Siim Land Podcast

Taken from my appearance at the Detached Podcast: https://youtu.be/aEuKyVFT93Y?si=bRtuQei0w7xo2s9N

Get The New Science of Supplements book: https://amzn.to/4ebe2LwTimestamps:00:00 Intro00:30 Top evidence-based supplements29:55 Supplements with the worst evidence34:25 Supplements that need more research47:58 Conclusion100 Supplements Ranked Tierlist Worst to Best: https://youtu.be/W8DZbYyuDmAStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

This is a replay of Siim Land on Chris MM Health's YouTube channel: https://www.youtube.com/watch?v=vXpES7lty2Q Timestamps: 0:00 – Intro0:56 – Beating Bryan Johnson In Biomarkers4:00 – Longevity Escape Velocity Explained4:39 – Can Humans Live To 150+ Years?10:10 – Biological Age & Longevity World Cup12:34 – Biological Age Of 10 Years Old?!14:10 – Most Important Longevity Biomarkers16:35 – VO2 Max, Visceral Fat & Fitness19:28 – Pull-Ups, Strength & Longevity22:44 – Inflammation, hs-CRP & Aging24:12 – HbA1c, Insulin & Triglycerides31:01 – Body Fat, Exercise & Mortality Risk40:44 – SIIM LAND’s Diet & Whole Foods46:24 – Why Perfect Health Is Not Enough51:20 – Supplements: Glycine, Omega-3 & More

Dr. Michael Snyder is a genomicist, professor, and former chair of genetics at Stanford University School of Medicine. He is the Director of the Center for Genomics and Personalized Medicine at Stanford University and a pioneer in precision medicine and multi-omic profiling.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:26 Dr. Snyder’s paper that changes the way we look at aging05:46 Why aging accelerates after 44 and 6009:31 What’s good for young people might not be good for someone who’s old12:10 Metabolic changes that happen during aging15:57 How big of a role does genetics play in longevity21:57 What’s going to extend lifespan more: genetic engineering or lifestyle interventions27:37 What is Multi-omics31:10 Continuous glucose monitoring35:10 Different types of glucose spikers38:40 HRV tracking42:00 How collecting more data can predict your health risks47:48 Is tracking health preemptively bad52:25 What people should track about their health57:00 How the retina reflect systemic health risks59:45 Biological age clocksDr. Michael Snyder's lab website: https://med.stanford.edu/snyderlab/about.htmlStart rewinding your biological clock: https://www.siimland.co/course

Siim Land returns as the current leader of the Longevity World Cup, to break down supplements, biomarkers, VO2 max, inflammation, sleep, and the difference between building health versus simply maintaining it.Watch on YouTube: https://www.youtube.com/watch?v=ogy7l0nka-Y

Dr. Alexis Ortega is board-certified in longevity, regenerative and aesthetic medicine. He has a clinic Ad Astra in Barcelona, Spain.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:55 How to counteract age-related loss of facial harmony aside from just wrinkles12:30 Does growth hormone change the face18:10 Bon Charge sponsorship19:17 What's the minimum effective dose of at-home skincare — the three things that actually move the needle?21:28 Retinoids24:05 Skin barrier support27:00 Effect of sun exposure on extrinsic skin aging31:02 Best evidence-based sunscreen ingredients34:34 List of best sunscreen ingredients36:00 Worst sunscreen ingredients37:45 Daily sunscreen vs using the UV index as a guide39:43 Do people overuse skincare products42:33 Castor oil, beef tallow and egg yolks for skin49:08 Are natural sunscreens effective49:59 If someone had unlimited money today, what are the most promising rejuvenation interventions actually available?51:08 What diagnostics Alexis would do with an unlimited budget54:30 Rejuvenation therapies Alexis would do55:18 Alexis approach to peptides56:00 Intravenous senolytics56:20 NAD injections57:14 What you can do now to practically extend lifespan59:40 Intravenous exosomes01:00:25 Therapeutic plasma exchange01:03:06 Stem cell therapy01:05:30 Gene therapies01:07:48 What biomarkers matter most for predicting long-term healthAlexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

Dr. Kevin Perez is a computational biologist working at the cutting edge of aging science and drug discovery. His work focuses on aging research, drug repurposing, and integrating complex multi-omics data to better understand how we can extend healthspan.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:47 Kevin’s study about pharmaceuticals that are associated with reduced mortality10:17 Which class of drugs had reduced mortality13:07 Bon Charge sponsorship14:12 How Kevin researches longevity molecules16:37 Estrogen’s longevity effects17:37 How Kevin started researching dog aging25:32 Chemical reprogramming29:32 Kevin’s understanding of what causes aging34:52 Metformin vs SGLT2 inhibitors38:37 Erectile dysfunction drugs43:02 Over the counter supplements with longevity effects45:52 Biological age clocks50:02 What Kevin thinks is the best biomarker of aging54:32 Composite biological age vs combination of multiple markers59:32 Kevin’s new study plans01:02:52 What Kevin wishes he adopted soonerStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Join our LONGEVITY Community: https://www.skool.com/longevity-societyTimestamps:00:00 Intro00:37 Why Brad crowd funded a rapamycin trial03:22 What Brad’s rapamycin trial found12:57 Why rapamycin blunted the effects17:17 Rapamycin effects on grip strength19:57 Rapamycin and immune effects21:47 Effects on biomarkers25:22 Brad’s thoughts on rapamycin moving forward31:52 Metformin exercise effects32:52 Other medicines with longevity potential36:37 Medicines that move the needle the most for people45:17 Will Brad do another study48:27 Brad on GLP-1sDr Brad Stanfield is a family medicine doctor in New Zealand: https://www.youtube.com/@DrBradStanfieldBloodwork for longevity panel discussion: https://youtu.be/7QONBQCpRJ0 My 2026 longevity routine: https://youtu.be/OceysodInIoStart rewinding your biological clock: https://www.siimland.co/course

Dr. Greg Potter has a PhD from the University of Leeds in sleep, nutrition, and metabolism. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:45 Catchup02:05 Are circadian rhythms nature or nurture09:55 What’s ideal timing of sunlight exposure for circadian anchoring15:25 Bon Charge sponsorship 20:30 Does creatine increase DHEA or DHT levels25:50 Does creatine reduce sleep quality33:25 Greg’s new podcast36:15 Is more REM sleep better42:05 How to optimize REM sleep44:25 What % of different sleep cycles should we get (light, deep, REM)46:10 Is food processing good or bad52:45 Incline bed therapy55:20 Is it bad to use sleep herbs58:45 Does melatonin supplementation stop natural production01:01:15 What to do if you wake up at night and can’t fall back asleepGreg Potter YouTube Channel: https://www.youtube.com/@gregpotterphd

Dr. Andrew Hill has a PhD in Cognitive Neuroscience from UCLA and has extensive experience in the field of neurofeedback and QEEG. He founded the Peak Brain Institute. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:45 — Andrew's new book Gifted and Tortured04:47 — Diagnosis vs resource-based brain optimization06:20 — The 12 core brain phenotypes07:57 — The stabilizer and supervisor: executive and sleep control10:23 — CEO and lifeguard phenotypes: hyperfocus, anxiety, and stuck thoughts12:41 — Language and auditory processing phenotypes14:53 — Bon Charge sponsorship16:00 — Phenotypes exist on a spectrum17:03 — Brain speed, memory, aging, and sleep-related brain fog20:15 — Interventions: sleep, meditation, supplements, and neurofeedback21:46 — The most common phenotypes Andrew sees26:30 — Supplements, stimulants, and nootropics29:24 — Why Andrew prefers training the brain over relying on meds32:26 — How accurate is self-diagnosis?35:12 — Sleep trackers, self-awareness, and measuring how you feel36:11 — Peak performance and flow states41:19 — Using phenotype to train smarter and recover better42:34 — Siim’s brain scan begins44:40 — What the brain map shows: fatigue, hyperfocus, and executive traits48:57 — Siim’s speed and focus test results53:20 — Andrew’s own brain phenotype and ADHD story58:20 — Can focus be trained?01:03:18 — Main takeaway: understanding your brain creates agencyDr. Andrew Hill YouTube channel: https://www.youtube.com/@DrHillMy 2026 longevity routine: https://youtu.be/OceysodInIoStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Professor Kristen Hawkes is a pioneering anthropologist whose work helped bring the grandmother hypothesis to the spotlight of human evolution research. Through fieldwork and evolutionary theory, she argued that older women may have played a crucial role in shaping the human life course, not just by living longer, but by helping feed and support grandchildren. That idea helped reframe menopause, longevity, and family cooperation as possible drivers of what makes humans distinct and what explains our longer lifespans.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro01:05 How Kristen started to think about the paradox of grandmother longevity09:15 What accounts for variation in adult mortality across lifespan13:40 Difference in male and female longevity17:20 Why human babies are very dependent 20:05 Bon Charge sponsorship21:10 Dynamics of human social evolution and longevity23:05 How longer weening period in human babies contributes to our intelligence29:35 Weening and intelligence34:25 Evolutionary explanation for grandparents36:35 The contribtion of hunting success vs gathering to children size in Hadza47:05 Does the grandmother hypothesis make sense48:15 Role of DHA and seafood in human brain evolution51:35 Social hierarchy of grandparents in the Hadza56:01 Grandfathers01:08:35 Role of grandparents in the modern worldMy 2026 longevity routine: https://youtu.be/OceysodInIoStart rewinding your biological clock: https://www.siimland.co/course

Dr. Uri Alon is a physicist-turned-biologist, a professor at the Weizmann Institute, and one of the leading thinkers exploring how complex biological systems work. In this episode, we discuss his research on the effects of genetics, lifestyle, environment, and luck on human lifespan.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:55 How big of a role does genetics play in longevity06:25 How important is lifestyle vs genetics08:25 How big of a role does lifestyle play in longevity12:55 Why is lifestyle less impactful than genetics15:25 Bon Charge sponsorship16:30 Genes of people who live to 11018:55 Why lifestyle matters a lot if you have bad genes21:45 What leads to aging22:45 What’s the maximum human lifespan25:20 Why nobody has lived over 122 yet27:05 Strategies to extend lifespan beyond normal34:05 What made Uri interested in longevity as a physicist36:25 Recurring patterns in human longevity and aging38:40 Simplest analogie for aging49:15 Surprising role of luck in longevity54:55 How to practically extend your lifespan59:30 What Uri needs to discover next about agingDr Uri Alon Lab YouTube channel with Systems Aging courses: https://www.youtube.com/@alonlab9733/videosMy 2026 longevity routine: https://youtu.be/OceysodInIoStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:36 Lifestyle bracket06:50 Lifestyle bracket winners11:47 Join my online community18:46 Medicine / pharmaceutical bracket19:20 Medicine /pharmaceutical bracket winners22:32 Geroscience bracket33:13 Geroscience winners35:00 Biohacking bracket40:16 Biohacking bracket winners43:04 Final 8 winners46:32 Final 4 winners49:23 Final 2 winnersVote yourself for the Longevity Bracket: https://www.optispan.life/longevity-bracketMy 2026 longevity routine: https://youtu.be/OceysodInIoStart rewinding your biological clock: https://www.siimland.co/course

Professor Michael Crawford is a renowned scientist and Director of the Institue of Brain Chemistry and Human Nutrition in Imperial College London. He’s known for his research demonstrating the essential role of omega-3s specifically DHA in brain development and human evolution. He’s been pioneering this research since the 70s and he’s 95 years old himself.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro01:00 How Dr Crawford started researching DHA and omega-3s04:00 Relationship between DHA and brain structure across species07:00 How DHA drove the evolution of the human brain12:20 Did humans evolve because of hunting land animals or consuming seafood16:10 How a waxy fatty layer covering human babies makes us so different from other land animals 19:50 Bon Charge sponsorship20:50 How the early stages of human brain evolution might have looked like24:20 Why did DHA allow our brains to develop so well27:20 Declining IQ and brain health conditions31:00 Behavioral disorders and DHA34:05 Iodine and other nutrients for brain development36:55 Dr Crawford’s amazing cognition at the age of 9539:20 How much DHA would people need per day41:40 Is fish high in heavy metals46:40 Omega-3s from meat50:20 Plant-based omega-3s51:20 Bottleneck for cranial capacity for land animals54:55 Supplementing vs eating seafood56:20 Omega-6 vs omega-3s57:30 What needs to be done for fixing nutrition01:03:30 Can you catch up with lost brain development01:06:00 Are omega-3s easily oxidized01:07:35 Advice for young researchers01:10:05 Dr Crawford’s bookMy 2026 longevity routine: https://youtu.be/OceysodInIo100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Dr. Benjamin Blue is the Chief Executive Officer of Ora Biomedical, where he leads the company’s mission to develop therapies that target the biology of aging to prevent and treat disease. Dr. Blue holds a Ph.D. in Molecular Medicine and Mechanism of Disease (M3D) from the University of Washington School of Medicine and a B.S. in Biochemistry from the University of Oregon.Timestamps:00:00 Intro00:35 The Million Molecule Challenge to find the enxt longevity molecule05:15 How many molecules has Ora Biomedical tested06:45 Most remarkable results in life extension so far10:45 The process of finding life extension molecules16:05 What’s the maximum life extension seen17:15 Join our online community18:15 Common supplements seen to extend lifespan21:55 Disappointing molecules for life extension26:50 Aspects of health and longevity30:45 Investigating radiation in space and aging34:35 Likelihood of finding a molecule that extends lifespan by 200-300%41:05 How does it translate to humans48:25 Peptides effect on lifespan52:05 Bottleneck in the longevity science56:25 What compounds has Ben started taking himselfDr Ben Blue Twitter: https://x.com/benblueAKJoin our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/My 2026 longevity routine: https://youtu.be/OceysodInIoStart rewinding your biological clock: https://www.siimland.co/course

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:41 Experts framework for bloodwork03:41 What can bloodwork tell you about your health and what not18:21 Brad’s top 3 most useful biomarkers20:21 Matt’s top 3 most useful biomarkers21:11 Is testosterone testing worth it on the population level29:01 Michael’s top 3 most useful biomarkers31:46 Matt’s most misleading biomarker34:01 Brad’s most misleading biomarker34:41 Biological age tests37:22 Join my online community38:23 ApoB44:45 HDL cholesterol48:50 Is low LDL associated with increased mortality58:45 Blood sugar markers01:02:12 How important are glucose spikes01:12:12 How often should you take bloodtests01:15:35 Liver markers01:19:30 When you shouldn’t measure everything01:22:40 Galleri cancer blood test01:25:17 Cost of bloodworkMatt Kaeberlein PhD is a biogerontologist and professor at University of Washington: https://www.youtube.com/@UCSna7385c3Xg_4Too92NKMw Michael Lustgarten PhD is an exercise scientist and longevity researcher: https://www.youtube.com/@UCT1UMLpZ_CrQ_8I431K0b-g Dr Brad Stanfield is a family medicine doctor in New Zealand: https://www.youtube.com/@DrBradStanfieldMy 2026 longevity routine: https://youtu.be/OceysodInIo

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Zone 2 cardio01:20 Barbell back squat01:38 Pistol squats02:21 Split squats02:58 Deadlift03:26 Pullups04:40 Pushups05:44 Barbell row07:35 Dumbbell row07:42 Overhead press08:29 Dumbbell shoulder press09:01 HIIT09:35 Delt flies11:30 Incline bench press12:21 Decline bench press12:55 Dips13:14 Handstand pushups14:29 Bon Charge sponsorship15:31 Leg press16:36 Biceps curls17:05 Triceps extension17:19 Yoga17:45 Hamstring curls18:41 Knee extension19:00 Calf raises20:14 Hammer curls20:50 Wrist curls21:30 Farmer carries22:21 Trap shrugs22:41 Neck curls24:20 Good mornings25:41 Hanging knee raises26:11 Hanging leg raises26:58 Sprinting27:31 Deadhang28:18 Kettlebell swings28:59 Rope climb29:59 Front lever31:34 Planche33:05 Crunches34:00 Back extensions34:31 L-sit35:33 L-sit pullups36:40 Plyometrics37:11 Walking lunges37:46 Hip thrust38:28 Planking39:20 Cycling40:30 Soccer41:50 Basketball42:11 Volleyball42:50 Tennis43:19 Skating43:35 Skiing44:08 Mobility44:31 Gymnastics45:45 Hockey46:13 Weighted vest walking46:45 Track and field47:00 Golf48:00 Baseball48:35 Rowing48:50 Stair climber49:30 Jump rope49:51 Combat sports50:51 Stretching52:00 Burpees52:55 Box jumps53:30 Medicine ball53:58 Sled push / pull54:12 Sandbag54:55 Wood chopping56:10 Turkish get-up57:00 Muscle up57:40 Skin the cat58:39 Agility ladders59:28 Swimming59:55 Shadow boxing01:01:10 Animal flow01:01:55 Ab wheel rollout01:02:32 Front squat01:03:28 Stiff leg deadlift01:03:40 Chi ups01:04:08 Seal row01:05:00 Javelin throw01:05:30 Heavy throws01:06:28 Olympic weightlifting01:07:54 Walking01:08:18 Suitcase carry01:08:50 Bosu ball squat01:09:45 Assault bike01:10:10 Dancing01:10:47 Handstand01:11:15 Hiking01:11:45 ConclusionMy 2026 longevity routine: https://youtu.be/OceysodInIo100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro01:15 TB405:02 Thymosin alpha 109:44 Join our longevity community10:43 Epitalon15:26 MOTS-c19:30 Humanin21:32 Cerebrolysin23:49 Semax24:40 CJC1295 (Ipamorelin)26:31 MK677 (Ibutamoren)28:26 Tesamorelin29:12 IGF-1 LR329:45 Copper GHK32:22 Retatrutide33:55 Melanotan 235:30 Final overview and rankingMy 2026 longevity routine: https://youtu.be/OceysodInIo100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyiStart rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Top Health Factors and Biomarkers That Matter the Most17:44 Bon Charge sponsorship18:50 Glycine and cancer risk22:05 Can supplements improve IQ and cognition25:19 Best autophagy routines31:24 Thoughts on young plasma exchange35:26 Injectible NAD and glutathione38:05 Too high cortisol from time restricted eating42:35 Benefits of mini trampolinesMy 2026 longevity routine: https://youtu.be/OceysodInIo100 Health Biomarkers Ranked: https://youtu.be/SgKp5mm0ALI?si=M7YkYo6Lelci7kOQ

Dr. Elie Abirached is a Harvard alumnus, and founder of Restore. He is the creator of the Limitless Human methodology, a science driven framework designed to reduce biological age, enhance resilience, and optimise long term health.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:16 How Elie got into fitness and wellness07:00 Why recovery is not enough11:14 How Elie got a VO2 max of 70 in his 50s16:20 Bon Charge sponsorship17:15 Why VO2 max is such a good biomarker of overall health19:25 Elie's scientific approach to increase VO2 max22:30 Low intensity vs high intensity training27:16 How to know your true maximum heart rate34:25 How often should you test VO2 max36:20 Elie's go-to workouts44:18 Elie's go-to recovery strategies48:44 Elie's nutrition55:10 Elie's supplementation01:00:24 How to start: beginners and advanced individualsDr Elie Abirached's YouTube channel: https://www.youtube.com/@DrElie-biohackingDr Elie Abirached's Instagram: https://www.instagram.com/elie.truth

Dr. Daniel Promislow, DPhil, is a Senior Scientist and Scientific Advisor at the HNRCA. He has worked for over 30 years on the biology of aging and has published over 180 papers. Currently, he's working on the Dog Aging ProjectCheck out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:26 What is the Dog Aging Project02:26 Size and longevity in dogs06:06 Why dog ownership is associated with longevity11:06 Bon Charge sponsorship12:00 What lifestyle makes dogs live longer17:10 Diet for dog longevity19:25 Intermittent fasting for dogs24:20 Calorie restriction for dogs28:35 Exercise for dogs31:55 Rapamycin for dogs45:40 Other longevity compounds for dogs57:35 Supplements for dogsMy 2026 longevity routine: https://youtu.be/OceysodInIo100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:00 Panel members introduction05:20 Recap of our week at AIWO18:30 Blood marker testing20:40 Longevity World Cup competition30:00 DEXA scan36:35 Physiotherapy and posture analysis37:55 Skin anti-aging treatments41:55 Exosomes and stem cells for skin anti-aging49:20 Unique tests we did at AIWO52:45 Social experience at the retreatInka Land YouTube: https://www.youtube.com/@iaminkalandDr Joy Kong YouTube: https://www.youtube.com/@JoyKongMDDave Pascoe YouTube: https://www.youtube.com/c/davepascoesurlAdam Ficsor YouTube: https://www.youtube.com/@nopara73Check out our next retreat: https://www.siimland.co/retreatMy 2026 longevity routine: https://youtu.be/OceysodInIo100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyiStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Timestamps:00:00 Why does longevity matter03:25 Tracking for preventing chronic diseases06:14 Advanced longevity therapies we’re excited about10:30 How long would you like to live14:25 Will longevity technology become available to everyone17:27 Big moonshots in longevity23:32 What does the life of a 70 year old look like in 204026:32 Most important step towards your longevity you should take today28:10 Most overhyped and underrated longevity product30:25 Emotional health33:40 Research on mushroomsPanel discussion at Copenhagen Health Week 2025: https://www.youtube.com/@CPHHW/videosWith Julian Assa and Jürgen MehrtensStart rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:44 My results in 202506:19 Body composition goals16:00 Bon Charge sponsorship16:52 My 2025 fitness results25:05 My 2026 fitness goals30:25 My workout plan for 202635:05 My nutrition plan for 202643:27 My supplement protocol for 202646:37 My sleep routine and goals48:47 My bloodwork results for 2025 and goals for 202601:01:07 Auxiliary routines01:05:05 ConclusionGet to top 1% health: https://youtu.be/8M9uHhFf26cJoin our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Start rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:15 100 supplements ranked from worst to best57:00 Bon Charge sponsorship57:55 How to eliminate microplastics and heavy metals from your body feat Dr Anil Bajnath01:27:20 Nutrition masterclass with Physionic and Dr Greg Potter02:27:25 Exercise masterclass with Physionic and Dr Greg Potter03:17:15 Best performing video of the year03:29:30 Top underrated video of the year03:36:14 Sleep and circadian clock dysfunction feat Dr Greg Potter04:04:38 Skin anti-aging masterclass with Dr Alexis OrtegaGet to top 1% health: https://youtu.be/8M9uHhFf26c

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:15 Zone 2 cardio01:44 Napping03:03 Walking05:09 Polyphasic sleeping06:47 Mouth breathing07:52 Soleus pushups09:40 Stretching11:10 Mobility12:03 Yoga13:20 HIIT14:20 Sprinting14:48 Plyometrics16:12 Morning sunlight17:05 Evening sunset17:52 Blocking out blue light19:12 Red light therapy20:37 Infrared light21:43 Supplements23:30 Education25:20 Problem solving26:14 Weight lifting26:56 Bilingualism27:10 Sunbathing28:54 Tanning beds30:06 Coffee and teas31:28 Low carb diet33:26 Low fat high carb diet34:04 Vegan diet34:36 Vegetarian diet35:00 Carnivore diet37:07 Paleo diet37:45 Calisthenics39:15 Mediterranean diet40:20 Sugar diet40:58 Hydration41:42 Smoking42:00 Alcohol43:40 Vaping44:00 Mouth tobacco44:35 Hyperbaric oxygen therapy (HBOT)45:40 Sauna47:09 Total plasma exchange47:53 Meditation48:49 Religion50:10 Purpose51:30 Mindfulness52:14 Intermittent fasting53:15 Low calorie diet55:40 If it fits your macros diet57:30 Pet ownership58:57 Marriage01:00:57 Ice bath01:01:57 Having children01:03:29 Social health01:04:23 Having fun and play01:04:40 Mental health01:05:03 Extended fasting01:07:07 Forest bathing01:08:02 Fasting mimicking diet01:09:10 Juice fasting01:09:41 Dry fasting01:11:16 Protein restriction01:12:17 Hot baths01:13:40 Time-restricted eating01:14:10 Circadian mismatch01:14:50 Sleep consistency01:15:23 Chronic stress01:16:00 Junk food01:16:25 Water filtration01:16:50 Air filtration01:17:00 Outdoor pollution01:17:20 Sitting lifestyle01:17:43 Sleep 7-8 hours01:18:09 Regular bloodtests01:18:40 Continuous glucose monitoring01:19:19 Exercise snacks01:19:57 Standing workdesk01:20:53 Nasal breathing01:21:03 Breathing exercises01:21:38 Recreational drugs and weed01:22:26 Peptides01:23:30 HRT & TRT01:27:04 Sleep 4-6 hours01:27:28 Stem cell therapy01:28:17 Team sports01:28:40 Steroid cycle01:29:10 Grounding01:29:32 Mouth taping01:29:51 Artificial sweeteners01:31:30 Hypochondria01:33:50 OverviewMy 2025 supplement list guide: https://www.siimland.co/supplement-list-2025100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyiGet to top 1% health: https://youtu.be/8M9uHhFf26cStart rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 What level of sports performance is unhealthy04:15 How much protein is bad for aging and longevity11:45 Bon Charge sponsorship12:45 Do I want to reach the longevity escape velocity16:40 Absorbing supplements through the skin18:40 Optimal level of testosterone for longevity22:50 Should you cycle supplements on and off27:26 How I managed to follow a healthy lifestyle in my 20s31:07 How much red light therapy can you do per day33:10 Role of stress in longevity39:35 What to do against smog and air pollution43:50 Training fast twitch muscle fibers instead of lifting weights48:30 My all out supplement stack100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Jon Berner, MD PhD is a board certified Psychiatrist from Seattle with 27 years of experience. He's also published several scientific papers.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Why Dr Berner became interested in lithium04:50 Lithium’s benefits in Alzheimer’s and dementia10:50 Lithium’s effects on mTOR and autophagy12:50 Bon Charge sponsorship13:40 Clinical evidence for lithium in dementia18:20 What’s the optimal dose for lithium26:25 Lithium for bipolar and hyperactive brains29:25 Lithium as potential treatment in neurodegeneration31:55 Lithium’s effects on kidneys34:20 Personal experience with taking lithium40:40 Is it safe to take lithium prophalactically over the counter47:55 Rapamycin synergy with lithium51:45 AI and human developmentDr Berner's practice: https://www.woodinvillepsychiatric.com/100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandYip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen, China. They're developing pharmaceuticals for extending human lifespan. We discuss their first senolytic called PCC1. Timestamps:00:00 Intro00:15 Articles about a pill making people live to 15002:50 What is PCC1 and how is it made07:10 How much can targeting senescence extend lifespan12:25 Bon Charge sponsorship13:15 Dose of PCC1 for senolytic and senomorphic effects18:30 PCC1 extending lifespan in mice by 9.4%23:20 Absorption rate of PCC1 and other senolytics27:10 Senolytics for young vs old age31:10 Human study on PCC134:40 What’s the optimal dose for senolytics38:05 Biomarkers of cell senescence40:10 Senolytic benefits on skin and retina46:35 What’s going on in Chinese longevity science52:10 Future direction of PCC1PCC1 studies: https://lonvibio.com/pages/science

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandBrady Holmer is a science writer and researcher with a Master's degree in Human Performance from the University of FloridaTimestamps:00:00 Intro00:40 Why heat acclimation has performance benefits08:10 How to train heat acclimation12:40 Bon Charge sponsorship13:30 Benefits of the sauna for fitness18:25 Saunas and injury recovery22:30 Cold exposure and exercise performance26:45 Cooling down during and before exercise31:40 How often to train heat acclimation and sauna37:05 Sauna and HRV38:10 How long to stay in the sauna41:15 Electrolytes and dehydration acclimation46:25 Differences between men and women in heat acclimation47:00 Does heat acclimation have longevity benefits49:05 Does cold exposure have longevity benefits54:30 Which research should be done more on heat acclimationFirst podcast with Brady about VO2 max: https://youtu.be/xLDaFhN6h8IBrady Holmer Twitter: https://x.com/B_HolmerBrady Holmer website: https://www.bradyholmer.com/Start rewinding your biological clock: https://www.siimland.co/course

Join our upcoming retreat in January 2026: https://www.siimland.co/retreat Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:45)Improving VO2 Max and cardiovascular health (11:28)Blood tests and metabolic health (16:42)Hormone tests and longevity (21:35)Microbiome tests and toxicity (26:55)Microplastics and environmental toxicity (32:14)Food sensitivity testing (39:01)NAD testing and energy metabolism (41:50)Comprehensive health retreat (49:29)Dr. Joy Kong Youtube channel: https://www.siimland.co/retreat

Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metabolism in 2001.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:25 What are mitochondria03:55 Mitochondria in aging and longevity06:00 Oxidative stress, inflammation, and longevity09:30 Antioxidants and benefits of exercise12:40 Bon Charge sponsorship13:30 Who should take antioxidants21:30 Mark’s antioxidant cocktail study24:30 Why is exercise the best thing for your mitochondria30:35 How endurance training shapes the mitochondria35:10 High intensity interval training36:50 Role of mitochondria in muscle loss42:00 Nutrition for mitochondrial health46:50 Supplements for mitochondrial health53:35 Stimulating mitophagy Dr Mark Tarnopolsky research page: https://scholar.google.com/citations?user=4jhi_KkAAAAJ&hl=en

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longevity14:33 Muscle building genetics19:33 FOXO3 and stress resilience24:53 FOXO3 gene editing32:08 Can telomere lengthening be harmful to some individuals38:58 IGF-1 and growth hormone and longevity50:08 Genetically short sleepers54:38 What you should know about your longevity genesFirst podcast with Tyler about genetics and supplements: https://youtu.be/9GLbTEYewUsTyler Panzner channel: https://www.youtube.com/@drtylerpanzner

Timestamps0:00 – Introduction4:12 – Humans adapt, and that changes the rules9:58 – Diet diversity, sensitivities, and n of 116:51 – Assess first: biomarkers that predict disease risk18:27 – Fixing sleep, movement, diet, environment22:47 – Caution on rapamycin, metformin, methylene blue25:54 – FOXO3 stem-cell study and what it means37:15 – Mindset and willpower as real enhancers41:44 – TMG, astaxanthin, melatonin, creatine47:09 – VO2 max priorities and performance trade-offs48:51 – Balancing fitness with joy and purpose53:18 – Biomarkers mediate risk more than labels1:01:00 – 2030–2040: what is realistic1:04:02 – Immortality probabilities and living well nowJulian Issa video podcast: https://youtu.be/vV8yMVGLG6Y?si=XiLxOx0bSSM-xT-v

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Does exercise increase inflammation03:03 Melatonin megadosing research04:23 NOVOS vs Blueprint VS DoNotAge07:44 Hidden things that contribute to my health12:14 Bon Charge sponsorship13:05 How to improve night shift work15:40 Supplements to take before the sauna17:15 Does caffeine age the brain19:34 Can you make up for lost sleep20:40 Thoughts on Urolithin A23:14 Doing too much for longevity27:59 How to stop waking up at 3AM30:57 How much sodium do I consume33:20 Do sleep supplements blunt natural sleep37:07 Inflammation in longevity41:23 Importance of good relationship with food

Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025Timestamps:00:00 Intro00:14 Taurine01:19 Apigenin01:55 Resveratrol03:20 Rapamycin04:55 Metformin06:11 Calcium AKG07:30 Melatonin08:16 SIRT609:05 NAC09:43 NMN, NR, Niacinamide11:10 Niacin13:58 Glycine15:16 Spermidine16:44 Omega-3s17:40 Creatine18:48 Pterostilbene19:19 Magnesium20:16 Vitamin K220:45 Sulforaphane21:34 Curcumin22:08 Methylated B vitamins22:33 Glutathione24:08 Lithium24:55 Lutein & Zeaxanthin25:30 Vitamin C26:29 Ergothioneine27:23 Methylene blue28:46 Multivitamin29:37 Aged garlic extract30:22 Astaxanthin31:06 TMG31:50 Ginger32:15 CoQ1032:53 PQQ33:24 Chondroitin33:45 MSM32:25 Glucosamine34:54 Conclusion100 supplements ranked worst to best: https://youtu.be/W8DZbYyuDmAJoin our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/

Chris Dancy is called 'the most connected man on Earth' because of his pioneering use of technology in everyday life and health optimization.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:23 Why Chris is the most connected man on earth03:38 How Chris used technology to lose weight and get healthy08:43 How technology changes the human experience in the future10:43 Best tools 16:28 The technology Renaissance period20:43 Bon Charge sponsorship21:38 Implants24:18 Hacking time33:28 Meditation and mindfulness36:48 Does time go by faster if you’re stuck in daily routines47:38 How Chris’ perception of time has changed as he got older52:43 Will virtual reality extend perception of lifespan59:03 How to make technology better for your healthChris Dancy website: https://www.chrisdancy.com/

Josh Witteldorf is a PhD in physics who pivoted to researching aging and investigated the evolutionary reasons for aging and human lifespan. He's written the book Cracking the Aging Code.Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:30 How Josh, as a physicist, got into aging research04:35 Why aging is an evolutionary program13:50 Why humans die and age20:45 Bon Charge sponsorship21:35 Why did aging evolve as an adaptation24:40 Species that are biologically immortal30:25 Shocking way group selection selects for aging and death33:55 How predator-prey relations select for aging43:15 Can humans control our own evolution48:15 A long-term human calorie restriction experiment in Biosphere 252:50 Insulin’s effects on aging 55:20 mTOR and aging57:15 Can you deprogram aging and extend lifespan01:10:00 Gene editing01:15:15 Josh’s predictions for the futureJosh Mitteldorf blog: https://scienceblog.com/joshmitteldorf/ Josh's book Cracking the Aging Code: https://amzn.to/4mFmC6mStart rewinding your biological clock: https://www.siimland.co/course

Get my free bloodwork cheat sheet: https://www.siimland.co/bloodwork-cheat-sheetTimestamps:00:00 Intro00:32 Resting heart rate02:27 hsCRP03:32 VLDL03:52 LDL particle count04:31 Homocysteine 05:26 Respiratory rate06:30 VO2 max07:36 Body fat percentage09:18 BMI11:57 HRV14:14 Waist circumference and waist to hip ratio16:00 Visceral fat mass and liver fat18:42 White blood cells20:35 Albumin21:11 Muscle mass22:40 Grip strength24:15 Appendicular lean mass index25:31 Creatinine27:55 eGFR29:20 Cystatin C29:32 Biological age tests31:45 Speed of aging test32:45 Phenoage34:25 Bone density36:00 Lung force36:59 Lp(a)38:15 Oxidized LDL39:00 Testosterone43:40 SHBG45:22 Estradiol (E2)46:42 Resting metabolic rate49:00 Body temperature51:48 Liver enzymes (ALT, AST, GGT, ALP)53:14 ApoB55:10 IGF-157:30 ApoA59:30 Calcium score in the arteries (CAC)01:00:46 Carotid intima media thickness (CIMT)01:03:18 Iodine01:05:09 Thyroid hormones (T3 and T4)01:08:00 Progesterone and pregnenolone01:08:51 Thyroid-stimulating hormone (TSH)01:09:47 BNP (cardiac stress)01:10:22 Hemoglobin01:11:22 Iron and ferritin01:12:56 Uric acid01:13:49 HDL cholesterol01:14:53 HbA1c01:15:39 Fasting insulin01:15:58 Fasting glucose01:17:23 Fructosamine01:18:11 Triglycerides01:19:07 Omega-3 index01:20:26 Omega-6-to-3 ratio01:21:01 Red cell distribution width (RDW)01:21:22 Platelets01:22:22 Mean corpuscular volume (MCV)01:22:39 LDL cholesterol01:23:18 Mean corpuscular hemoglobin (MCH)01:23:33 Blood urea nitrogen (BUN)01:23:57 DHEA-S01:24:52 Vitamin D01:26:07 HOMA-IR01:26:26 Red blood cells01:26:38 Hematocrit01:27:01 Erythrocyte sedimentation rate (ESR)01:27:38 LP-PLA201:28:15 Electrolytes01:29:09 Total cholesterol01:29:23 B vitamins01:30:29 Total iron binding capacity (TIBC) and transferrin saturation01:31:00 Heavy metals01:32:48 Microplastics01:34:54 Cortisol01:36:10 TNF-alpha01:36:50 How much can you lift?01:39:22 Cooper test01:40:25 Microbiome diversity01:42:08 Conclusion100 supplements ranked worst to best: https://youtu.be/W8DZbYyuDmA

Greg Potter, PhD, is a circadian rhythm and time-restricted eating expert who researches sleep, circadian rhythms, and time-restricted eatingCheck out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro01:05 Circadian clock dysfunction and hallmarks of aging10:35 How the circadian clocks affect aging and lifespan17:00 Bon Charge sponsorship17:55 Why clock dysfunction contributes to aging24:50 What causes circadian clock dysfunction30:00 NAD metabolism and clock function31:30 Calorie restriction and meal timing36:00 Night owls vs morning larks39:35 Shift work42:18 Melatonin supplementation46:00 Clock enhancing nutraceuticals49:10 Should you supplement melatonin at old age59:45 Morning cortisol circadian rhythm01:04:50 Sunlight and UV & infrared light exposure01:09:05 How to keep your circadian clock system working well during agingGreg Potter YouTube channel: https://www.youtube.com/@gregpotterphd Greg Potter PhD Instagram: https://www.instagram.com/gregpotterphd/Exercise roundtable with Greg and Nic: https://youtu.be/8eW5gNiSxUULongevity supplement roundtable with Greg and Nic: https://youtu.be/OBPacg_tVuQ

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:22 Dr Robbins background in longevity research01:57 What is cell senescence07:52 Benefits of senescent cells early in life09:07 Does eliminating senescent cells increase lifespan14:50 How to eliminate senescent cells17:35 Most researched senolytics22:15 Can you reverse the age of senescent cells24:00 Immune system and aging26:20 Rapamycin29:20 Practical tips to reduce your senescent cell burden33:50 Are GLP-1 receptor agonists anti-aging drugs36:55 Should people take senolytics41:05 Gene therapies for senescent cells50:45 What things need to be focused on for breakthroughs in longevity researchDr. Robbins is a Professor of Biochemistry, Molecular Biology and Biophysics and Associate Director of the Masonic Institute on the Biology of Aging and Metabolism (MIBAM) and the Medical Discovery Team on the Biology of Aging at the University of Minnesota. Paul Robbins Research lab: https://robbins.umn.edu/Full routine to go from average to top 1% health: https://youtu.be/dHfhTQSBAfg➡ Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Start rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:20 Greg and Siim's background06:35 Our opinion on what’s the best diet12:50 What is most important: how much you eat, what you eat, when you eat18:15 Bon Charge sponsorship19:05 How important is the timing of when you eat42:30 Best diet for top 1% longevity, top 1% athletics and general wellbeing53:00 How to structure your calories, protein, carbs and fats01:07:15 Better and worse forms of protein, carbs and fats01:30:20 Low protein vs high protein for longevity02:09:25 Low carb vs plant-based diet02:10:00 Diet tribalism on social media02:33:00 Final wordsExercise roundtable with Greg and Nic: https://youtu.be/8eW5gNiSxUULongevity supplement roundtable with Greg and Nic: https://youtu.be/OBPacg_tVuQGreg Potter YouTube channel: https://www.youtube.com/@gregpotterphdGreg Potter PhD Instagram: https://www.instagram.com/gregpotterphd/Physionic Instagram: https://www.instagram.com/physionic_phd/Physionic YouTube channel: https://www.youtube.com/@PhysionicStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Get your free personalized health review: https://www.siimland.co/reviewTimestamps:00:00 Intro01:10 Summary of our biomarker differences02:30 Fitness markers09:45 Body composition markers14:45 Inflammation and immune markers19:30 Metabolic health markers24:15 Cardiovascular markers36:30 Kidney markers43:45 Liver markers47:00 Hormone markers53:20 Experimental longevity tests56:45 PhenoAge biological age test01:01:40 RecapMy Evidence-Based Longevity Routine: https://youtu.be/4xkRcfeGDooStart rewinding your biological clock: https://www.siimland.co/course

Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025Timestamps:00:00 Intro00:16 Ca-AKG01:00 NAD Boosters02:54 Senolytics03:53 Glycine and trimethylglycine04:54 Glucosamine sulfate05:25 Taurine05:48 MSM and chondroitin sulfate06:18 Turmeric06:50 Ashwagandha07:52 Citrulline08:02 Thiamine08:40 Chromium09:14 Melatonin09:44 Theanine10:00 Rhodiola rosea10:24 Vitamin C11:01 Methylated B vitamins11:20 Ginger11:37 Sulforaphane11:52 Resveratrol and pterostilbene13:15 Rapamycin14:16 Metformin15:25 Spermidine and wheat germ16:50 Multivitamin17:40 Vitamin E tocotrienols18:10 Methylene blue18:49 Nicotine19:30 Lutein & zeaxanthin & lycopene20:41 Beta-carotene21:40 Molecular hydrogen22:10 Cocoa flavanols22:27 Spirulina22:58 Berberine23:25 Creatine24:14 Vitamin E tocopherol24:27 Aspirin25:35 Vitamin D326:45 Magnesium27:38 Collagen peptides28:10 Glutathione28:47 Vitamin K29:09 Carnosine29:36 Whey protein29:56 Amino acids31:09 Glutamine31:40 Psyllium husk32:08 Caffeine33:33 Aged garlic extract34:01 Ergothioneine34:46 Red yeast rice extract35:39 Tongkat ali36:06 DHEA36:40 Lithium37:52 Omega-338:18 SIRT638:41 NAC39:19 CoQ1040:01 PQQ40:32 Hyaluronic acid41:02 Boron41:20 Inositol41:30 Electrolytes42:35 Zinc43:08 Ginseng43:19 Shilajit43:44 Gingko biloba44:09 EGCG44:42 Tribulus terrestris45:15 Turkesterone45:45 MCT oil47:00 Iron47:40 GHK-Cu48:55 Iodine50:01 Calcium50:31 Beta-alanine51:09 HMB51:41 Saffron52:25 Probiotics and prebiotics53:45 Nattokinase54:32 Digestive enzymes55:11 AstaxanthinTop 15 Evidence-Based Supplements: https://youtu.be/jrozJ6oMEjo

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro01:10 New research in cancer04:35 Circadian rhythms and chemotherapy07:55 Does living close to golf courts increase Parkinson’s and cancer risk11:35 Does glyphosate increase cancer risk13:40 Do you need to worry about cancer if you’re young17:20 Why cancer rates are rising in younger people21:00 Join my Skool community 22:10 Can stress and negative emotions cause cancer27:40 What does it feel to have cancer in the early stages30:35 How much exercise to reduce cancer risk35:15 Should you filter your tap water36:30 Difference between a benign tumor and cancerous tumor40:15 Can the body get rid of cancer on its own42:10 Should you avoid milk and cheese45:25 Processed meat and cured meats47:15 Why can some people live years with cancer49:00 Cancer risk from everyday household items51:35 Can you reverse damage from smoking and alcohol in the context of cancer54:15 Specific biomarkers for cancer risk56:15 Any supplements that have cancer preventive effectsDr Joe Zundell YouTube channel: https://www.youtube.com/@dr.joezundellDr Joe Zundell Instagram: https://www.instagram.com/dr.joezundell/Start rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:35 Why exercise and physical activity matters05:05 What exercises does to your health12:15 Bon Charge Sponsorship13:05 Dangers of sedentary behavior14:00 Why exercise improves health20:25 Why you need to build a reserve23:35 Physionic’s current workout routine27:25 Greg’s current workout routine30:05 Siim’s current workout routine32:55 Cardio vs weights – which one is better47:25 How much exercise is too much55:10 Exercise and respiratory tract infections56:30 Arterial plaque in ultraendurance athletes01:06:25 How much moderate and vigorous exercise isbeneficial01:07:50 How long do athletes live01:14:45 Is too much resistance training harmful to you01:22:40 Protein intake and mortality01:27:15 Strength vs muscle vs power01:44:50 Physionic’s dumbest workout mistakes01:46:05 Greg’s dumbest workout mistakes01:49:00 Siim’s dumbest workout mistakes01:51:15 Youthspan Society Ad01:52:25 Why is VO2 max such a strong predictor of longevity02:06:40 Zone 2 cardio vs HIIT cardio02:16:00 Walking02:22:00 Balance and mobility02:31:40 Only one exercise we could do for the rest of ourlife02:35:45 Final thoughts Greg Potter YouTube channel: https://www.youtube.com/@gregpotterphd Greg Potter PhD Instagram: https://www.instagram.com/gregpotterphd/Physionic Instagram: https://www.instagram.com/physionic_phd/ Physionic YouTube channel: https://www.youtube.com/@Physionic Join Youthspan Society community: https://www.skool.com/youthspan-society-9710/about

Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:35 Is Detox a Scam05:20 How the body detoxifies itself16:18 Bon Charge sponsorship17:10 How to support daily detoxification pathways30:45 Mineral waters and mineral baths37:10 Do binders like clay and charcoal work41:10 Are there supplements that support detox45:55 Therapeutic detox therapies47:45 Fix your gut before detoxing55:45 Organic food, grass-fed, and water filters01:03:25 Protocol for mold illness01:18:18 Protocol for heavy metal toxicity01:23:25 Protocol for microplastics01:29:45 Anil’s new book Dr Anil Bajnath Instagram: https://www.instagram.com/dranilbajnath/Order my new book: https://www.amazon.com/dp/B0CW1B2XM1    

Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:18 Kristi’s new study on zone 2 cardio07:33 Does zone 2 provide unique mitochondrial benefits12:58 VO2 max15:18 Bon Charge sponsorship16:08 Why athletes do so much zone 2 training20:43 How much volume of exercise you need for mitochondrial adaptations25:43 Is zone 2 better than HIIT over a longer time period?32:38 How high heart rate for HIIT33:38 Training for athletes vs general population35:43 Too much high intensity training40:58 Why I do zone 2 training mostly44:18 The limited evidence about the optimal training protocol46:08 Did Kristi change her workout plan based on her research48:18 How long HIIT intervals are optimalKristi Storoschuk Instagram: https://www.instagram.com/krististoroschuk/

Roundtable discussion with Dr. Greg Potter ( @gregpotterphd ) and Dr Nicolas Verhoeve ( @Physionic )Timestamps:00:00 Intro00:28 What supplements and/or pharmaceuticals we would give people05:58 Underrated longevity supplements08:35 Underrated medications13:40 The stupidest things we've done for health24:00 Omega-3 fatty acids (fish oil, algal oil) and longevity26:20 Vitamin D and longevity29:40 Do multivitamins affect longevity?34:45 Factors to consider when selecting longevity supplements50:50 The importance of when you take longevity supplements01:01:30 Supplement interactions with genetics, medications and lifestyle01:03:50 Longevity supplements and drugs that interfere with responses to exercise01:18:38 NAD+ -boosting supplements: effects on NAD+ and biomarkers of health and ageing01:34:00 Is resveratrol or pterostilbene good for longevity?01:39:40 Trigonelline and ergothioneine as alternative ways of raising NAD+01:41:30 Trace lithium as a longevity supplement01:44:20 (Calcium) AKG as a longevity supplement01:49:10 Glycine and glyNAC as longevity supplements02:04:20 Taurine as a longevity supplement02:09:35 Some longevity supplements might benefit vegans and vegetarians more02:13:35 Ergothioneine as a longevity supplement02:22:00 Might ergothioneine be a more effective way to increase NAD+?02:26:25 Astaxanthin as a longevity supplement02:31:05 Fatty15 and urolithin A02:35:50 The promise of nobiletin as a clock-enhancing supplementGreg Potter YouTube channel: https://www.youtube.com/@gregpotterphd Greg Potter PhD Instagram: https://www.instagram.com/gregpotterphd/Physionic Instagram: https://www.instagram.com/physionic_phd/ Physionic YouTube channel: https://www.youtube.com/@Physionic➡ Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:58 How I started writing books04:28 Main keys of fat loss diets09:48 Supplements for fat loss10:33 Effects of diet sodas on fat loss13:48 Metformin effects on longevity17:38 How to optimize sleep23:33 Melatonin supplementation26:30 Calories and energy balance shortcomings30:15 Exercise32:25 Siim’s exercise plan38:45 Top tips for longevity based on research46:30 What’s next for me48:15 Advice for my younger selfCJ's YouTube channel: https://www.youtube.com/@shiftwithcj795 Top 15 supplements to take: https://www.youtube.com/watch?v=jrozJ6oMEjo&ab_channel=SiimLand