Decoding Healthcare Research

In this episode, we delve into the intricacies of habit formation and the crucial role of integrating knowledge into daily practice. Our distinguished guest, Professor Bas Verplanken, shares his expertise on developing new habits. Professor Verplanken is the Faculty Director of Doctoral Studies at the University of Bath's Faculty of Humanities & Social Sciences. His research encompasses areas such as behavioral and mental habits, attitude-behavior relations, health behaviors, and environmental behavior. Join us as we explore practical strategies for habit creation and discuss how to effectively implement them in our everyday lives. Timelapse 00:00 Introduction 01:17 The motivation behind the research 05:50 What is a habit, and how is it created? 12:25 Why do we create habits? 15:02 The transition to a new habit 20:01 How motivations behind a habit can change 24:45 The value system shaping habits 30:12 How to sustain habits 39:40 The role of external motivation Follow me on social media: Instagram:   / doctoref.rain   Facebook:   / efrain.riverosperez   Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we dive into the fascinating world of the microbiome and gut permeability with our guest, Dr. Maria Fernanda Roca, PhD. Dr. Roca previously conducted research at Örebro University in Sweden and now works at the prestigious Karolinska Institute. Her work focuses on the intricate connections between immunity and gut health. Join us as we uncover how stress can influence these vital systems. We hope you enjoy the discussion! References: -Roca Rubio MF, Eriksson U, Brummer RJ, König J. Sauna dehydration as a new physiological challenge model for intestinal barrier function. Sci Rep. 2021 Jul 30;11(1):15514. doi: 10.1038/s41598-021-94814-0. PMID: 34330970; PMCID: PMC8324874. -Roca Rubio MF, Eriksson U, Brummer RJ, König J. Short intense psychological stress induced by skydiving does not impair intestinal barrier function. PLoS One. 2021 Jul 8;16(7):e0254280. doi: 10.1371/journal.pone.0254280. PMID: 34237102; PMCID: PMC8266057. Follow me on social media:  Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure:  The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the effects of alcohol on exercise and muscle performance. Learn how alcohol impacts protein production, the mTOR pathway, and overall athletic performance. Our guest, Dr. Jakob Vingren, shares insights from his extensive research in kinesiology. Dr. Vingren holds a Ph.D. from the University of Connecticut and focuses on resistance exercise and the hormonal and muscular effects of alcohol. Reference: Levitt DE, Idemudia NO, Cregar CM, Duplanty AA, Hill DW, Vingren JL. Alcohol After Resistance Exercise Does Not Affect Muscle Power Recovery. J Strength Cond Res. 2020 Jul;34(7):1938-1944. doi: 10.1519/JSC.0000000000002455. PMID: 29385007. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the fascinating connection between stress and wound healing. Dr. Elizabeth Broadbent, a researcher at the University of Auckland in New Zealand, joins us to discuss how stress can hinder the healing process and the critical role inflammation plays. Dr. Broadbent, who holds an MSc and PhD in Health Psychology, delves into relaxation techniques that can promote better healing outcomes. Her expertise in Health Psychology, Psychoneuroimmunology, and Human-Robot Interaction offers unique insights into the mind-body connection. References: Broadbent E, Petrie KJ, Alley PG, Booth RJ. Psychological stress impairs early wound repair following surgery. Psychosom Med. 2003 Sep-Oct;65(5):865-9. doi: 10.1097/01.psy.0000088589.92699.30. PMID: 14508033. Broadbent E, Kahokehr A, Booth RJ, Thomas J, Windsor JA, Buchanan CM, Wheeler BR, Sammour T, Hill AG. A brief relaxation intervention reduces stress and improves surgical wound healing response: a randomised trial. Brain Behav Immun. 2012 Feb;26(2):212-7. doi: 10.1016/j.bbi.2011.06.014. Epub 2011 Jun 28. PMID: 21741471. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we discuss the role of Vitamin D in diabetes and metabolic syndrome. Our guest is Dr. Izabela Szymczak-Pajor, PhD, a researcher at the Medical University of Łódź | UMED, in the Department of Nucleic Acid Biochemistry. We experienced some technical difficulties during the recording and apologize in advance for the audio issues in certain parts of the podcast. However, we didn’t want to miss the opportunity to share this valuable discussion. We hope you enjoy the episode! References: -Szymczak-Pajor I, Drzewoski J, Śliwińska A. The Molecular Mechanisms by Which Vitamin D Prevents Insulin Resistance and Associated Disorders. Int J Mol Sci. 2020 Sep 11;21(18):6644. doi: 10.3390/ijms21186644. PMID: 32932777; PMCID: PMC7554927. -Szymczak-Pajor I, Śliwińska A. Analysis of Association between Vitamin D Deficiency and Insulin Resistance. Nutrients. 2019 Apr 6;11(4):794. doi: 10.3390/nu11040794. PMID: 30959886; PMCID: PMC6520736. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we discuss the genetic aspects of diabetes. Our guest, Dr. Beenish Masood, completed her medical education in Internal Medicine at Dow University of Health Sciences, Pakistan, and her Master's in Clinical Endocrinology at Queen Mary University of London. She has worked as a Research Clinical Fellow in Diabetes at Barts Health NHS Trust and as a Clinical Teaching Fellow in Diabetes and Endocrinology at The Royal Free Hospital in London, UK. Her research focuses on metabolic disorders, including diabetes. Reference: Masood B, Moorthy M. Causes of obesity: a review. Clin Med (Lond). 2023 Jul;23(4):284-291. doi: 10.7861/clinmed.2023-0168. PMID: 37524429; PMCID: PMC10541056. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we talk about the effects of alcohol on the brain, sleep, and circadian rhythm. This time, the conversation will be based on an animal model. Our guest, Dr. Anthony Lange, Ph.D., a Postdoctoral Research Scholar in Neuroscience & Pharmacology at the University of Iowa, will enlighten us about his research, which mainly focuses on the neural mechanisms underlying social behaviors. Enjoy! Reference: Lange AP, Wolf FW. Alcohol sensitivity and tolerance encoding in sleep regulatory circadian neurons in Drosophila. Addict Biol. 2023 Aug;28(8):e13304. doi: 10.1111/adb.13304. PMID: 37500483; PMCID: PMC10911855. Disclosure:  The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the fascinating role of epigenetics in sleep and sleep disorders. Our guest, Dr. Rene Cortese, a researcher in the Departments of Pediatrics and Obstetrics and Gynecology at the University of Missouri School of Medicine, brings his expertise in epigenetics and complex diseases to the discussion. Dr. Cortese’s research focuses on how complex diseases develop, progress, and are inherited, with a special emphasis on identifying potential treatments. His current work examines epigenetic mechanisms in genome regulation, especially those affecting children's and women's health. Hope you find this episode insightful! Reference: Cortese R. Epigenetics of Sleep Disorders: An Emerging Field in Diagnosis and Therapeutics. Diagnostics (Basel). 2021 May 10;11(5):851. doi: 10.3390/diagnostics11050851. PMID: 34068472; PMCID: PMC8150507. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we’re diving into the ketogenic diet in the context of bodybuilding and muscle preservation. Our guest, Dr. Antonio Paoli, Professor of Exercise and Sport Sciences at the Department of Biomedical Sciences, University of Padova, and Chair of Strength Training and Sport Nutrition at UCAM University in Murcia, Spain, will shed light on this compelling topic. Dr. Paoli's research focuses on the ketogenic diet, fasting, and the interaction between exercise and diet on skeletal muscle metabolism. He also explores the molecular foundations of exercise adaptation and the effects of various resistance training methods on health and body composition in both young and adult populations. Reference: Paoli A, Cenci L, Pompei P, Sahin N, Bianco A, Neri M, Caprio M, Moro T. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders. Nutrients. 2021 Jan 26;13(2):374. doi: 10.3390/nu13020374. PMID: 33530512; PMCID: PMC7911670. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the fascinating role of fructose in our metabolism and how it might influence obesity through the “survival switch hypothesis.” Our guest, Dr. Richard Johnson from the Anschutz School of Medicine at the University of Colorado, joins us to discuss his insights on how fructose could be triggering significant changes in metabolism. Together, we dive into how these changes are implicated in obesity, insulin resistance, and other metabolic diseases. Join us for an enlightening conversation that could reshape the way we understand the impacts of fructose on health. Hope you enjoy the episode! Reference: Johnson RJ, Lanaspa MA, Sanchez-Lozada LG, Tolan D, Nakagawa T, Ishimoto T, Andres-Hernando A, Rodriguez-Iturbe B, Stenvinkel P. The fructose survival hypothesis for obesity. Philos Trans R Soc Lond B Biol Sci. 2023 Sep 11;378(1885):20220230. doi: 10.1098/rstb.2022.0230. Epub 2023 Jul 24. PMID: 37482773; PMCID: PMC10363705. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

Reference: Koob GF. Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement. Biol Psychiatry. 2020 Jan 1;87(1):44-53. doi: 10.1016/j.biopsych.2019.05.023. Epub 2019 Jun 12. PMID: 31400808. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we dive into a critical topic: how are we supporting each other globally to produce and publish research? Our guest, Emmanuel Ameh, Professor of Pediatric Surgery at the National Hospital in Abuja, Nigeria, shares valuable insights into the challenges faced in Africa when it comes to research and publication, challenges that are also experienced in Latin America. He discusses the initiatives and collaborations that have been developed to address these issues and improve the research landscape. This conversation is an eye-opener for anyone interested in the global research community. We hope you find it inspiring and insightful! References: -Krakauer KN, Wong LY, Tobias J, Majekodunmi O, Balumuka D, Bravo K, Ameh E, Finlayson S, Nwomeh B, Sifri Z, Charles A, Krishnaswami S; SUS Committee on Academic Global Surgery. Evaluating Global Surgery Partnerships From Low and Middle Income Country Perspectives. J Surg Res. 2024 Apr;296:681-688. doi: 10.1016/j.jss.2024.01.040. Epub 2024 Feb 15. PMID: 38364695. -Peters AW, Roa L, Rwamasirabo E, Ameh E, Ulisubisya MM, Samad L, Makasa EM, Meara JG. National Surgical, Obstetric, and Anesthesia Plans Supporting the Vision of Universal Health Coverage. Glob Health Sci Pract. 2020 Mar 31;8(1):1-9. doi: 10.9745/GHSP-D-19-00314. PMID: 32234839; PMCID: PMC7108944. Follow me on social media:  Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure:  The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore one of the most exciting advancements in c4ncer care: liquid biopsy. How is this innovative technique transforming c4ncer detection and treatment? Dr. Christian Rolfo, MD, PhD, recently appointed as the Director of the Division of Medical Oncology at The Ohio State University Comprehensive Cancer Center, shares his expertise on this game-changing technology. Dr. Rolfo discusses how liquid biopsy is advancing precision medicine, detecting c4ncer biomarkers, and shaping the future of oncology. Tune in to learn how this breakthrough could be the next big leap in c4ncer treatment! Dr. Rolfo specializes in drug development, lung c4ncer, and thoracic malignancies, with a strong focus on biomarkers and resistance mechanisms. He has also been a Professor with tenure in the Division of Hematology and Medical Oncology, and a Professor at the Institute for Translational Epidemiology in Cancer, both at the Icahn School of Medicine, Mount Sinai Health System, New York. He has also served as the Associate Director of Clinical Research for the Center of Excellence for Thoracic Oncology at the Tisch Cancer Institute. Reference: Rolfo C, Malapelle U, Russo A. Expanding the Full Potential of Liquid Biopsies for Lung Cancer Patients. Cancer Res. 2022 Aug 16;82(16):2826-2828. doi: 10.1158/0008-5472.CAN-22-2109. PMID: 35971678. Visit the International Society of Liquid Biopsy website: https://islb.info/ Upcoming events: 6th Annual Congress of Liquid Biopsy: "Advancing and Accelerating Access of Liquid Biopsy” (ISLB 2024) in Denver, Colorado, USA. November 23-25, 2024. More info: https://2024.islb.info/ Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we are joined by Nori Geary, a distinguished researcher and former Professor in the Department of Psychiatry at Weill Cornell Medical College, who conducted extensive studies in physiology, metabolism, body weight, and more. Now retired, Dr. Geary shares his expertise as we explore control-theory models of body-weight regulation and the crucial role of appetite in maintaining body weight. Enjoy this insightful discussion on the science behind appetite and body-weight regulation! Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Geary N. Control-theory models of body-weight regulation and body-weight-regulatory appetite. Appetite. 2020 Jan 1;144:104440. doi: 10.1016/j.appet.2019.104440. Epub 2019 Sep 5. PMID: 31494154. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we will discuss the various mechanisms that have been researched in relation to the browning of adipose tissue. Our guest, an expert in the field, Dr. Guillermo Sanchez, PhD, who works at the University of Sherbrooke and the University of Granada, Spain, will shed light on this fascinating topic that is helping us, day by day, to better understand crucial information that could be used to preserve our metabolic health. Reference: Mendez-Gutierrez A, Osuna-Prieto FJ, Aguilera CM, Ruiz JR, Sanchez-Delgado G. Endocrine Mechanisms Connecting Exercise to Brown Adipose Tissue Metabolism: A Human Perspective. Curr Diab Rep. 2020 Jul 28;20(9):40. doi: 10.1007/s11892-020-01319-7. PMID: 32725289. Disclosure:  El contenido de este podcast es puramente académico y está destinado únicamente con fines educativos e informativos. Los temas discutidos no representan ni reflejan las opiniones, perspectivas o políticas del Medical College of Georgia, y la información presentada no debe interpretarse como asesoramiento médico o guía. Siempre consulte con un profesional de la salud calificado para cualquier preocupación o pregunta médica. Quiero dejar claro que no cuento con el respaldo, afiliaciones o intereses financieros en compañías farmacéuticas o fabricantes de dispositivos médicos. Cualquier mención de medicamentos, dispositivos o tratamientos se realiza únicamente en el contexto de la literatura y la discusión académica.

In this episode, we will discuss how what we eat can profoundly affect our metabolism and health, down to the molecular and genetic levels. Specifically, we will explore how nutrition impacts us at the epigenetic level. Our guest, Dr. Carsten Carlberg, will shed light on this topic. Dr. Carlberg is the ERA Chair for Nutrigenomics at the Polish Academy of Sciences in Poland and a Professor of Biochemistry at UEF. His research has focused on vitamin D for over 30 years, studying its effects on changes in the epigenome. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Carlberg C, Velleuer E. Nutrition and epigenetic programming. Curr Opin Clin Nutr Metab Care. 2023 May 1;26(3):259-265. doi: 10.1097/MCO.0000000000000900. Epub 2022 Dec 23. PMID: 36728887. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we discuss the role of vitamin C and its importance for our health. Our guest for this interview is Dr. Eck, an Associate Professor in the Department of Food and Human Nutritional Sciences at the University of Manitoba. His research focuses on genetics, nutrition, and their relationship with various diseases and metabolism. This conversation was based on the following article: Granger M, Eck P. Dietary Vitamin C in Human Health. Adv Food Nutr Res. 2018;83:281-310. doi: 10.1016/bs.afnr.2017.11.006. Epub 2018 Feb 16. PMID: 29477224 Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the crucial role sleep plays in our metabolic health with Dr. Kanagasabai, who shares insights from her groundbreaking research on the subject. From insulin resistance and diabetes to inflammation and oxidative stress, discover how sleep impacts these vital health markers. Dr. Kanagasabai, who completed her PhD in Health Science at York University, has worked as a Visiting Assistant Professor at St. Lawrence University in the US, and is currently a Postdoctoral Fellow in Environmental Epidemiology at McGill University, brings her extensive knowledge on sleep patterns, circadian rhythms, and cardiometabolic health outcomes to the discussion. Don’t miss this in-depth look at how sleep can influence your overall health. Reference: Kanagasabai T, Riddell MC, Ardern CI. Inflammation, Oxidative Stress, and Antioxidant Micronutrients as Mediators of the Relationship Between Sleep, Insulin Sensitivity, and Glycosylated Hemoglobin. Front Public Health. 2022 Jun 9;10:888331. doi: 10.3389/fpubh.2022.888331. PMID: 35757614; PMCID: PMC9218604. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the fascinating world of aging and the intricate processes that drive it. We'll discuss how various types of stress impact our bodies, influence the aging process, and affect longevity. Joining us is Dr. Marios Kyriazis, a seasoned gerontologist, researcher, and Director of the National Gerontology Centre in Cyprus, working in collaboration with the Ministry of Health. Tune in to gain valuable insights into how aging works and what it means for our future. Enjoy! Reference: Kyriazis M, Swas L, Orlova T. The Impact of Hormesis, Neuronal Stress Response, and Reproduction, upon Clinical Aging: A Narrative Review. J Clin Med. 2023 Aug 21;12(16):5433. doi: 10.3390/jcm12165433. PMID: 37629475; PMCID: PMC10455615. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we will discuss the important role of nutrition in our immunity and health, how what we eat influences our response to disease, and what we can do to improve our defenses. Our guest today is Dr. Philip Calder, BSc(Hons), PhD, DPhil, RNutr, FRSB, FAfN. He is the Head of Human Development & Health and Professor of Nutritional Immunology at Southampton University in England. His research focuses on the nutritional modulation of immunity, inflammation, and cardiometabolic disease risk. Much of his work has been devoted to exploring the metabolism and functionality of fatty acids, with an emphasis on the roles of omega-3 fatty acids. Dr. Calder has over 700 scientific publications and is listed as a Highly Cited Researcher. He has also received several awards in related fields. Enjoy! Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Calder PC. Nutrition and immunity: lessons for COVID-19. Eur J Clin Nutr. 2021 Sep;75(9):1309-1318. doi: 10.1038/s41430-021-00949-8. Epub 2021 Jun 23. PMID: 34163017; PMCID: PMC8220366. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we discuss aging as a natural process that everyone experiences, emphasizing that it doesn't necessarily have to be detrimental. On the contrary, by understanding the factors behind it, we can make decisions to positively influence this process. Our guest, Tamas Fulop, MD, PhD, is a professor of medicine and geriatrics and a senior researcher at the Research Center on Aging, University of Sherbrooke, Québec, Canada. Reference: Fulop T, Larbi A, Pawelec G, Khalil A, Cohen AA, Hirokawa K, Witkowski JM, Franceschi C. Immunology of Aging: the Birth of Inflammaging. Clin Rev Allergy Immunol. 2023 Apr;64(2):109-122. doi: 10.1007/s12016-021-08899-6. Epub 2021 Sep 18. PMID: 34536213; PMCID: PMC8449217. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we are going to analyze the effect of sleeping at regular times on our long-term health. I hope this information is useful to you. I invite you to leave your questions, opinions, and suggestions in the comments, and to share so that we can all continue learning together. -Instagram: https://www.instagram.com/dr.ef.rain/ -TikTok: https://www.tiktok.com/@dr.efrain -Facebook: https://www.facebook.com/efrain.riverosperez Reference: Windred DP, Burns AC, Lane JM, Saxena R, Rutter MK, Cain SW, Phillips AJK. Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study. Sleep. 2024 Jan 11;47(1) . doi: 10.1093/sleep/zsad253. PMID: 37738616; PMCID: PMC10782501. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we have two very special guests who are going to shed light on a developing field: the genotyping and analysis of circulating DNA in the detection and follow-up of cancer. This is part of the technologies in precision medicine that could contribute to improving the effectiveness of treatments. We are joined by Dr. Lilian Siu, a senior medical oncologist at the Princess Margaret Cancer Centre since 1998, and a Professor of Medicine at the University of Toronto since 2009. She is the Director of the Phase I Program and Co-Director of the Bras and Family Drug Development Program at the Princess Margaret Cancer Centre, and holds the BMO Chair in Precision Genomics (2016-2026). Dr. Siu’s major research focus is in the area of new anticancer drug development, particularly with respect to phase I trials and head and neck malignancies. Our other guest, Dr. David Cescon, is a breast medical oncologist and clinician-scientist at the Princess Margaret Cancer Centre. His research integrates laboratory and clinical studies, focused on identifying breast cancer therapeutic vulnerabilities and determinants of drug response and resistance. Leveraging pre-clinical model platforms and genomic tools, including liquid biopsy, the overarching goal of his work is to advance the delivery of precision therapy to improve breast cancer outcomes through both the prevention and treatment of metastatic disease. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Cescon DW, Bratman SV, Chan SM, Siu LL. Circulating tumor DNA and liquid biopsy in oncology. Nat Cancer. 2020 Mar;1(3):276-290. doi: 10.1038/s43018-020-0043-5. Epub 2020 Mar 20. PMID: 35122035. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we analyze the results of a study that evaluated the effects of consuming different doses of apple cider vinegar on the weight of adolescents and adults. I hope this information is useful to you. Follow me on social media:  Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Abou-Khalil R, Andary J, El-Hayek E. Apple cider vinegar for weight management in Lebanese adolescents and young adults with overweight and obesity: a randomised, double-blind, placebo-controlled study. BMJ Nutr Prev Health. 2024 Mar 12;7(1):61-67. doi: 10.1136/bmjnph-2023-000823. PMID: 38966098; PMCID: PMC11221284. Disclosure:  The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we have Dr. Dudley Lamming, PhD, Associate Professor and Researcher at the Department of Medicine, Endocrinology at the University of Wisconsin-Madison. We will talk about aging and specifically about a molecule that has been gaining interest in the scientific field: mTOR. We’ll discuss its importance, how it is regulated, and much more. Additionally, we will explore the effects of Rapamycin and its potential pharmacological applications. Join us for an insightful discussion! Dr. Lamming’s research focuses on understanding how nutrient-responsive signaling pathways can be harnessed to promote health and longevity. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Mannick JB, Lamming DW. Targeting the biology of aging with mTOR inhibitors. Nat Aging. 2023 Jun;3(6):642-660. doi: 10.1038/s43587-023-00416-y. Epub 2023 May 4. PMID: 37142830; PMCID: PMC10330278. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we analyze the results of a study that aimed to evaluate the impact of sleep quality on weight and energy balance in overweight individuals. I hope you find this information useful. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Tasali E, Wroblewski K, Kahn E, Kilkus J, Schoeller DA. Effect of Sleep Extension on Objectively Assessed Energy Intake Among Adults With Overweight in Real-life Settings: A Randomized Clinical Trial. JAMA Intern Med. 2022 Apr 1;182(4):365-374. doi: 10.1001/jamainternmed.2021.8098. PMID: 35129580; PMCID: PMC8822469. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we will talk about glucotypes, sugar, glycemia, and the impact of your body's capacity to properly respond to the sugar you eat in order to maintain a well-functioning metabolism. Our guest, Dr. Snyder, Chair of the Department of Genetics and Director of the Center for Genomics and Personalized Medicine at Stanford University, will shed light on the topic. I hope you enjoy the episode and find it useful. In the study we used as a base for the conversation, they explain how interindividual variability in glycemic responses to standardized meals highlights the personal nature of glucose regulation. Through extensive phenotyping, we developed a model for identifying potential metabolic differences. Reference: Hall H, Perelman D, Breschi A, Limcaoco P, Kellogg R, McLaughlin T, Snyder M. Glucotypes reveal new patterns of glucose dysregulation. PLoS Biol. 2018 Jul 24;16(7):e2005143. doi: 10.1371/journal.pbio.2005143. PMID: 30040822; PMCID: PMC6057684. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we analyze the results of a study that focused on determining whether the time of day when exercise is performed affects sleep quality or the ability to fall asleep. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: -Goldberg M, Pairot de Fontenay B, Blache Y, Debarnot U. Effects of morning and evening physical exercise on subjective and objective sleep quality: an ecological study. J Sleep Res. 2024 Feb;33(1):e13996. doi: 10.1111/jsr.13996. Epub 2023 Jul 10. PMID: 37431176. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we discuss the results of a paper that analyzes the health characteristics of people who live longer and healthier lives. Our guests, Dr. Karin Modig, PhD, and Dr. Shunsuke Murata, researchers at the Karolinska Institute in Sweden, explain their findings. Dr. Modig's main research focuses on comprehensively elucidating the determinants of increased longevity and assessing the quality of extended lifespan. Dr. Murata's research focuses on the prevention and management of disease and disability in older adults. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Murata S, Ebeling M, Meyer AC, Schmidt-Mende K, Hammar N, Modig K. Blood biomarker profiles and exceptional longevity: comparison of centenarians and non-centenarians in a 35-year follow-up of the Swedish AMORIS cohort. Geroscience. 2024 Apr;46(2):1693-1702. doi: 10.1007/s11357-023-00936-w. Epub 2023 Sep 19. Erratum in: Geroscience. 2024 Apr;46(2):2793-2794. doi: 10.1007/s11357-023-00996-y. PMID: 37726432; PMCID: PMC10828184. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

In this flash episode, we analyze the results of a study that evaluated the impact of sleep hours on our health markers. I hope this information is useful to you. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Addo PNO, Mundagowa PT, Zhao L, Kanyangarara M, Brown MJ, Liu J. Associations between sleep duration, sleep disturbance and cardiovascular disease biomarkers among adults in the United States. BMC Public Health. 2024 Apr 2;24(1):947. doi: 10.1186/s12889-024-18381-5. PMID: 38566084; PMCID: PMC10985959. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we discuss the impact of the microbiome on aging. Today's guest is Dr. Filipe Gomes Cabreiro, Professor at the University of Cologne-CECAD and Imperial College London. We talk about the importance of the microbiome and its involvement in many processes within our body. We cover changes in metabolism, DNA, and much more as we age, and explore the possibility of developing markers to compare our biological age to our chronological age. I hope this information is useful for you and sheds light on the importance of taking care of your gut microbiome. Dr. Cabreiro holds a PhD in Biochemistry and is a principal investigator at CECAD's research lab, where his research team focuses on understanding the mechanistic role played by microbes and nutrition in aging and healthspan. Reference to the paper: Bana B, Cabreiro F. The Microbiome and Aging. Annu Rev Genet. 2019 Dec 3;53:239-261. doi: 10.1146/annurev-genet-112618-043650. Epub 2019 Sep 5. PMID: 31487470. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, I present the results of a study that analyzed the relationship between multivitamin consumption and life expectancy. I also discuss the importance of knowing how to choose which vitamins to take and at what stage of life. I hope this information is useful to you. Reference: Loftfield E, O'Connell CP, Abnet CC, Graubard BI, Liao LM, Beane Freeman LE, Hofmann JN, Freedman ND, Sinha R. Multivitamin Use and Mortality Risk in 3 Prospective US Cohorts. JAMA Netw Open. 2024 Jun 3;7(6):e2418729. doi: 10.1001/jamanetworkopen.2024.18729. PMID: 38922615; PMCID: PMC11208972. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this express episode, we talk about a study that showed how the consumption of eggs can have a protective effect against dementia and Alzheimer's disease. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Margara-Escudero HJ, Zamora-Ros R, de Villasante I, Crous-Bou M, Chirlaque MD, Amiano P, Mar J, Barricarte A, Ardanaz E, Huerta JM. Association Between Egg Consumption and Dementia Risk in the EPIC-Spain Dementia Cohort. Front Nutr. 2022 Feb 23;9:827307. doi: 10.3389/fnut.2022.827307. PMID: 35284440; PMCID: PMC8906465. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we will discuss the role of exercise in transformation, specifically the browning of adipose tissue. Our guest, Dr. Milena Shonke, PhD, a researcher at Leiden University in the Netherlands, will talk to us about metabolism and the results of her research. Dr. Shonke's research focuses on the role of lipoprotein metabolism in the effect of exercise, and its timing in relation to the circadian rhythm, on the development of cardiovascular diseases. Her aim is to further unravel the crosstalk between metabolically relevant tissues like skeletal muscle, different types of adipose tissue, and the liver, modulating whole-body metabolic homeostasis. I hope you enjoy the episode. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we have a special guest with us, Dr. Gupta from Northwestern University, who is here to discuss food allergies in adults. She will cover the prevalence, symptoms, and manifestations, what to be especially aware of for your safety, medication prescriptions, and at the end, give some advice for physicians and patients. The objective is to help you potentially get a diagnosis so that you can receive appropriate treatment and improve your quality of life. Dr. Gupta is a Professor of Pediatrics and Medicine at Northwestern University Feinberg School of Medicine and a Clinical Attending at Ann & Robert H. Lurie Children’s Hospital of Chicago. She has 19 years of experience as a board-certified pediatrician and health researcher and currently serves as the founding director of the Center for Food Allergy & Asthma Research (CFAAR). Dr. Gupta is world-renowned for her groundbreaking research in the areas of food allergy and asthma epidemiology, most notably for her research on the prevalence of pediatric and adult food allergy in the United States. Along with being the author of "The Food Allergy Experience" and "Food Without Fear," Dr. Gupta has over 200 publications, and her work has been featured on major TV networks and in print media. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, Schleimer RP, Nadeau KC. Prevalence and Severity of Food Allergies Among US Adults. JAMA Netw Open. 2019 Jan 4;2(1):e185630. doi: 10.1001/jamanetworkopen.2018.5630. PMID: 30646188; PMCID: PMC6324316. Disclosure:  The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this express episode, we present the results of a study that analyzed the characteristics of people who live over 100 years. We present the findings regarding blood markers indicative of inflammation status and metabolic health. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Murata S, Ebeling M, Meyer AC, Schmidt-Mende K, Hammar N, Modig K. Blood biomarker profiles and exceptional longevity: comparison of centenarians and non-centenarians in a 35-year follow-up of the Swedish AMORIS cohort. Geroscience. 2024 Apr;46(2):1693-1702. doi: 10.1007/s11357-023-00936-w. Epub 2023 Sep 19. Erratum in: Geroscience. 2024 Apr;46(2):2793-2794. doi: 10.1007/s11357-023-00996-y. PMID: 37726432; PMCID: PMC10828184. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

In this episode, we have a special guest, Dr. Peter Mancuso, PhD, MS. We will discuss how excess fat in different compartments of the body can impact local and systemic inflammation, chronic disease, and ultimately aging. We will also explore the role of different adipokines and the immune system in this process. Dr. Mancuso is an Associate Professor of Nutritional Sciences and a faculty member of the Graduate Program in Immunology at the University of Michigan. His research focuses on the impact of obesity and diabetes on pulmonary infections and systemic inflammation in chronic disease. I hope you enjoy the episode and that it sheds light on an issue that affects all of us, raising awareness of our responsibility to take care of our bodies. Reference: Mancuso P, Bouchard B. The Impact of Aging on Adipose Function and Adipokine Synthesis. Front Endocrinol (Lausanne). 2019 Mar 11;10:137. doi: 10.3389/fendo.2019.00137. PMID: 30915034; PMCID: PMC6421296. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

On this occasion, I present the conclusions of an article from this year that studied the possible effects of fructose contained in sugary drinks on hormones and metabolism. It could be related to signs associated with hyperandrogenism, such as hirsutism (beard) and acne. It may also play a role in polycystic ovary syndrome and fertility problems. Reference: Chen, Huadong & Buziau, Amée & Renteria, Miguel E & Simons, Pomme & Brouwers, Martijn. (2024). Fructose intake from sugar-sweetened beverages is associated with a greater risk of hyperandrogenism in women: UK Biobank cohort study. European journal of endocrinology. 190. 104-112. 10.1093/ejendo/lvae006. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

In this episode, we will discuss the best strategies for relieving back pain. Based on recent evidence, I will provide some exercise recommendations that can help prevent and alleviate acute or chronic back pain. I hope this is helpful to you. I invite you to leave your questions, opinions, and suggestions in the comments, and to share so that we can all continue learning together. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

In this express episode, we analyze the results of a study conducted by researchers at the Cleveland Clinic in the United States. They studied the impact of xylitol on the cardiovascular system. It appears to have prothrombotic properties, meaning it causes platelets to tend to aggregate and form clots. As always, I recommend carefully reading labels the next time you go to the supermarket. I invite you to leave your questions, opinions, and suggestions in the comments, and to share so that we can all continue learning together. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Witkowski M, Nemet I, Li XS, Wilcox J, Ferrell M, Alamri H, Gupta N, Wang Z, Tang WHW, Hazen SL. Xylitol is prothrombotic and associated with cardiovascular risk. Eur Heart J. 2024 Jun 6:ehae244. doi: 10.1093/eurheartj/ehae244. Epub ahead of print. PMID: 38842092. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

What and when should you eat to increase muscle mass? What are the most effective exercises for gaining muscle mass? How much protein should I consume to build muscle? What are amino acids for? What are BCAAs for? Are they useful? Should I take supplements? I answer these and other questions about gaining muscle mass in this video. I hope you find it useful and enjoy it. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Graphs presented: Dai, Z., Zheng, W. & Locasale, J.W. Amino acid variability, tradeoffs and optimality in human diet. Nat Commun 13, 6683 (2022). https://doi.org/10.1038/s41467-022-34486-0 Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion

In this episode we analyze the results of a study that tested the effectiveness of taking a hot bath before sleeping to improve sleep quality. For those who suffer from insomnia, try it and I hope it helps! Reference: Maeda T, Koga H, Nonaka T, Higuchi S. Effects of bathing-induced changes in body temperature on sleep. J Physiol Anthropol. 2023 Sep 8;42(1):20. doi: 10.1186/s40101-023-00337-0. PMID: 37684642; PMCID: PMC10486043. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we talk about diet, the food we eat, and how it directly affects the microbiome, metabolism, and health. Our guest, Inge Lindseth, a registered nutritionist from Oslo, sheds light on the factors that influence the health of our microbiome. He talks about the interaction between diet, microbiota, and host, and takes part in research projects related to food processing and its effects on the microbiota and host health. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Zinöcker MK, Lindseth IA. The Western Diet-Microbiome-Host Interaction and Its Role in Metabolic Disease. Nutrients. 2018 Mar 17;10(3):365. doi: 10.3390/nu10030365. PMID: 29562591; PMCID: PMC5872783. Disclosure:  The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

We analyzed the information from an article published this month which found that fish oil might increase the risk of atrial fibrillation and cardiovascular disease in healthy individuals. The good news is that it appears to have benefits for people who already suffer from cardiovascular disease. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Reference: Chen G, Qian Z(, Zhang J, et alRegular use of fish oil supplements and course of cardiovascular diseases: prospective cohort studyBMJ Medicine 2024;3:e000451. doi: 10.1136/bmjmed-2022-000451 Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we will delve into the evidence on the health effects of ultra-processed foods. We will learn what they are, why they appeared, and how to identify processed food as a tool for making informed and better choices the next time we go grocery shopping. I hope this information is useful and that it inspires you to make better choices to eat better in favor of your wellness and general health. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion. NOVA Classification and Image used on the video: https://ecuphysicians.ecu.edu/wp-content/pv-uploads/sites/78/2021/07/NOVA-Classification-Reference-Sheet.pdf

Join us in this enlightening episode as we explore the crucial connection between metabolic health and the preservation of brain function, with a special focus on preventing Alzheimer's disease and dementia. We'll delve into the pivotal roles of fructose and uric acid in this intricate relationship, shedding light on their detrimental effects when present in excessive amounts. We're thrilled to welcome esteemed guest Dr. David Perlmutter, a board-certified neurologist, Associate Professor at the Miami Miller School of Medicine, Fellow of the American College of Nutrition, and six-time New York Times best-selling author. Dr. Perlmutter brings his wealth of expertise to our conversation, offering invaluable insights into the intersection of metabolism and brain health. Our discussion transcends dietary considerations, exploring the profound impact of the modern American diet and the pivotal role of daily lifestyle choices in shaping cognitive outcomes. Discover how proactive measures taken as early as 30 years before symptoms manifest can significantly influence long-term brain health. Follow me on social media: Instagram: @doctoref.rain Facebook: Efrain Riveros-perez This conversation was based in the following article: Reference: Johnson RJ, Tolan DR, Bredesen D, Nagel M, Sánchez-Lozada LG, Fini M, Burtis S, Lanaspa MA, Perlmutter D. Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism? Am J Clin Nutr. 2023 Mar;117(3):455-466. doi: 10.1016/j.ajcnut.2023.01.002. Epub 2023 Jan 11. PMID: 36774227; PMCID: PMC10196606. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we dive deep into the realm of cholesterol, unveiling its connection to metabolism and the crucial role of insulin in its regulation. We tackle questions such as:Is dietary cholesterol associated with cardiovascular risk and cardiovascular disease? Can I lower my cholesterol and still eat cholesterol? Is dietary cholesterol healthy? What food has the most cholesterol in it? Discover how our dietary habits impact our metabolic health and influence cholesterol levels. Join us as we explore the intricate interplay between nutrition, metabolism, and overall well-being. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

Join us in this episode as we delve into the intriguing topic of fasting and the fasting mimicking diet, and their profound impact on healthy lifespan. Our esteemed guest, Dr. Valter Longo, PhD in biochemistry and the Edna M. Jones Professor of Gerontology and Biological Sciences at the University of Southern California – Leonard Davis School of Gerontology, Los Angeles, shares invaluable insights from his extensive research at one of the foremost centers for aging and age-related disease studies. Dr. Longo, also serving as the Director of the Longevity and Cancer Program at the IFOM Institute of Molecular Oncology in Milan, Italy, brings a wealth of knowledge to the table. Through this engaging discussion, we explore the mechanisms behind fasting's effects on longevity, the science of the fasting mimicking diet, and its potential implications for human health and disease prevention. This conversation was based on the following article: Reference: Longo VD, Panda S. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab. 2016 Jun 14;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. PMID: 27304506; PMCID: PMC5388543. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, Dr. Alan Sacerdote MD, an endocrinologist specializing in diabetes and metabolism, discusses the crucial role of Vitamin D in metabolic health. Discover how Vitamin D deficiency correlates with various metabolic conditions and learn practical strategies for supplementation and lifestyle adjustments. Tune in for expert insights into optimizing metabolic health with Vitamin D. Dr. Sacerdote occupied the position of Chief of the Endocrinology Division at NYC Health and Hospitals Woodhull, and served as a Professor at SUNY Downstate Medical Center and New York University School of Medicine, among others. This conversation was based on the following article: Reference: Sacerdote A, Dave P, Lokshin V, Bahtiyar G. Type 2 Diabetes Mellitus, Insulin Resistance, and Vitamin D. Curr Diab Rep. 2019 Sep 10;19(10):101. doi: 10.1007/s11892-019-1201-y. PMID: 31506836. Don't forget to subscribe and follow me on social media. You can find me on Instagram as @doctoref.rain and Facebook as Efrain Riveros-pérez. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

Discover how diet can be a game-changer in managing menopause symptoms like hot flashes in this special episode featuring Dr. Neal Barnard, MD, FACC. Join us as we delve into the transformative potential of a plant-based, specifically vegan, rich in soy in relieving or even eliminating hot flashes and other menopause symptoms. Dr. Barnard, an acclaimed Adjunct Professor of Medicine at George Washington University, , President of the Physicians Committee for Responsible Medicine, and a New York Times bestselling author of 20 books, shares evidence-based insights into how dietary interventions can empower women to navigate menopause with ease and vitality. Don't forget to subscribe and follow me on social media. You can find me on Instagram as @doctoref.rain and Facebook as Efrain Riveros-pérez. This episode was based on the following article: Reference: Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, Zhao X, Galandi S, Setchell KDR. A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial. Menopause. 2023 Jan 1;30(1):80-87. doi: 10.1097/GME.0000000000002080. Epub 2022 Oct 16. PMID: 36253903; PMCID: PMC9812421. Also available at: Spotify, Apple Podcasts and Amazon Music as Decoding Healthcare Research Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.