confidence

80

KOL Conversation: Diagnosing EPI and Managing With The Appropriate PERT Dosing

81

KOL Conversation: Implementing the IBS Guidelines

82

GHAPPcast: The Clinical Utility of Guselkumab in CD

83

GHAPPcast: Not Responding to UDCA in the First Few Months, Need to Move on to Second-Line Therapy

84

GHAPPcast: Need for Earlier Evaluation of UDCA Response, Need for Earlier Consideration of Second-Line Therapy

85

GHAPPcast: Building a Sense of Urgency for PBC Patient Evaluation/Monitoring

86

GHAPPcast: Importance of Understanding Impact on Disease Outcomes: Progression to Fibrosis and Cirrhosis

87

GHAPPcast: Need for Clinicians to Better Understand The "Area Under the Curve" in Non-Response to UDCA

88

GHAPPcast: Unable to Differentiate/Identify Between Slow & Fast Progressors - Need to Manage More Aggressively

89

GHAPPcast: Better Understanding of PBC Patients Overall Liver Health and Managing Patients Holistically

90

GHAPPcast: Biomarkers Beyond ALP to Monitor for Measuring PBC UDCA Response to Therapy and Disease Progression

91

Journal Club: Week 48 Efficacy of Guselkumab vs. Ustekinumab in Crohn’s Disease: Insights from GALAXI 2 & 3

92

GHAPPcast: Simplifying Access: Evolving Drug Distribution Channels

93

GHAPPcast: Simplifying Access: Prior Authorization Part 2

94

GHAPPcast: Simplifying Access: Prior Authorization Part 1

95

Journal Club: Efficacy & Safety of Subcutaneous Guselkumab: 48-Week Results from the Phase 3 GRAVITI Study

96

GHAPPcast: The Clinical Utility of Guselkumab in UC

97

KOL: What Are the Most Critical Updates in Cirrhosis Research That Clinicians Should Be Aware Of?

98

KOL: How Can Healthcare Professionals Improve Patient Outcomes in Those with Cirrhosis?

99

Journal Club: Efficacy and Safety of Guselkumab in Ulcerative Colitis: Phase 3 QUASAR Maintenance Study Results

100

FAQ: How does the guselkumab data align with the STRIDE II guidelines?

101

Medication Review: What are guselkumab's other FDA indications and how might that affect patient care?

102

KOL Interview: Can You Discuss Any Recent Breakthroughs in the Management of Cirrhosis?

103

FAQ: What should patients know about living with cirrhosis?

104

FAQ: What are predictive risk factors for disease severity in CD and UC?

105

FAQ: What lifestyle changes are essential for managing cirrhosis effectively?

106

Journal Club: Guselkumab Efficacy & Safety in Moderate to Severe CD-GALAXI 2 & 3 Results

107

FAQ: How Can You Support a Shared Decision-Making Process With the Patient?

108

Medication Review: What is the efficacy of guselkumab in ulcerative colitis and Crohn's disease?

109

FAQ: How can physicians better care for patients with cirrhosis?

110

Medication Review: What is the safety profile of guselkumab in ulcerative colitis and Crohn's disease?

111

Journal Club: Guselkumab for the Treatment of Crohn's Disease: Induction Results From the Phase 2 GALAXI-1 Study

112

GHAPPcast Part 3: Provider & Patient Support

113

FAQ: Is there a correlation of myeloid cells expressing CD64 and endoscopy disease severity?

114

GHAPPcast Part 2: Diagnosis and Management

115

FAQ: Why is binding CD64+ important when discussing IL23 directed therapy?

116

GHAPPcast Part 1: Understanding Chronic Liver Disease and Cirrhosis

117

Medication Review: How is guselkumab dosed in IBD?

118

GHAPPcast: CD64+ Binding: Description, Relevance, and Potential Clinical Implications

119

FAQ: Provide immunologic rationale for IL23 directed therapy in IBD(+ general overview of Guselkumab MOA)

120

Journal Club: Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis

121

Medication Review: What is non-responder imputation and how is it utilized in clinical trials?

122

FAQ: What is the role of IL23/IL17 axis in IBD

123

FAQ: Describe the IL23/IL17 axis

124

GHAPPcast: The IL23/IL17 Cascade and Implications in the Pathogenesis of IBD

125

Medication Review: Describe the mechanism of action of guselkumab

126

FAQ: Define, compare, and contrast humoral and cell-mediated immunity.

127

GHAPPcast: CSID in Adults: Clinical Pearls & the Patient Journey

128

GHAPP PBC Podcast Series Part 2: New Therapeutics In The PBC Space

129

GHAPP PBC Podcast Series Part 1: Prevalence, Awareness and Identification of PBC

130

GHAPP PBC Podcast Series Part 3: The Key Highlights of PBC at the GHAPP Conference 2024

131

KOL Conversation: A New Treatment Option

132

KOL Conversation: New & Emerging Treatment Considerations for PBC & PBC Pruritus

133

Journal Club: A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis

134

FAQ: What is MASH?

135

Medication Review Video Module: What is Resmetirom and how does it work to treat MASH?

136

FAQ: What are the consequences of NASH going untreated?

137

FAQ: How is MASH severity staged? What would an ideal MASH NIT algorithm look like?

138

Medication Review: What is the clinical profile of Resmetirom, including dosing schedules?

139

GHAPPcast: Recognizing the Severity of MASH

140

FAQ: Best practices to accelerate the time to finding the right therapy for your patients with IBS-C?

141

GHAPPcast: Navigating IBS: Pathophysiology, Neuromodulators, and Patient-Centered Care

142

FAQ: What does it mean for a biosimilar to be interchangeable and why is that important?

143

FAQ: What resources do you use to understand the latest approaches to managing IBS-C patients?

144

FAQ: What are some best practices in determining clinically meaningful “response” to therapy for IBS-C patients?

145

GHAPPcast: Biosimilars and the Patient Perspective

146

GHAPPcast: Mastering IBS-C: Diagnostic Strategies, Differentiation, and Management.

147

FAQ: What is the Difference Between Biosimilars and Generics?

148

FAQ: What Role Does a New Mechanism of Action Play in Your Prescribing Decisions of IBS-C Therapy?

149

GHAPPcast: Biosimilars Unveiled: Empowering APPs for Better Patient Conversations

150

CLDF/GHAPP Roundtable Podcast Series: MASH with Nadege Gunn, MD, Elizabeth Goacher, PA, and Ann Moore, FNP

151

Discussing Biosimilars With Patients

152

The Nocebo Effect

153

The Practical Use of Biosimilars in Gastroenterology APP Practice

154

The Practical Use of Biosimilars in Rheumatology APP Practice

155

The Benefits of Biosimilars

156

Managed Care and Biosimilars

157

Interchangeability & Switching of Biosimilars

158

Biosimilar Extrapolation

159

The Difference Between Biosimilars & Generic Drugs

160

The Regulatory Pathway to Biosimilar Approval

161

Development of Biosimilars

162

Biosimilars Series: What Are Biosimilars?