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All Episodes

RhAPPcast — 209 episodes

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Title
1

Journal Club Review: Deucravacitinib in Active PsA: 52-Week Efficacy and Safety From POETYK PsA-2

2

RhAPPcast: Cracking the Code: A Rheum Derm Neuro Multispecialty Case Approach to Myositis

3

RhAPPcast: Beyond the Joint: Uncontrolled Gout as a Systemic Disease

4

Journal Club Review: TOGETHER-PsA Trial

5

FAQ: How Do Clinical Manifestations and Histopathologic Features Vary Across Myositis Subtypes?

6

FAQ: What Are the Key Unmet Needs in the Treatment of Idiopathic Inflammatory Myopathies?

7

RhAPPcast: Switch, Don’t Cycle: Interpreting the SELECT-SWITCH Trial and What It Means for RA Care

8

RhAPPcast: Treat-to-Target in SLE: DORIS Remission Real in Practice

9

RhAPPcast: Pharmacists in Rheumatology

10

RhAPPcast: EULAR Osteoporosis RhAPP Up: Part 3

11

RhAPPcast: EULAR Osteoporosis RhAPP Up: Part 2

12

RhAPPcast: EULAR Osteoporosis RhAPP Up: Part 1

13

RhAPPcast: EULAR PsA RhAPP Up: Part 3

14

RhAPPcast: EULAR PsA RhAPP Up: Part 2

15

RhAPPcast: EULAR PsA RhAPP UP: Part 1

16

RhAPPcast: EULAR ILD RhAPP Up: Part 3

17

RhAPPcast: EULAR ILD RhAPP Up: Part 2

18

RhAPPcast: EULAR ILD RhAPP UP: Part 1

19

RhAPPcast: TYK2 Inhibition in PsA, Sjögren’s and SLE: What APPs Need to Know as Future Uses Emerge

20

Journal Club Review: SURMOUNT-5

21

Medication Review: Deucravacitinib Dosing, Administration, DDIs, & Safety in Clinical Practice

22

Podcast: Weight, Wellness, and PsA: Empowering Conversations & Action in the Rheumatology Clinic

23

FAQ: TYK2/STAT Signaling: The Immunologic Rationale for TYK2 Therapy in SLE & Sjögren’s Disease

24

RhAPPcast: From Prescription to Possession: Understanding Medicare Access & Cap and Smooth

25

FAQ: What Is Minimal Disease Activity in PsA and How Does Deucravacitinib Perform at 52 Weeks?

26

FAQ: What Guideline Recommendations Exist Pertaining to Managing obesity in Patients With PsA?

27

RhAPPcast: Identification and Diagnosis of XLH: A Story of Family History

28

Medication Review: What Is the Safety Profile of Tirzepatide?

29

Medication Review: Tirzepatide Starting Dose & Titration for Optimal Outcomes

30

Journal Club Review: SOLSTICE Publication

31

FAQ: How Can HPP Be Misdiagnosed in Rheumatology and What Are Common Diagnostic Pitfalls?

32

Medication Review: Describe The Mechanism of Action of Tirzepatide

33

Journal Club Review: APEX Publication

34

RhAPPcast: Diagnostic Crossroads: Clues, Pitfalls, and the Journey to an HPP Diagnosis

35

Journal Club Review: The Challenge of Hypophosphatasia Diagnosis in Adults

36

FAQ: How Does Weight Reduction Impact PsA Outcomes?

37

FAQ: What Are the Neuromuscular and Functional Burdens of Living With HPP?

38

RhAPPcast: IVIG Unpacked

39

Journal Club Review: DISCOVER-2 Severe PsA Publication

40

FAQ: How Does Obesity Affect PsA Outcomes?

41

FAQ: What Skeletal and Dental Manifestations Might Indicate HPP?

42

RhAPPcast: SubQ Solutions: Induction and Maintenance in Moderately to Severely Active CD and UC

43

RhAPPcast: Upadacitinib in GCA: Interpreting the 2-Year SELECT-GCA Results

44

FAQ: What is the Importance of MRI in Assessing Axial Disease Manifestations in PsA?

45

FAQ: How Does Obesity Impact the Immune System?

46

FAQ: What Role Does Power Doppler Ultrasound Play in Detecting Subclinical Inflammation/Enthesitis?

47

RhAPPcast: Unpacking the Genetics: Low ALP

48

FAQ: What Is the Efficacy of Switching MOA to Guselkumab After Inadequate Response to a single TNFi?

49

Podcast: Inflammation Intersection: A Rheum-Gi Dialogue

50

RhAPPcast: Protecting Joints: Inhibiting Structural Damage in PsA With Guselkumab

51

FAQ: How Can Clinicians Best Approach Talking to Patients With PsA About Weight Management?

52

Med Review: What is the Safety and Efficacy Profile of Guselkumab in Juvenile Psoriatic Arthritis?

53

Medication Review: Anti-Drug Antibody Development With Guselkumab in Psoriasis, PsA & IBD

54

FAQ: What Role Does Tissue-Nonspecific Alkaline Phosphatase (TNSALP) Play in HPP?

55

Medication Review: Laboratory Monitoring for Guselkumab in Psoriasis, PsA, and IBD

56

Podcast: Inflammation Amplified: Understanding the PsA—Obesity Connection

57

Medication Review: Safety and Efficacy of Guselkumab in Crohn’s Disease and Ulcerative Colitis

58

Across The Rheum Podcast: Part 3 - Clinical Utility and Positioning of IL-23 Agents

59

Podcast: Under the Surface: Exploring the HPP Diagnosis in Adulthood

60

FAQ: Screening Tools APPs Use to Identify PsA, SpA, or IBD and Refer Early

61

FAQ: What Validated Screening Tools Identify PsA/SpA or IBD for Rheumatology or GI Referral?

62

Across The Rheum Podcast: Part 2 - Currently Available IL-23 Agents

63

Journal Club: HPP Diagnosis—Current State of the Art & Proposed Criteria for Children and Adults

64

Med Review: What is the Safety and Efficacy Profile of Guselkumab in Juvenile Psoriatic Arthritis?

65

Across The Rheum Podcast: Part 1: Immunology of IL-23

66

RhAPPcast: Born with Burden: Understanding the Pediatric Presentation of HPP

67

RhAPPcast: Unpacking the Differences: IL-23 Inhibitors in Focus

68

FAQ: What is Hypophosphatasia and How Does It Present Across the Lifespan?

69

Journal Club: Guselkumab Binds To CD64+ IL-23–Producing Myeloid Cells to Neutralize IL-23 Signals

70

FAQ: How Is Hypophosphatasia Diagnosed and What Are the Key Laboratory Markers?

71

What Is the Correlation of CD64 and IL-23 Expression in Inflamed Joint, Skin, and Gut Tissue?

72

FAQ: What is the Normal Role of CD64 in Innate and Adaptive Immunity?

73

Podcast: A Tale of Two Pediatric APPs

74

Medication Review: Describe the Dual Mechanism of Action of Guselkumab

75

FAQ: Why is the mvdH-S Score Used Most Often in PsA Trials?

76

FAQ: How Does The Design of APEX Differ From DISCOVER-2 To Enrich For Structural Damage?

77

The Conversation That Matters: Talking to Patients About Obesity and IMIDs

78

From Insight to Action: Practical Strategies to Improve Outcomes in Patients with Obesity and IMIDs

79

The Hidden Costs: Obesity’s Role in Suboptimal Outcomes and Healthcare Burden in IMIDs

80

Obesity and IMIDs: Unpacking the Epidemic and Its Far-Reaching Impacts

81

Live from RhAPP National: ILD & PH-ILD at the Rheum–Pulm Crossroads

82

RhAPPcast: ANCA-Associated Vasculitis: Insights From the RhAPP National Conference

83

FAQ: What is the clinical significance of structural damage in PsA?

84

Medication Review: Evidence for Guselkumab in Preventing Structural Damage Progression

85

RhAPPcast: Beyond Dryness: Key Takeaways from the Sjögren’s Symposium at RhAPP 2025

86

FAQ: What is the Effect of Guselkumab on Structural Damage in PsA?

87

FAQ: What is the Inflation Reduction Act & How Does It Impact Affordability of Biologic Therapies?

88

RhAPPcast: Unmasking XLH: Misdiagnosed and Misunderstood

89

RhAPPcast: Refractory PMR: When Steroids Aren’t Enough – Unmet Needs in Treatment

90

RhAPPcast: The Safety Conversation: Upadacitinib in the Treatment of GCA

91

Medication Review: What is the safety profile of sarilumab in PMR & RA?

92

RhAPPcast: Expanding the Arsenal: JAK Inhibitors in the Evolving GCA Landscape

93

Medication Review: How is Sarilumab Dosed & Administered for the Treatment of PMR & RA?

94

Medication Review: Key Patient Education When Starting Sarilumab for PMR or RA

95

RhAPPcast: Inside the Evidence: A Deep Dive into the SELECT-GCA Study

96

RhAPPcast: Laying the Foundation: Historical Approaches to GCA Treatment

97

FAQ: What is the Role of Sarilumab in Managing PMR?

98

Journal Club: Comparative Effectiveness of Sarilumab vs. Methotrexate as a Corticosteroid-Sparing Agent in Patients with Polymyalgia Rheumatica

99

FAQ: Choosing Between Steroid-Sparing Agents in PMR Treatment

100

Medication Review: Leflunomide Medication Review

101

RhAPPcast: Spotting the Signs: Recognizing and Diagnosing Giant Cell Arteritis

102

RhAPPcast: Foundations of PMR: Diagnosis, First-Line Therapy, and Tapering Strategies

103

Journal Club Review: Sarilumab for Relapse of Polymyalgia Rheumatica During Glucocorticoid Taper

104

FAQ: Steroid-Sparing Agent Consideration in PMR Management & What Options Are Available?

105

FAQ: What Are the Most Recent Treatment Guidelines for PMR, and What Are the Key Clinical Takeaways?

106

Medication Review: What is the Mechanism of Action of Methotrexate?

107

Journal Club Review: A Review of the Safety and Efficacy of Deucravacitinib for Plaque Psoriasis

108

RhAPPcast: Understanding the TYK2/STAT Signaling Pathway in PsA: Clinical Implications and Beyond

109

Medication Review: Hydroxychloroquine Medication Review

110

FAQ: How Does the Selectivity of TYK2 and JAK Enzyme Inhibition Influence Their Safety Profiles

111

FAQ: According to the New 2024 ACR Guidelines for Lupus Nephritis, How Do You Monitor LN?

112

FAQ: Can You Recapture Response to IL-17i Therapy After Interruption or Discontinuation in Therapy?

113

FAQ: Steroid Tapering in Lupus Nephritis: Insights from the 2024 ACR Guidelines

114

Medication Review: What Is the Safety Profile of Deucravacitinib in PsO and PsA?

115

Journal Club Review: Voclosporin in Lupus Nephritis: New Insights on Efficacy & Safety from Clinical Trials

116

Medication Review: What is the Mechanism of Action of Deucravacitinib?

117

RhAPPcast: Practical Application: Integrating the New ACR LN Guidelines

118

Medication Review: What is the Real World Evidence of Guslekumab in PsA

119

FAQ: TYK2/STAT Pathway & Why TYK2 Therapy Works for Psoriasis and Psoriatic Arthritis

120

RhAPPcast: Decoding IL-17: Comparing and Contrasting IL-17A and IL-17F Inhibition

121

Medication Review: What Are the Clinically Meaningful Differences Between Voclosporin and Other Calcineurin Inhibitors?

122

RhAPPcast: ACR Psoriatic Arthritis RhAPPUp Part 3

123

RhAPPcast: ACR Psoriatic Arthritis RhAPPUp Part 2

124

RhAPPcast: ACR Psoriatic Arthritis RhAPPUP Part 1

125

RhAPPcast: The Relative Persistency and Effectiveness of Guselkumab in the Real-World

126

Medication Review: What is the safety profile of voclosporin and how should it be monitored?

127

Journal Club Review: Evaluating the Efficacy of Biologic With and Without Methotrexate

128

Journal Club Review: Voclosporin for Lupus Nephritis: Efficacy & Safety Insights from AURORA 1 & 2 Trials

129

Medication Review: Voclosporin Dosing, Administration, Adjustments & Interactions

130

Medication Review: What is the Efficacy of Guselkumab Across the GRAPPA Domains

131

FAQ: Are IL-17 Inhibitors Efficacious in Treating the Nail-DIP Complex in PsA?

132

FAQ: What Are CNIs? Treating Lupus Nephritis with the Latest ACR Guidelines

133

RhAPPcast: Elevating Care in LN: What the New ACR Guidelines Mean for Patients & How APPs can Apply Them

134

FAQ: How do IL-23 and IL-17 Inhibitors Differ in Clinical Efficacy

135

Journal Club Review: Ixekizumab vs. Guselkumab in Plaque Psoriasis (12-Week Trial Results)

136

Medication Review: What is Voclosporin and How Does it Work?

137

FAQ: According to the New 2024 ACR Guidelines for LN, What Are the Treatment Goals For Patients With LN?

138

Journal Club Review: Long-Term Safety of Guselkumab in Patients with Psoriatic Disease

139

RhAPPcast: Navigating Leflunomide Use in Pregnant Patients with Sjögren’s Syndrome

140

FAQ: According to the New 2024 ACR Guidelines, How Do You Treat LN?

141

FAQ: How Do You Interpret cDAPSA/DAPSA and MDA?

142

FAQ: How Do You Explain The Timing of Ixekizumab's Clinical Efficacy to Patients?

143

FAQ: 2024 ACR Guidelines: Screening & Diagnosing Lupus Nephritis in SLE Patients

144

RhAPPcast: LN Updates Unpacked: Insights on New ACR Guidelines

145

FAQ: How is Lupus Nephritis Defined?

146

FAQ: How Does Real-World Evidence Differ From Randomized Controlled Trials

147

FAQ: How Long Has It Been Since the Last ACR LN Guideline Updates, and Why Is This Significant?

148

Journal Club Review: Effectiveness of Methotrexate and Leflunomide as Corticoid-Sparing Drugs

149

RhAPPcast :The Clinical Utility of Guselkumab in Axial PsA

150

Journal Club Review: Efficacy & Safety of Ixekizumab ± Methotrexate in PsA (52-Week SPIRIT-H2H)

151

FAQ: How Do You Interpret Radiographic Progression Using Modified-vdHS or mTSS?

152

Medication Review: What Is the Efficacy of Ixekizumab Across the GRAPPA and EULAR Domains?

153

Medication Review: What Is the Safety Profile of Guselkumab in PsO and PsA?

154

FAQ: How Does Axial PsA Differ From AS Clinically, Genetically, and Radiographically?

155

Journal Club Review: 6-Month Guselkumab Effectiveness in PsA (Real-World CorEvitas Data)

156

RhAPPcast: Navigating the Complexities: IL-17 Inhibitors and IBD Risk

157

FAQ: Why is Binding CD64+ Important When Discussing IL23 Directed Therapy

158

Journal Club Review: Upadacitinib Safety & Efficacy in Pediatric JIA (Phase-1 Interim Data)

159

RhAPPcast: Lost Time: The Impact of Delaying Optimal Therapy in RA & SpA Patients Without Disease Control

160

Journal Club Review: 5-Year Data on Switching Upadacitinib & Adalimumab in RA

161

FAQ: Definition of Remission in Rheumatoid Arthritis & Likelihood with Advanced Therapies

162

Medication Review: How is Guselkumab dosed in PsO, PsA, and IBD

163

RhAPPcast: Navigating Remission in Rheumatoid Arthritis: Approaches, Advances, Impact, and Insights

164

FAQ: Variability in JAK Inhibition Specificity & Its Clinical Implications

165

RhAPPcast: CD64+ Binding Description, Relevance, and Potential Clinical Implications

166

FAQ: What Is the Difference Between Biosimilars and Generics?

167

FAQ: What Is the ORAL Surveillance Study and How Can It Be Applied to Clinical Practice?

168

FAQ: What is the Safety Profile of Ixekizumab in PsA and axSpa

169

Medication Review: What Is the Safety Profile of Upadacitinib Across Indications?

170

FAQ: Provide Immunologic Rationale For IL23 Directed Therapy in PsA, PsO, and IBD.

171

RhAPPcast: Biosimilars and The Patient Perspective

172

Medication Review: How Is Upadacitinib Dosed Across Rheumatologic Indications?

173

FAQ: Provide Immunologic Rationale for JAK-Directed Therapy in Rheumatic Disease

174

Medication Review: Describe the Mechanism of Action of Upadacitinib

175

FAQ: Provide Immunologic Rationale For IL17-Directed Therapy in PsA, AS, and nr-axSpA

176

FAQ: Describe the IL17-Induced Inflammatory Cascade

177

FAQ: Describe JAK-STAT Signaling in Inflammation

178

FAQ: What Does It Mean for a Biosimilar to Be Interchangeable and Why Is That Important?

179

Journal Club Review: Long-Term Efficacy and Safety of Guselkumab

180

Medication Review: What is Non-Responder Imputation and How is it Utilized in Clinical Trials

181

RhAPPcast: Biosimilars Unveiled - Empowering APPs for Better Patient Conversations

182

Medication Review: Describe The Mechanism of Action of Ixekizumab

183

FAQ: What is The Role of IL23/IL17 Axis in Rheumatic Disease

184

RhAPPcast: The IL23/IL17 Cascade and Implications in the Pathogenesis of PsA, PsO, and IBD

185

The 2024 RhAPP National Conference in Nashville, TN

186

FAQ: Describe The IL23/IL17 Axis

187

Journal Club Review: Differentiation of Therapeutic Antibodies Targeting Interleukin (IL)-23

188

Medication Review: Describing the Mechanism of Action of Guselkumab

189

FAQ: Define, compare, and contrast humoral and cell-mediated immunity.

190

RhAPPcast Spotlight: Clinical Cornerstones with Lindsay Tom, PA-C

191

RhAPPcast Spotlight: Clinical Cornerstones with Cayla Alexander, DNP, ARNP

192

Breathing New Life: HRCT and PFTs in ILD with Corinne Young of APAPP

193

Spotlight: Clinical Cornerstones, Mary Elliott, PA-C

194

Leading the Way: Dr. John Cush on Rheumatology Leadership

195

Discussing Biosimilars With Patients

196

The Nocebo Effect

197

Voices for Change: Madelaine Feldman, MD of CSRO on Advocacy in Rheumatology

198

The Practical Use of Biosimilars in Gastroenterology APP Practice

199

The Practical Use of Biosimilars in Rheumatology APP Practice

200

The Benefits of Biosimilars

201

Managed Care and Biosimilars

202

Interchangeability & Switching of Biosimilars

203

Spotlight: Clinical Cornerstones, Daric Mueller, MS, PA-C

204

Biosimilar Extrapolation

205

The Difference Between Biosimilars & Generic Drugs

206

The Regulatory Pathway to Biosimilar Approval

207

Development of Biosimilars

208

From Idea to Impact: The RhAPP Origin Story

209

Biosimilars Series: What Are Biosimilars?