Y Combinator Startup Podcast cover art

All Episodes

Y Combinator Startup Podcast — 316 episodes

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Title
1

"The CEO Must Be the Chief AI Officer"

2

How to Build an AI-Native Services Company

3

How To Build Superintelligence Inside Your Company

4

How The Best Companies Defend Against Mediocrity And Rot

5

Paul Graham: Should you move to Silicon Valley?

6

Tokenmaxxing: How Top Builders Use AI To Do The Work Of 400 Engineers

7

Beyond Bigger Models: Recursion As The Next Scaling Law In AI

8

How to Build the Future: Demis Hassabis

9

The $9B Startup That Wants to Create a Billion New Developers

10

The Playbook For Building An AI Native Company

11

Stripe Head of Design Katie Dill Breaks Down Their New Website

12

The GPT Moment for Robotics Is Here

13

This Startup Wants To Catch Cancer Before It Spreads

14

This Startup Secretly Detects Fraud For Fortune 500s

15

How François Chollet Is Building A New Path To AGI

16

Inside The Startup Reinventing America’s Trillion Dollar Chemical Industry

17

Building A Global AI Startup From India

18

The Future Of Brain-Computer Interfaces with Science's Max Hodak

19

How To Avoid AI Design Slop

20

The Fastest Path To Super Intelligence

21

The AI Agent Economy Is Here

22

Inside Claude Code With Its Creator Boris Cherny

23

The New Way To Build A Startup

24

OpenClaw And The Future Of Personal AI Agents

25

We're All Addicted To Claude Code

26

How To Get Your First Customers

27

Inside The Startup Building Reusable Rockets

28

What Surprised Us Most In 2025

29

How Intelligent Is AI, Really?

30

The End of the Designer–Engineer Divide

31

From Pivot Hell To $1.4 Billion Unicorn

32

The Best Consumer Startup Ideas Were "Impossible" Until Now

33

Cursor Head of Design Reviews Startup Websites

34

Inside The Startup Launching AI Into Space

35

How To Recruit The Best Engineers And Sales Reps

36

From Idea to $650M Exit: Lessons in Building AI Startups

37

Transformers: The Discovery That Sparked the AI Revolution

38

YC Partners Answer Your Questions | Office Hours

39

What Everyone Is Getting Wrong About AI And Jobs

40

How To Design Products That Truly Stand Out

41

The World's First Commercial Mobile Carbon Capture Device

42

Every AI Founder Should Be Asking These Questions

43

Anthropic Head of Pretraining on Scaling Laws, Compute, and the Future of AI

44

Fintech 3.0: Now Is The Best Time To Build In Crypto

45

Aaron Levie: Why Startups Win In The AI Era

46

The Future of Software Creation with Replit CEO Amjad Masad

47

The FDE Playbook for AI Startups with Bob McGrew

48

Michael Truell: Building Cursor at 23, Taking on GitHub Copilot, and Advice to Engineering Students

49

GPT-OSS vs. Qwen vs. Deepseek: Comparing Open Source LLM Architectures

50

How This 25-Year-Old Built A $675M Legal AI Startup (With No Legal Experience)

51

The Sales Playbook for Founders | Startup School

52

Figma CEO Dylan Field: How AI Will Transform Design

53

The Finance Startup Bringing Agentic AI to Wall Street

54

Scaling and the Road to Human-Level AI | Anthropic Co-founder Jared Kaplan

55

Brand Design Tips From Linear Founder Karri Saarinen

56

Chelsea Finn: Building Robots That Can Do Anything

57

Replit CEO Amjad Masad: Coding Agents, Autonomy, and the Future of Work

58

John Jumper: AlphaFold and the Future of Science

59

Aravind Srinivas: The Race to Build the AI Browser of the Future

60

Andrew Ng: Building Faster with AI

61

François Chollet: The ARC Prize & How We Get to AGI

62

Fei-Fei Li: Spatial Intelligence is the Next Frontier in AI

63

Legendary Consumer VC Predicts The Future Of AI Products

64

Satya Nadella: Microsoft's AI Bets, Hyperscaling, Quantum Computing Breakthroughs

65

Sam Altman: The Future of OpenAI, ChatGPT's Origins, and Building AI Hardware

66

Elon Musk: Digital Superintelligence, Multiplanetary Life, How to Be Useful

67

Andrej Karpathy: Software Is Changing (Again)

68

Cursor CEO: Going Beyond Code, Superintelligent AI Agents And Why Taste Still Matters

69

Fusion Energy Is Tech's Next Big Unlock

70

AI Apps Are Broken — Here's How To Fix Them

71

How AI Coding Agents Will Change Your Job

72

How To Get The Most Out Of Vibe Coding | Startup School

73

How Zepto Became India’s Fastest Growing Startup

74

Why America Stopped Innovating - And How We Can Start Again

75

What Founders Can Do To Improve Their Design Game

76

How to Build the Future: Tony Xu

77

Customer Obsession Made Gusto A $9.6 Billion Company

78

The Future Of Design With Figma's Dylan Field

79

How To Build The Future: Aravind Srinivas

80

Building A Supersonic Plane Company From The Ground Up

81

The Right (And Wrong) Way To Spend Money At Your Startup

82

How To Build The AGI Future: Bob McGrew

83

How To Use AI In Your Startup

84

How To Build The Future: Parker Conrad

85

Building A $2 Billion SaaS Company: Lessons From A Two Time Founder

86

How David Lieb Turned A Failed Startup Into Google Photos | Backstory

87

How To Start A Dev Tools Company with Nicolas Dessaigne | Startup School

88

Twitter vs. X: Product Lessons For Startup Founders | The Breakdown

89

How To Build The Future: Sam Altman

90

How Do Billion Dollar Startups Start? | Office Hours

91

Why Design Matters: Lessons from Stripe, Lyft and Airbnb | Design Review

92

How To Find A Co-Founder with Harj Taggar | Startup School

93

How To Convert Customers With Cold Emails with Aaron Epstein | Startup School

94

How To Improve Cohort Retention with David Lieb | Startup School

95

Co-Founder Equity Mistakes to Avoid with Michael Seibel | Startup School

96

How Nothing Founder Carl Pei Built A Multi-Million Dollar Smartphone Brand In Just 2 Years | Main Function

97

How To Price For B2B with Tom Blomfield | Startup School

98

Why Startup Founders Should Launch Companies Sooner Than They Think | Office Hours

99

Enterprise Sales with Pete Koomen | Startup School

100

Startup Experts Discuss Doing Things That Don't Scale | Office Hours

101

How to Survive the Crypto Boom & Bust Cycle | Main Function

102

Consumer Startup Metrics with Tom Blomfield | Startup School

103

When Should You Trust Your Gut? | Dalton & Michael Podcast

104

Building Confidence In Yourself and Your Ideas | Dalton & Michael Podcast

105

Stop Innovating (On The Wrong Things) | Dalton & Michael Podcast

106

Should Your Startup Bootstrap or Raise Venture Capital? | Dalton & Michael Podcast

107

How To Build A Tech Startup With No Technical Skills | Dalton & Michael Podcast

108

B2B Startup Metrics with Tom Blomfield | Startup School

109

Should You Be Optimistic About The Future of Technology? | Dalton & Michael Podcast

110

AI and the Future of Law: The 10 Year "Overnight" Success Story | Main Function

111

How To NOT Get Screwed As A Software Engineer | Dalton & Michael Podcast

112

Should You Quit Your Job At A Unicorn? | Dalton & Michael Podcast

113

Does Your Startup Need To Be In San Francisco?

114

Will OpenAI Kill All Startups?

115

Silicon Valley's Cargo Culting Problem

116

Setting KPIs and Goals with Divya Bhat | Startup School

117

Tips For Technical Startup Founders | Startup School

118

Secrets You Can Learn From Your Customers

119

The Student's Guide To Becoming A Successful Startup Founder

120

Inside The Most Powerful Startup Community In The World

121

How Startup Fundraising Works with Brad Flora | Startup School

122

How to Build An MVP with Michael Seibel | Startup School

123

How To Earn Customers For Life

124

The REAL Potential of Generative AI

125

The Hard Conversations Founders Don't Want to Have

126

The Best Way To Launch Your Startup with Kat Mañalac | Startup School

127

Advantages Of A First-Time Founder

128

The Cult of Conformity in Silicon Valley

129

Don't Make These Hiring Mistakes

130

Keys To Successful Co-Founder Relationships with Cat Li & Divya Bhat | Startup School

131

How To Compete With Amazon and Google

132

The Secrets To Setting Smarter Goals

133

Investors Said No, Now What?

134

When to Launch Your Startup and When to Wait

135

How to Get Your First Customers with Gustaf Alströmer | Startup School

136

Startup Business Models and Pricing with Aaron Epstein | Startup School

137

How to Talk to Users with Gustaf Alströmer | Startup School

138

How to Get and Evaluate Startup Ideas with Jared Friedman | Startup School

139

Should You Start a Startup? with Harj Taggar | Startup School

140

Avoid These Tempting Startup Ideas

141

The Truth About Y Combinator

142

The Two Mindsets That Can Kill Your Startup

143

What Basic Game Theory Teaches Us About Startups

144

Most Important Lifestyle Habits Of Successful Founders

145

Elon Musk & The Midwit Meme

146

Things That Don't Scale, The Software Edition

147

Why Investors (including YC) Can’t Fix Your Company

148

What Does It REALLY Mean To Do Things That Don't Scale?

149

How To Change The World? Get The Small Things Right

150

Simple Products That Became Big Companies

151

Where Do Great Startup Ideas Come From?

152

Successful Founders Are OK With Rejection

153

Should You Follow Your Passion?

154

Understanding Investor Terms & Incentives

155

YC Founders Made These Fundraising Mistakes

156

YC Founder Firesides: Gusto on building for new verticals

157

Co-Founder Mistakes That Kill Companies & How To Avoid Them

158

Dealing With Setbacks And The Startup Gut Punch

159

Saving Your Startup During an Economic Downturn

160

Why You Should Leave Your FAANG Job

161

How Future Billionaires Get Sh*t Done

162

#157 - Diego Saez Gil

163

#156 - Amber Atherton and Iba Masood

164

#155 - Laks Srini

165

#154 - Matt Cutts

166

#153 - Cory Doctorow and Joe Betts-LaCroix

167

#151 - Startup School Week 10 Recap - Ali Rowghani on How to Lead and Kevin Hale and Adora Cheung on Startup School 2019 by the Numbers

168

#150 - Startup School Week 9 Recap - Carolynn Levy on Modern Startup Financing and Jared Friedman’s Advice for Hard-tech and Biotech Founders

169

#149 - Startup School Week 8 Recap - Adora Cheung on Prioritizing Your Time and Kevin Hale on Evaluating Startup Ideas

170

#148 - Startup School Week 7 Recap - Kevin Hale on Conversion Rates and Pricing

171

#147 - Startup School Week 6 Recap - Tim Brady on Culture and Dalton Caldwell on Pivoting

172

#146 - Startup School Week 5 Recap - Kirsty Nathoo and Kevin Hale

173

#145 - Startup School Week 4 Recap - Kat Mañalac and Gustaf Alströmer

174

#144 - Startup School Week 3 Recap - Anu Hariharan and Adora Cheung

175

#143 - Startup School Week 2 Recap: Michael Seibel, Adora Cheung, and Ilya Volodarsky

176

#142 - Startup School Week 1 Recap: Kevin Hale and Eric Migicovsky

177

#141 - Diana Hu

178

#140 - Aaron Harris on Fundraising and Meeting with Investors

179

#139 - Jay Reno

180

#138 - Russ Roberts

181

#137 - Startup School Podcast Preview with Kevin Hale

182

#136 - Anu Hariharan on Managing a Board

183

#135 - Camille Fournier

184

#134 - Sarah Nahm and Holly Liu

185

#133 - Updates for Startup School 2019 and Office Hours with Kevin Hale

186

#132 - Dan Hockenmaier and Gustaf Alströmer

187

#131 - Jeremy Rossmann

188

#130 - Tracy Young and Kat Manalac

189

#129 - Simone Giertz

190

#128 - Michael Babineau and Kevin Hale

191

#127 - Vidit Aatrey and Adora Cheung

192

#126 - Chris Best and Jonathan Gill

193

#125 - Brian Halligan and Kevin Hale

194

#124 - Jarvis Johnson

195

#123 - Harry Zhang and Kevin Hale

196

#122 - Max Rhodes and Anu Hariharan

197

#120 - Austen Allred

198

#119 - Amy Buechler and Michael Seibel

199

#118 - Marques Brownlee

200

#117 - Craig Cannon and Adora Cheung

201

#116 - Domonique Fines and Cadran Cowansage

202

#115 - Mike Knoop and Kevin Hale

203

#114 - Karn Saroya

204

#113 - Caterina Fake and Kat Manalac

205

#112 - Ryan Hoover and Dalton Caldwell

206

#111 - Jake Klamka and Kevin Hale

207

#110 - Avni Patel Thompson and Kat Manalac

208

#109 - Samantha Bradshaw

209

#108 - Cindy Mi and Qi Lu

210

#107 - Vinod Khosla and Sam Altman

211

#106 - Frank Lantz

212

#105 - Reham Fagiri and Kalam Dennis

213

#104 - Leonard Susskind

214

#103 - Michael Seibel

215

#102 - Andrew Kortina

216

#101 - Brian Donohue

217

#100 - Sam Altman

218

#99 - Laura Deming

219

#98 - Shola Akinlade

220

#97 - David Hua and Vincent Ning

221

#96 - Mathilde Collin

222

#95 - Eli Schwartz

223

#94 - Joan Lasenby

224

#93 - Peter Reinhardt

225

#92 - Ryan Petersen

226

#91 - David Zeevi

227

#90 - Jessica Brillhart

228

#89 - Geoff Ralston and Adora Cheung Discuss Startup School

229

#88 - Office Hours with Michael Seibel

230

#87 - Elad Gil

231

#86 - Jocko Willink and Mike Sarraille

232

#85 - YC Partner AMA at the Female Founders Conference

233

#84 - João Batalha and Luís Batalha

234

#83 - Scott Aaronson

235

#82 - Henrique Dubugras of Brex and Anu Hariharan

236

#81 - Announcing Work at a Startup

237

#80 - Office Hours with Adora Cheung

238

#79 - Liz Wessel

239

#78 - Simon Benjamin

240

#77 - John Preskill

241

#76 - Carola Schönlieb

242

#75 - Sean Mitchell

243

#74 - Linda Xie and Avichal Garg

244

#73 - Patrick Moberg and Holly Liu

245

#72 - Miles Brundage and Tim Hwang

246

#71 - Claire McDonnell and Jennifer Kim on Building an Inclusive Company Culture

247

#70 - CoinList Cofounder Andy Bromberg and Ramon Recuero

248

#69 - Anne Wojcicki of 23andMe and Sam Altman

249

#68 - Cost vs Quality in Edtech - Keith Schacht, Avichal Garg, and Geoff Ralston

250

#67 - 3D Home Printing for the Developing World - Alexandria Lafci and Brett Hagler of New Story Charity

251

#66 - Breaking Down HackerRank's Survey of 40,000 Developers with Vivek Ravisankar

252

#65 - Funding Is an Outcome of Building a Good Business - Porter Braswell of Jopwell

253

#64 - Researching Psilocybin's Effects on Depression - Dr. Rosalind Watts

254

#63 - The Number One Goal is Getting Started - Avni Patel Thompson of Poppy

255

#62 - Dan Lewis, CEO of Convoy, on the Future of Freight

256

#61 - Sam Altman on Masters of Scale

257

#60 - Startup Investor School Preview with Geoff Ralston

258

#59 - Providing Fair Financial Products for the 56% of the US Without Access to Them - Jake Rosenberg of LendUp

259

#58 - It's Surprising How Much Small Teams Can Get Done - Sam Chaudhary of ClassDojo

260

#57 - Alex Blumberg of Gimlet Media

261

#56 - Leah Culver of Breaker and Tom Sparks of YC Answer Your Questions About Security and Podcasting

262

#55 - Tim Urban of Wait But Why

263

#54 - Growth Office Hours: Round 2

264

#53 - Be Wary of Solving a Small, Rare Problem - Des Traynor of Intercom

265

#52 - Making Physical Retail as Easy as Opening an Online Store - Ali Kriegsman and Alana Branston of Bulletin

266

#51 - There's an Art to Getting Brilliant People to Surprise Themselves - Kevin Slavin of The Shed

267

#50 - Growth Office Hours with Anu Hariharan and Gustaf Alstromer

268

#49 - Microbes, Robots, and Ambition - Robin Sloan on His Novel Sourdough

269

#48 - The Future of Bike Sharing with Ofo Cofounder Yanqi Zhang and Anu Hariharan

270

#47 - Baidu's COO, Qi Lu Discusses AI with Daniel Gross

271

#46 - Tencent's Chief eXploration Officer, David Wallerstein on WeChat, QQ, and Gaming

272

#45 - Building Dota Bots That Beat Pros - OpenAI's Greg Brockman, Szymon Sidor, and Sam Altman

273

#44 - Cindy Mi on Building VIPKID, the World's Largest English Learning Platform for Children

274

#43 - Casey Neistat and Matt Hackett on Live Video's Struggle for Interestingness

275

#42 - Robotics and 3D Printing with Voodoo Manufacturing

276

#41 - Experiments in Art and Technology with Artforum Editor Michelle Kuo

277

#40 - Content Marketing Tips from Experts at First Round Capital and Andreessen Horowitz

278

#39 - Mr. Robot's Technical Producer and Writer - Kor Adana

279

#38 - The More You Communicate with Users, the Higher Chance You'll Build Something They Want - Ryan Hoover of Product Hunt

280

#37 - Don't Start a Blog, Start a Cult - Mr. Money Mustache

281

#36 - Your Whole Goal Is to Not Quit - Courtland Allen of Indie Hackers

282

#35 - The Technical Challenges of Measuring Gravitational Waves - Rana Adhikari of LIGO

283

#34 - Elizabeth Iorns on Biotech Companies in YC

284

#33 - The Challenges a Repeat Founder Faces

285

#32 - Hosain Rahman on The "Defibrillator Experiences" of Jawbone

286

#31 - Spotting Ecommerce Trends in Shipping Data – Laura Behrens Wu

287

#30 - Artist Lauren McCarthy Will Be Your Home's Brain

288

#29 - Jack Dorsey On The Books That Helped Him Succeed

289

#28 - Prerequisites for Starting a Company - Phil Libin

290

#27 - The CEO Who Pays Employees to De-Locate From the Bay

291

#26 - Founders of Science Exchange, Goldbely, and The Flex Company Discuss Fundraising

292

#25 - Baidu's AI Lab Director on Advancing Speech Recognition and Simulation

293

#24 - Padmasree Warrior on Designing Autonomous Vehicles - With Anu Hariharan at the Female Founders Conference

294

#23 - VMware Cofounder Diane Greene with Jessica Livingston at the Female Founders Conference

295

#22 - Morgan DeBaun on Reaching 20M Millennials - With Kat Manalac at the Female Founders Conference

296

#21 - Emily Weiss on the Insights That Grew Glossier - With Amy Buechler at the Female Founders Conference

297

#20 - Making Music and Art Through Machine Learning - Doug Eck of Magenta

298

#19 - Blockchain Investing - Olaf Carlson-Wee and Aaron Harris

299

#18 - Q&A with YC Partners at the Female Founders Conference

300

#17 - Aileen Lee and Kirsty Nathoo at the Female Founders Conference

301

#16 - Mark Zuckerberg on How to Build the Future

302

#15 - IPFS, CoinList, and the Filecoin ICO - Juan Benet and Dalton Caldwell

303

#14 - Ex Machina's Scientific Advisor - Murray Shanahan

304

#13 - Scaling Growth - Gustaf Alstromer, Ed Baker, and Josh Elman

305

#12 - How Should Business Schools Prepare Students for Startups? - Jeff Bussgang and Michael Seibel

306

#11 - At The Intersection of AI, Governments, and Google - Tim Hwang

307

#10 - Office Hours with Ali Rowghani

308

#9 - Sam Altman and Reid Hoffman - From Startup to Scaleup

309

#8 - Rick and Morty Writer - Ryan Ridley

310

#7 - Jessica Livingston on How to Build the Future

311

#6 - Office Hours with Kat Manalac

312

#5 - An AI Primer with Wojciech Zaremba

313

#4 - Elon Musk on How to Build the Future

314

#3 - The Technical Advisor for Silicon Valley on HBO - Ed McManus

315

#2 - Network Effects with Anu Hariharan

316

#1 - Hiring Engineers with Ammon Bartram